Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 116550321 . A C CCDS5768.1:NM_006136.2:c.541Atc>Ctc_NP_006127.1:p.181I>L Homo sapiens capping actin protein of muscle Z-line alpha subunit 2 (CAPZA2), mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5nw4 13 A0PFK5 87.06 0.0 EM
 2017-08-02 ILE U:181 Y:181 28.0 0.16 -89.9 117.6 28.0 0.16 0.0
6f1t 4 A0PFK5 87.06 0.0 EM
 2018-01-17 ILE K:181 K:181 6.0 0.034 E -85.9 79.7 6.0 0.034 0.0
6f1u 2 A0PFK5 87.06 0.0 EM
 2018-01-17 ILE D:181 K:181 6.0 0.034 E -85.9 79.7 6.0 0.034 0.0
6f38 4 A0PFK5 87.06 0.0 EM
 2018-01-17 ILE K:181 K:181 47.0 NA E -71.7 100.1 47.0 NA NA
6f3a 4 A0PFK5 87.06 0.0 EM
 2018-01-17 ILE K:181 K:181 54.0 NA E -74.9 100.6 54.0 NA NA
6znl 4 A0PFK5 87.06 0.0 EM
 2020-07-29 ILE K:181 K:181 0.0 0.0 -77.0 108.3 0.0 0.0 0.0
1izn 1 P13127 86.01 0.0 X-RAY
 2003-04-08 ILE A:181 A:181 14.0 0.08 -86.1 129.0 14.0 0.08 0.0 HOH
 7.361
 O
 O
ILE C:181 C:181 18.0 0.103 E -87.4 105.8 NA NA NA
2kz7 1 P13127 86.01 0.0 NMR
 2010-07-14 ILE A:181 A:181 16.0 0.091 -86.1 129.0 16.0 0.091 0.0
3aa0 1 P13127 86.01 0.0 X-RAY
 2010-08-04 ILE A:181 A:181 13.0 0.074 E -96.5 111.0 13.0 0.074 0.0 HOH
 2.735
 O
 O
3aa1 1 P13127 86.01 0.0 X-RAY
 2010-08-04 ILE A:181 A:181 15.0 0.086 -82.5 72.7 15.0 0.086 0.0 HOH
 3.160
 O
 O
3aa6 1 P13127 86.01 0.0 X-RAY
 2010-08-04 ILE A:181 A:181 22.0 0.126 E -83.3 114.7 22.0 0.126 0.0 HOH
 2.800
 O
 O
3aa7 1 P13127 86.01 0.0 X-RAY
 2010-08-04 ILE A:181 A:181 17.0 0.097 E -92.5 105.5 17.0 0.097 0.0 HOH
 2.465
 O
 O
3aaa 1 P13127 86.01 0.0 X-RAY
 2010-08-04 ILE A:181 A:181 10.0 0.057 E -90.6 118.0 10.0 0.057 0.0 HOH
 2.863
 O
 O
3aae 1 P13127 86.01 0.0 X-RAY
 2010-11-17 ILE A:181 A:181 11.0 0.063 E -110.3 106.3 11.0 0.063 0.0
ILE C:181 C:181 12.0 0.069 E -110.2 106.6 NA NA NA
ILE E:181 E:181 10.0 0.057 E -109.7 108.0 NA NA NA
ILE G:181 G:181 10.0 0.057 E -108.5 109.0 NA NA NA
ILE I:181 I:181 11.0 0.063 E -107.8 106.7 NA NA NA
3lk2 1 P13127 86.01 0.0 X-RAY
 2010-04-07 ILE A:181 A:181 25.0 0.143 -76.0 108.3 25.0 0.143 0.0 HOH
 5.186
 N
 O
3lk3 1 P13127 86.01 0.0 X-RAY
 2010-04-07 ILE A:181 A:181 5.0 0.029 E -101.6 116.6 5.0 0.029 0.0 HOH
 9.914
 CG1
 O
3lk4 1 P13127 86.01 0.0 X-RAY
 2010-04-07 ILE A:181 A:181 26.0 0.149 E -78.7 121.0 26.0 0.149 0.0 HOH
 6.864
 N
 O
ILE D:181 D:181 25.0 0.143 E -77.6 120.8 NA NA NA
ILE G:181 G:181 26.0 0.149 E -78.8 119.6 NA NA NA
ILE J:181 J:181 27.0 0.154 E -78.6 121.5 NA NA NA
ILE M:181 M:181 27.0 0.154 E -80.4 119.7 NA NA NA
ILE P:181 P:181 27.0 0.154 E -79.1 121.0 NA NA NA
ILE S:181 S:181 25.0 0.143 E -78.7 121.3 NA NA NA
ILE V:181 V:181 25.0 0.143 E -80.5 120.6 NA NA NA
ILE Y:181 Y:181 26.0 0.149 E -79.1 121.2 NA NA NA
ILE BA:181 1:181 26.0 0.149 E -79.2 120.8 NA NA NA
ILE EA:181 4:181 27.0 0.154 E -78.4 121.8 NA NA NA
ILE HA:181 7:181 27.0 0.154 E -80.0 120.0 NA NA NA
7ds2 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 16.0 0.091 E -96.2 109.9 16.0 0.091 0.0 HOH
 2.427
 O
 O
7ds3 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 21.0 0.12 E -89.9 104.2 21.0 0.12 0.0 HOH
 2.804
 O
 O
7ds4 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 18.0 0.103 E -94.0 105.0 18.0 0.103 0.0 HOH
 5.974
 N
 O
7ds6 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 18.0 0.103 -82.5 78.1 18.0 0.103 0.0 HOH
 5.895
 N
 O
7ds8 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 27.0 0.154 E -85.4 118.1 27.0 0.154 0.0 HOH
 5.539
 O
 O
7dsa 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 13.0 0.074 E -80.4 113.6 13.0 0.074 0.0 HOH
 6.127
 N
 O
7dsb 1 P13127 86.01 0.0 X-RAY
 2021-03-03 ILE A:181 A:181 10.0 0.057 E -77.3 111.5 10.0 0.057 0.0 HOH
 3.042
 O
 O
7ccc 3 Q5RKN9 86.01 0.0 X-RAY
 2021-02-03 ILE C:181 C:181 17.0 0.097 -77.1 101.2 17.0 0.097 0.0
7pdz 2 P47753 86.01 0.0 EM
 2021-09-01 ILE B:181 F:181 30.0 0.171 E -61.9 125.7 30.0 0.171 0.0
5adx 4 A0PFK5 87.27 7e-179 EM
 2015-12-30 ILE K:175 K:181 29.0 0.166 -89.9 117.6 29.0 0.166 0.0
5afu 8 A0PFK5 87.27 7e-179 EM
 2015-03-11 ILE Q:175 K:181 29.0 0.166 -89.9 117.6 29.0 0.166 0.0
2kxp 1 P13127 86.18 1e-177 NMR
 2010-06-09 ILE A:175 A:181 23.0 0.131 -164.3 151.4 23.0 0.131 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p47755-f1 1 P47755 100.0 0.0 ILE A:181 A:181 19.0 0.109 -78.7 82.1
af-p52907-f1 1 P52907 86.71 0.0 ILE A:181 A:181 12.0 0.069 E -90.5 110.0