Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155599103 . G A CCDS5942.1:NM_000193.2:c.449aCg>aTg_NP_000184.1:p.150T>M Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 THR A:150 G:150 1.0 0.007 -81.3 -175.0 1.0 0.007 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 THR B:130 B:150 0.0 0.0 -90.8 -179.4 0.0 0.0 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 THR C:127 C:150 1.0 0.007 -82.9 -70.3 1.0 0.007 0.0
THR F:127 F:150 0.0 0.0 -82.9 -70.3 0.0 0.0 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 THR C:127 C:150 0.0 0.0 -82.9 -70.3 0.0 0.0 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 THR C:127 C:150 1.0 0.007 -82.9 -70.3 1.0 0.007 0.0
THR F:127 F:150 0.0 0.0 -82.9 -70.3 0.0 0.0 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 THR C:127 C:150 0.0 0.0 E -91.2 172.3 0.0 0.0 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 THR B:128 C:150 0.0 0.0 E -82.7 164.1 0.0 0.0 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 THR B:128 C:150 2.0 0.014 E -77.5 156.3 2.0 0.014 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 THR A:128 A:150 0.0 0.0 E -85.2 157.5 0.0 0.0 0.0 SO4
HOH
 9.063
4.993
 O
O
 O1
O
THR B:128 B:150 0.0 0.0 E -83.7 159.5 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 THR B:238 B:150 4.0 0.029 E -87.9 173.9 4.0 0.029 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 THR C:122 H:150 0.0 0.0 E -91.0 156.0 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 THR A:122 A:150 0.0 0.0 E -87.7 162.4 0.0 0.0 0.0 HOH
 5.270
 O
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 THR A:122 A:150 0.0 0.0 E -87.8 160.8 0.0 0.0 0.0 GOL
CL
HOH
 6.536
7.874
5.284
 HG21
O
O
 H2
CL
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 THR A:130 A:151 0.0 0.0 E -82.7 156.9 0.0 0.0 0.0 HOH
 6.097
 C
 O
THR B:130 B:151 0.0 0.0 E -87.7 158.5 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 THR B:126 H:151 0.0 0.0 E -70.1 158.9 0.0 0.0 0.0 SO4
 6.716
 O
 O3
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 THR A:118 A:151 0.0 0.0 E -92.4 157.6 0.0 0.0 0.0 SO4
HOH
 6.364
4.592
 O
O
 O1
H2
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 THR A:140 B:155 0.0 0.0 E -91.4 158.8 0.0 0.0 0.0 HOH
 5.327
 O
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 THR A:114 A:151 0.0 0.0 E -94.8 160.5 0.0 0.0 0.0 ASG
ACT
HOH
 8.248
6.358
5.182
 O
O
O
 OSB
O
O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 THR A:114 A:151 0.0 0.0 E -86.8 156.8 0.0 0.0 0.0 IDS
SGN
HOH
 8.593
7.091
8.289
 O
O
OG1
 O3
O2S
O
THR B:114 B:151 0.0 0.0 E -88.0 154.7 0.0 0.0 0.0 SGN
IDS
SGN
HOH
 8.605
8.375
7.337
7.882
 O
O
O
O
 O1S
O6A
O4S
O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 THR A:116 A:151 0.0 0.0 E -85.4 160.1 0.0 0.0 0.0 HOH
 6.522
 O
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 THR A:140 B:155 0.0 0.0 E -83.9 157.2 0.0 0.0 0.0 SO4
HOH
 8.180
5.609
 O
O
 O1
O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 THR A:140 B:155 0.0 0.0 E -88.2 158.9 0.0 0.0 0.0 HOH
 5.296
 O
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 THR A:140 B:155 0.0 0.0 E -90.4 158.9 0.0 0.0 0.0 SO4
HOH
 6.177
5.420
 O
O
 O1
O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 THR A:112 A:151 0.0 0.0 E -82.6 163.7 0.0 0.0 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 THR A:112 A:151 0.0 0.0 E -81.7 172.8 0.0 0.0 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 THR A:131 A:155 0.0 0.0 E -85.6 161.8 0.0 0.0 0.0 HOH
 5.965
 C
 O
THR B:131 B:155 0.0 0.0 E -90.0 161.0 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 THR A:131 B:155 0.0 0.0 E -84.2 161.0 0.0 0.0 0.0 HOH
 5.974
 C
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 THR A:131 A:155 0.0 0.0 E -83.6 161.0 0.0 0.0 0.0 HOH
 6.064
 O
 O
THR B:131 B:155 0.0 0.0 E -86.6 153.3 NA NA NA
THR C:131 C:155 0.0 0.0 E -84.7 156.7 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 THR A:131 B:155 0.0 0.0 E -103.8 136.6 0.0 0.0 0.0 HOH
 9.901
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 THR A:150 A:150 0.0 0.0 E -85.3 154.5