Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155599124 . C A CCDS5942.1:NM_000193.2:c.428gGc>gTc_NP_000184.1:p.143G>V Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 GLY A:143 G:143 0.0 0.0 T 99.0 -3.1 0.0 0.0 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 GLY B:123 B:143 1.0 0.013 T 73.4 18.8 1.0 0.013 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLY C:120 C:143 2.0 0.027 T 67.8 20.5 2.0 0.027 0.0
GLY F:120 F:143 1.0 0.013 T 67.8 20.6 1.0 0.013 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLY C:120 C:143 3.0 0.04 T 67.8 20.5 3.0 0.04 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLY C:120 C:143 2.0 0.027 T 67.8 20.5 2.0 0.027 0.0
GLY F:120 F:143 1.0 0.013 T 67.8 20.6 1.0 0.013 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 GLY C:120 C:143 1.0 0.013 T 65.6 30.1 1.0 0.013 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 GLY B:121 C:143 0.0 0.0 T 72.1 19.5 0.0 0.0 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 GLY B:121 C:143 6.0 0.08 T 98.2 7.7 6.0 0.08 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 GLY A:121 A:143 1.0 0.013 T 69.5 24.1 1.0 0.013 0.0 HOH
 5.066
 CA
 O
GLY B:121 B:143 1.0 0.013 T 71.1 26.5 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 GLY B:231 B:143 0.0 0.0 T 80.8 14.7 0.0 0.0 0.0 ZN
 9.959
 H
 ZN
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 GLY C:115 H:143 1.0 0.013 T 73.4 33.0 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 GLY A:115 A:143 0.0 0.0 T 69.5 24.3 0.0 0.0 0.0 SO4
HOH
 9.752
5.133
 N
N
 O4
O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 GLY A:115 A:143 2.0 0.027 T 71.6 18.0 2.0 0.027 0.0 DMS
HOH
 9.987
2.295
 HA2
H
 H13
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 GLY A:123 A:144 0.0 0.0 T 71.9 22.3 0.0 0.0 0.0 HOH
 2.902
 CA
 O
GLY B:123 B:144 0.0 0.0 T 71.1 25.2 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 GLY B:119 H:144 0.0 0.0 T 69.1 16.4 0.0 0.0 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 GLY A:111 A:144 1.0 0.013 T 62.3 28.7 1.0 0.013 0.0 HOH
 2.969
 CA
 O
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 GLY A:133 B:148 1.0 0.013 T 69.0 29.4 1.0 0.013 0.0 HOH
 3.078
 C
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 GLY A:107 A:144 0.0 0.0 T 68.6 28.3 0.0 0.0 0.0 HOH
 5.101
 N
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 GLY A:107 A:144 0.0 0.0 T 72.3 15.8 0.0 0.0 0.0 HOH
 5.673
 O
 O
GLY B:107 B:144 0.0 0.0 T 71.6 17.0 0.0 0.0 0.0 HOH
 9.305
 CA
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 GLY A:109 A:144 2.0 0.027 T 75.2 27.3 2.0 0.027 0.0 HOH
 2.941
 CA
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 GLY A:133 B:148 1.0 0.013 T 67.2 34.6 1.0 0.013 0.0 HOH
 5.663
 O
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 GLY A:133 B:148 2.0 0.027 T 70.0 27.7 2.0 0.027 0.0 HOH
 3.078
 CA
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 GLY A:133 B:148 1.0 0.013 T 67.6 29.6 1.0 0.013 0.0 HOH
 3.117
 CA
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 GLY A:105 A:144 1.0 0.013 T 59.6 22.7 1.0 0.013 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 GLY A:105 A:144 1.0 0.013 T 74.7 21.7 1.0 0.013 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLY A:124 A:148 0.0 0.0 T 67.9 22.5 0.0 0.0 0.0 ZN
CA
HOH
 9.853
9.865
4.960
 HA2
HA2
N
 ZN
CA
O
GLY B:124 B:148 0.0 0.0 T 65.1 28.6 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLY A:124 B:148 0.0 0.0 T 71.1 19.4 0.0 0.0 0.0 ZN
CA
HOH
 9.815
9.989
2.239
 H
HA2
HA2
 ZN
CA
O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLY A:124 A:148 1.0 0.013 T 65.1 27.9 1.0 0.013 0.0 HOH
 2.943
 CA
 O
GLY B:124 B:148 2.0 0.027 T 61.4 27.3 NA NA NA
GLY C:124 C:148 0.0 0.0 T 70.5 33.0 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLY A:124 B:148 1.0 0.013 T 55.8 30.4 1.0 0.013 0.0 HOH
 8.626
 CA
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 GLY A:143 A:143 0.0 0.0 T 63.3 30.0