Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155598990 . C A CCDS5942.1:NM_000193.2:c.562Gag>Tag_NP_000184.1:p.188E>* Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
2021-12-08 GLU A:188 G:188 101.0 0.532 -82.1 179.3 91.0 0.479 0.053 B:Q96F81:0.053
6dmy 2 Q15465 100.0 7e-128 EM
2018-07-11 GLU B:168 B:188 49.0 0.258 -5.2 -108.3 49.0 0.258 0.0 SER
4.210
O
N
6n7g 2 Q15465 100.0 7e-128 EM
2019-05-29 GLU C:165 C:188 153.0 0.805 S -56.8 61.3 153.0 0.805 0.0
GLU F:165 F:188 154.0 0.811 S -56.8 61.3 154.0 0.811 0.0
6n7h 2 Q15465 100.0 7e-128 EM
2019-05-29 GLU C:165 C:188 150.0 0.789 S -56.8 61.3 150.0 0.789 0.0
6n7k 2 Q15465 100.0 7e-128 EM
2019-05-29 GLU C:165 C:188 153.0 0.805 S -56.8 61.3 153.0 0.805 0.0
GLU F:165 F:188 154.0 0.811 S -56.8 61.3 154.0 0.811 0.0
6rvd 2 Q15465 100.0 7e-128 EM
2019-10-02 GLU C:165 C:188 142.0 0.747 S -68.2 145.8 142.0 0.747 0.0
6e1h 2 Q15465 100.0 7e-128 EM
2018-08-29 GLU B:166 NA:NA DO NA DO DO DO NA NA NA
6oev 2 Q15465 100.0 7e-128 EM
2019-04-17 GLU B:166 C:188 184.0 0.968 49.5 360.0 184.0 0.968 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
2010-03-16 GLU A:166 A:188 164.0 0.863 91.9 360.0 164.0 0.863 0.0 SO4
HOH
8.097
3.200
O
N
O1
O
GLU B:166 B:188 97.0 0.511 T -54.0 -38.8 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
2019-10-09 GLU B:276 B:188 221.0 1.0 57.6 360.0 221.0 1.0 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
2009-06-23 GLU C:160 H:188 93.0 0.489 S -70.1 -29.0 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
2010-05-26 GLU A:160 A:188 88.0 0.463 G -51.3 -40.1 88.0 0.463 0.0 SO4
HOH
9.438
2.763
OE1
OE2
O1
O
6pjv 1 Q15465 100.0 2e-123 X-RAY
2019-11-13 GLU A:160 A:188 105.0 0.553 T -60.5 -36.1 105.0 0.553 0.0 HOH
2.165
H
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
2008-09-23 GLU A:168 NA:NA DO NA DO DO DO NA NA NA
GLU B:168 B:189 165.0 NA -67.9 360.0 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
2021-10-27 GLU B:164 H:189 136.0 0.716 -68.8 360.0 136.0 0.716 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
1996-01-29 GLU A:156 A:189 108.0 0.568 H -60.5 -34.6 108.0 0.568 0.0 HOH
1.897
OE2
H1
3k7g 1 Q14623 88.07 1e-112 X-RAY
2011-01-26 GLU A:178 B:193 146.0 0.768 S -86.8 15.4 146.0 0.768 0.0 HOH
2.730
OE2
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
2013-10-02 GLU A:152 A:189 144.0 0.758 -69.8 153.1 144.0 0.758 0.0 HOH
2.792
OE1
O
4c4n 1 Q62226 99.36 1e-112 X-RAY
2013-10-02 GLU A:152 A:189 94.0 0.495 -67.6 129.1 94.0 0.495 0.0 HOH
2.656
OE2
O
GLU B:152 B:189 107.0 0.563 T -59.7 -25.8 107.0 0.563 0.0 HOH
4.861
OE1
O
3n1r 1 Q62226 99.36 2e-112 X-RAY
2010-06-02 GLU A:154 A:189 176.0 0.926 -118.7 360.0 176.0 0.926 0.0 HOH
4.115
N
O
3k7j 1 Q14623 87.5 4e-112 X-RAY
2011-01-26 GLU A:178 NA:NA DO NA DO DO DO NA NA NA
3k7i 1 Q14623 87.5 5e-112 X-RAY
2011-01-26 GLU A:178 B:193 119.0 0.626 S -89.8 15.5 119.0 0.626 0.0 HOH
2.681
OE2
O
3k7h 1 Q14623 87.5 5e-112 X-RAY
2011-01-26 GLU A:178 B:193 125.0 0.658 S -93.6 19.9 125.0 0.658 0.0 HOH
2.690
O
O
2wg4 1 Q62226 99.35 6e-112 X-RAY
2009-06-30 GLU A:150 A:189 130.0 NA -86.4 360.0 130.0 NA NA
2wfx 1 Q62226 99.34 5e-110 X-RAY
2009-06-30 GLU A:150 A:189 95.0 NA S -60.4 -6.5 95.0 NA NA
3n1f 1 Q14623 88.17 7e-107 X-RAY
2010-06-02 GLU A:169 A:193 160.0 NA -63.5 360.0 160.0 NA NA HOH
2.303
H
O
GLU B:169 B:193 172.0 NA -65.8 360.0 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
2010-06-02 GLU A:169 B:193 157.0 NA -54.1 360.0 157.0 NA NA HOH
2.293
H
O
3n1o 1 Q14623 88.17 7e-107 X-RAY
2010-06-02 GLU A:169 A:193 172.0 0.905 -108.1 360.0 172.0 0.905 0.0 HOH
3.525
OE2
O
GLU B:169 NA:NA DO NA DO DO DO NA NA NA
GLU C:169 C:193 162.0 0.853 -65.0 360.0 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
2010-06-02 GLU A:169 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 GLU A:188 A:188 54.0 0.284 T -62.2 -32.5