Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 116544252 | . | G | A | CCDS5768.1:NM_006136.2:c.241Gac>Aac_NP_006127.1:p.81D>N | Homo sapiens capping actin protein of muscle Z-line alpha subunit 2 (CAPZA2), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5nw4 | 13 | A0PFK5 | 87.06 | 0.0 |
EM |
2017-08-02 | ASP | U:81 | Y:81 | 67.0 | 0.447 | B | -64.8 | 106.6 | 67.0 | 0.447 | 0.0 | ||||||
| 6f1t | 4 | A0PFK5 | 87.06 | 0.0 |
EM |
2018-01-17 | ASP | K:81 | K:81 | 59.0 | 0.393 | -170.3 | 161.6 | 59.0 | 0.393 | 0.0 | |||||||
| 6f1u | 2 | A0PFK5 | 87.06 | 0.0 |
EM |
2018-01-17 | ASP | D:81 | K:81 | 59.0 | 0.393 | -170.3 | 161.6 | 59.0 | 0.393 | 0.0 | |||||||
| 6f38 | 4 | A0PFK5 | 87.06 | 0.0 |
EM |
2018-01-17 | ASP | K:81 | K:81 | 58.0 | NA | -61.7 | 149.1 | 58.0 | NA | NA | |||||||
| 6f3a | 4 | A0PFK5 | 87.06 | 0.0 |
EM |
2018-01-17 | ASP | K:81 | K:81 | 63.0 | NA | B | -72.1 | 148.6 | 63.0 | NA | NA | ||||||
| 6znl | 4 | A0PFK5 | 87.06 | 0.0 |
EM |
2020-07-29 | ASP | K:81 | K:81 | 39.0 | 0.26 | -145.7 | 125.8 | 39.0 | 0.26 | 0.0 | |||||||
| 1izn | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2003-04-08 | ASP | A:81 | A:81 | 66.0 | 0.44 | B | -73.4 | 101.2 | 66.0 | 0.44 | 0.0 | ||||||
| ASP | C:81 | C:81 | 68.0 | 0.453 | B | -77.1 | 103.4 | NA | NA | NA | |||||||||||||
| 2kz7 | 1 | P13127 | 86.01 | 0.0 |
NMR |
2010-07-14 | ASP | A:81 | A:81 | 66.0 | 0.44 | B | -73.5 | 101.2 | 66.0 | 0.44 | 0.0 | ||||||
| 3aa0 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-08-04 | ASP | A:81 | A:81 | 73.0 | 0.487 | E | -69.8 | 118.1 | 73.0 | 0.487 | 0.0 |
HOH |
2.614 |
OD2 |
O |
||
| 3aa1 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-08-04 | ASP | A:81 | A:81 | 80.0 | 0.533 | E | -68.6 | 112.5 | 80.0 | 0.533 | 0.0 |
MES HOH |
7.598 2.673 |
C OD2 |
O1 O |
||
| 3aa6 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-08-04 | ASP | A:81 | A:81 | 76.0 | 0.507 | B | -71.8 | 110.8 | 76.0 | 0.507 | 0.0 |
HOH |
2.577 |
OD2 |
O |
||
| 3aa7 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-08-04 | ASP | A:81 | A:81 | 73.0 | 0.487 | E | -68.9 | 120.7 | 73.0 | 0.487 | 0.0 |
HOH |
2.340 |
OD2 |
O |
||
| 3aaa | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-08-04 | ASP | A:81 | A:81 | 67.0 | 0.447 | E | -61.9 | 109.4 | 67.0 | 0.447 | 0.0 |
HOH |
2.437 |
OD2 |
O |
||
| 3aae | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-11-17 | ASP | A:81 | A:81 | 72.0 | 0.48 | B | -67.1 | 126.0 | 72.0 | 0.48 | 0.0 | ||||||
| ASP | C:81 | C:81 | 71.0 | 0.473 | B | -65.2 | 125.2 | NA | NA | NA | |||||||||||||
| ASP | E:81 | E:81 | 70.0 | 0.467 | B | -68.5 | 124.7 | NA | NA | NA | |||||||||||||
| ASP | G:81 | G:81 | 74.0 | 0.493 | B | -66.9 | 124.2 | NA | NA | NA | |||||||||||||
| ASP | I:81 | I:81 | 69.0 | 0.46 | B | -66.1 | 126.9 | NA | NA | NA | |||||||||||||
| 3lk2 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-04-07 | ASP | A:81 | A:81 | 74.0 | 0.493 | E | -63.6 | 115.8 | 74.0 | 0.493 | 0.0 |
HOH |
2.600 |
OD2 |
O |
||
| 3lk3 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-04-07 | ASP | A:81 | A:81 | 77.0 | 0.513 | E | -70.4 | 106.9 | 77.0 | 0.513 | 0.0 |
