Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155599203 . A C CCDS5942.1:NM_000193.2:c.349Tgg>Ggg_NP_000184.1:p.117W>G Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 TRP A:117 G:117 43.0 0.169 S -127.8 113.7 43.0 0.169 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 TRP B:97 B:117 50.0 0.196 S -112.2 138.9 50.0 0.196 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 TRP C:94 C:117 47.0 0.184 S -122.6 129.0 47.0 0.184 0.0
TRP F:94 F:117 46.0 0.18 S -122.7 129.0 46.0 0.18 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 TRP C:94 C:117 46.0 0.18 S -122.6 129.0 46.0 0.18 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 TRP C:94 C:117 47.0 0.184 S -122.6 129.0 47.0 0.184 0.0
TRP F:94 F:117 46.0 0.18 S -122.7 129.0 46.0 0.18 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 TRP C:94 C:117 41.0 0.161 S -106.3 120.2 41.0 0.161 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 TRP B:95 C:117 40.0 0.157 S -120.9 112.0 40.0 0.157 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 TRP B:95 C:117 51.0 0.2 S -120.5 109.7 51.0 0.2 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 TRP A:95 A:117 44.0 0.173 S -132.7 100.0 44.0 0.173 0.0 HOH
 3.284
 NE1
 O
TRP B:95 B:117 41.0 0.161 S -130.7 107.1 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 TRP B:205 B:117 92.0 0.361 S 52.6 72.6 92.0 0.361 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 TRP C:89 H:117 40.0 0.157 S -125.4 108.4 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 TRP A:89 A:117 46.0 0.18 S -128.9 91.3 46.0 0.18 0.0 HOH
 3.702
 CD1
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 TRP A:89 A:117 46.0 0.18 S -134.0 90.4 46.0 0.18 0.0 GOL
HOH
 1.755
2.855
 HZ2
HD1
 H2
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 TRP A:97 A:118 46.0 0.18 S -136.4 95.6 46.0 0.18 0.0 HOH
 3.457
 CD1
 O
TRP B:97 B:118 44.0 0.173 S -134.4 88.4 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 TRP B:93 H:118 46.0 0.18 S -132.3 102.3 46.0 0.18 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 TRP A:85 A:118 43.0 0.169 S -133.3 85.3 43.0 0.169 0.0 HOH
 2.675
 CZ2
 H2
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 TRP A:107 B:122 38.0 0.149 S -131.6 85.0 38.0 0.149 0.0 HOH
 3.188
 NE1
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 TRP A:81 A:118 43.0 0.169 S -131.1 92.3 43.0 0.169 0.0 HOH
 3.603
 NE1
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 TRP A:81 A:118 44.0 0.173 S -126.5 93.2 44.0 0.173 0.0 HOH
 4.128
 O
 O
TRP B:81 B:118 46.0 0.18 S -126.9 94.0 46.0 0.18 0.0 HOH
 4.861
 CD1
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 TRP A:83 A:118 44.0 0.173 S -133.6 80.9 44.0 0.173 0.0 HOH
 3.677
 C
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 TRP A:107 B:122 38.0 0.149 S -129.7 85.1 38.0 0.149 0.0 HOH
 2.667
 NE1
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 TRP A:107 B:122 38.0 0.149 S -132.2 86.0 38.0 0.149 0.0 HOH
 3.229
 NE1
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 TRP A:107 B:122 38.0 0.149 S -132.5 86.5 38.0 0.149 0.0 HOH
 3.100
 NE1
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 TRP A:79 A:118 41.0 0.161 S -116.7 151.3 41.0 0.161 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 TRP A:79 A:118 45.0 0.176 S -123.2 111.8 45.0 0.176 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 TRP A:98 A:122 41.0 0.161 S -129.8 103.5 41.0 0.161 0.0 HOH
 2.983
 HB3
 O
TRP B:98 B:122 41.0 0.161 S -135.0 86.3 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 TRP A:98 B:122 38.0 0.149 S -137.6 80.7 38.0 0.149 0.0 HOH
 2.055
 HE1
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 TRP A:98 A:122 38.0 0.149 S -130.7 106.1 38.0 0.149 0.0 HOH
 5.764
 CZ2
 O
TRP B:98 B:122 45.0 0.176 S -122.7 81.1 NA NA NA
TRP C:98 C:122 34.0 0.133 S -113.5 99.3 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 TRP A:98 B:122 36.0 0.141 S -122.7 77.8 36.0 0.141 0.0 HOH
 3.924
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 TRP A:117 A:117 37.0 0.145 S -138.4 95.0