Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155599058 . G A CCDS5942.1:NM_000193.2:c.494gCg>gTg_NP_000184.1:p.165A>V Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ALA A:165 G:165 0.0 0.0 H -56.9 -35.4 0.0 0.0 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ALA B:145 B:165 0.0 0.0 H -74.1 -30.5 0.0 0.0 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:142 C:165 0.0 0.0 H -70.5 -28.8 0.0 0.0 0.0
ALA F:142 F:165 0.0 0.0 H -70.4 -28.8 0.0 0.0 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:142 C:165 0.0 0.0 H -70.4 -28.8 0.0 0.0 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:142 C:165 0.0 0.0 H -70.5 -28.8 0.0 0.0 0.0
ALA F:142 F:165 0.0 0.0 H -70.4 -28.8 0.0 0.0 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ALA C:142 C:165 0.0 0.0 H -67.6 -35.6 0.0 0.0 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ALA B:143 C:165 0.0 0.0 H -65.6 -32.3 0.0 0.0 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ALA B:143 C:165 0.0 0.0 H -63.9 -39.4 0.0 0.0 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ALA A:143 A:165 0.0 0.0 H -62.5 -45.2 0.0 0.0 0.0 SO4
SO4
HOH
 8.903
9.789
6.535
 C
O
N
 O2
O3
O
ALA B:143 B:165 0.0 0.0 H -67.0 -35.9 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ALA B:253 B:165 0.0 0.0 H -62.4 -27.7 0.0 0.0 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ALA C:137 H:165 0.0 0.0 H -74.1 -31.9 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ALA A:137 A:165 0.0 0.0 H -67.7 -39.4 0.0 0.0 0.0 SO4
HOH
 9.376
4.746
 O
O
 O2
O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ALA A:137 A:165 0.0 0.0 H -67.6 -38.7 0.0 0.0 0.0 HOH
 4.814
 O
 O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ALA A:145 A:166 0.0 0.0 H -64.4 -39.2 0.0 0.0 0.0 HOH
 4.753
 O
 O
ALA B:145 B:166 0.0 0.0 H -65.0 -39.2 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ALA B:141 H:166 0.0 0.0 H -60.6 -47.8 0.0 0.0 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ALA A:133 A:166 0.0 0.0 H -60.0 -39.0 0.0 0.0 0.0 HOH
 4.042
 N
 H2
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ALA A:155 B:170 0.0 0.0 H -62.9 -37.5 0.0 0.0 0.0 SO4
HOH
 9.124
4.700
 C
O
 O2
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ALA A:129 A:166 0.0 0.0 H -66.3 -39.2 0.0 0.0 0.0 HOH
 4.748
 O
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ALA A:129 A:166 0.0 0.0 H -62.6 -39.9 0.0 0.0 0.0 HOH
 4.695
 N
 O
ALA B:129 B:166 0.0 0.0 H -61.0 -40.3 0.0 0.0 0.0 HOH
 4.664
 O
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ALA A:131 A:166 0.0 0.0 H -64.3 -35.3 0.0 0.0 0.0 HOH
 4.805
 O
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ALA A:155 B:170 0.0 0.0 H -63.8 -42.1 0.0 0.0 0.0 SO4
HOH
 9.584
4.783
 C
N
 O4
O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ALA A:155 B:170 0.0 0.0 H -63.3 -37.4 0.0 0.0 0.0 SO4
HOH
 9.122
4.751
 C
O
 O2
O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ALA A:155 B:170 0.0 0.0 H -66.0 -35.7 0.0 0.0 0.0 HOH
 4.757
 O
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ALA A:127 A:166 0.0 0.0 H -69.6 -33.7 0.0 0.0 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ALA A:127 A:166 0.0 0.0 H -71.6 -44.1 0.0 0.0 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:146 A:170 0.0 0.0 H -69.2 -36.6 0.0 0.0 0.0 HOH
 4.822
 O
 O
ALA B:146 B:170 0.0 0.0 H -65.3 -38.0 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:146 B:170 0.0 0.0 H -68.0 -36.7 0.0 0.0 0.0 HOH
 4.777
 O
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:146 A:170 0.0 0.0 H -59.5 -40.7 0.0 0.0 0.0 HOH
 4.452
 N
 O
ALA B:146 B:170 0.0 0.0 H -60.0 -40.2 NA NA NA
ALA C:146 C:170 0.0 0.0 H -67.9 -37.9 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:146 B:170 0.0 0.0 H -55.6 -43.0 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ALA A:165 A:165 0.0 0.0 H -63.9 -39.9