HOH |
2.596 |
OD2 |
O |
||
| 3lk4 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2010-04-07 | ASP | A:81 | A:81 | 74.0 | 0.493 | B | -69.1 | 113.5 | 74.0 | 0.493 | 0.0 |
HOH |
2.932 |
OD2 |
O |
||
| ASP | D:81 | D:81 | 73.0 | 0.487 | B | -67.6 | 112.5 | NA | NA | NA | |||||||||||||
| ASP | G:81 | G:81 | 74.0 | 0.493 | B | -68.2 | 111.9 | NA | NA | NA | |||||||||||||
| ASP | J:81 | J:81 | 74.0 | 0.493 | B | -68.1 | 111.8 | NA | NA | NA | |||||||||||||
| ASP | M:81 | M:81 | 73.0 | 0.487 | B | -71.6 | 112.6 | NA | NA | NA | |||||||||||||
| ASP | P:81 | P:81 | 74.0 | 0.493 | B | -71.8 | 113.7 | NA | NA | NA | |||||||||||||
| ASP | S:81 | S:81 | 73.0 | 0.487 | B | -68.9 | 112.4 | NA | NA | NA | |||||||||||||
| ASP | V:81 | V:81 | 74.0 | 0.493 | B | -70.1 | 113.8 | NA | NA | NA | |||||||||||||
| ASP | Y:81 | Y:81 | 72.0 | 0.48 | B | -69.4 | 113.4 | NA | NA | NA | |||||||||||||
| ASP | BA:81 | 1:81 | 74.0 | 0.493 | B | -70.3 | 113.4 | NA | NA | NA | |||||||||||||
| ASP | EA:81 | 4:81 | 73.0 | 0.487 | B | -69.7 | 113.3 | NA | NA | NA | |||||||||||||
| ASP | HA:81 | 7:81 | 74.0 | 0.493 | B | -69.3 | 114.0 | NA | NA | NA | |||||||||||||
| 7ds2 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 72.0 | 0.48 | E | -69.5 | 111.1 | 72.0 | 0.48 | 0.0 |
HOH |
2.597 |
OD1 |
O |
||
| 7ds3 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 74.0 | 0.493 | E | -66.6 | 107.9 | 74.0 | 0.493 | 0.0 |
HOH |
2.447 |
OD1 |
O |
||
| 7ds4 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 78.0 | 0.52 | E | -76.5 | 109.0 | 78.0 | 0.52 | 0.0 |
HOH |
2.366 |
OD2 |
O |
||
| 7ds6 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 75.0 | 0.5 | E | -74.4 | 105.1 | 75.0 | 0.5 | 0.0 |
HOH |
2.655 |
OD1 |
O |
||
| 7ds8 | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 78.0 | 0.52 | E | -73.5 | 108.5 | 78.0 | 0.52 | 0.0 |
HOH |
2.537 |
OD2 |
O |
||
| 7dsa | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 66.0 | 0.44 | B | -69.6 | 119.4 | 66.0 | 0.44 | 0.0 |
HOH |
3.462 |
OD2 |
O |
||
| 7dsb | 1 | P13127 | 86.01 | 0.0 |
X-RAY |
2021-03-03 | ASP | A:81 | A:81 | 66.0 | 0.44 | E | -70.7 | 111.1 | 66.0 | 0.44 | 0.0 | ||||||
| 7ccc | 3 | Q5RKN9 | 86.01 | 0.0 |
X-RAY |
2021-02-03 | ASP | C:81 | C:81 | 70.0 | 0.467 | B | -70.1 | 134.4 | 70.0 | 0.467 | 0.0 |
HOH |
8.140 |
N |
O |
||
| 7pdz | 2 | P47753 | 86.01 | 0.0 |
EM |
2021-09-01 | ASP | B:81 | F:81 | 58.0 | 0.387 | B | -66.8 | 121.1 | 58.0 | 0.387 | 0.0 | ||||||
| 5adx | 4 | A0PFK5 | 87.27 | 7e-179 |
EM |
2015-12-30 | ASP | K:75 | K:81 | 66.0 | 0.44 | B | -64.8 | 106.6 | 66.0 | 0.44 | 0.0 | ||||||
| 5afu | 8 | A0PFK5 | 87.27 | 7e-179 |
EM |
2015-03-11 | ASP | Q:75 | K:81 | 66.0 | 0.44 | B | -64.8 | 106.6 | 66.0 | 0.44 | 0.0 | ||||||
| 2kxp | 1 | P13127 | 86.18 | 1e-177 |
NMR |
2010-06-09 | ASP | A:75 | A:81 | 72.0 | 0.48 | B | -85.5 | 100.0 | 72.0 | 0.48 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p47755-f1 | 1 | P47755 | 100.0 | 0.0 | ASP | A:81 | A:81 | 73.0 | 0.487 | B | -68.6 | 118.2 | |
| af-p52907-f1 | 1 | P52907 | 86.71 | 0.0 | ASP | A:81 | A:81 | 70.0 | 0.467 | B | -67.8 | 118.4 | |