Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155599223 . G A CCDS5942.1:NM_000193.2:c.329gCc>gTc_NP_000184.1:p.110A>V Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ALA A:110 G:110 2.0 0.017 H -58.2 -52.3 2.0 0.017 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ALA B:90 B:110 2.0 0.017 H -63.0 -40.8 2.0 0.017 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:87 C:110 1.0 0.009 H -63.1 -31.4 1.0 0.009 0.0
ALA F:87 F:110 1.0 0.009 H -63.1 -31.5 1.0 0.009 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:87 C:110 1.0 0.009 H -63.1 -31.4 1.0 0.009 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:87 C:110 1.0 0.009 H -63.1 -31.4 1.0 0.009 0.0
ALA F:87 F:110 1.0 0.009 H -63.1 -31.5 1.0 0.009 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ALA C:87 C:110 0.0 0.0 H -67.7 -35.9 0.0 0.0 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ALA B:88 C:110 1.0 0.009 H -65.2 -39.2 1.0 0.009 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ALA B:88 C:110 3.0 0.026 H -58.5 -44.7 3.0 0.026 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ALA A:88 A:110 1.0 0.009 H -54.7 -42.4 1.0 0.009 0.0 HOH
 2.873
 O
 O
ALA B:88 B:110 2.0 0.017 H -62.4 -35.0 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ALA B:198 B:110 1.0 0.009 H -68.3 -52.5 1.0 0.009 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ALA C:82 H:110 1.0 0.009 H -54.6 -45.5 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ALA A:82 A:110 1.0 0.009 H -55.8 -40.0 1.0 0.009 0.0 HOH
 2.825
 O
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ALA A:82 A:110 0.0 0.0 H -58.8 -41.5 0.0 0.0 0.0 CL
HOH
 7.675
2.856
 HB3
O
 CL
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ALA A:90 A:111 1.0 0.009 H -55.1 -40.5 1.0 0.009 0.0 HOH
 2.860
 O
 O
ALA B:90 B:111 0.0 0.0 H -56.0 -41.4 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ALA B:86 H:111 0.0 0.0 H -58.9 -47.7 0.0 0.0 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ALA A:78 A:111 1.0 0.009 H -56.9 -36.1 1.0 0.009 0.0 HOH
 1.965
 O
 H2
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ALA A:100 B:115 0.0 0.0 H -57.0 -39.6 0.0 0.0 0.0 HOH
 2.825
 O
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ALA A:74 A:111 1.0 0.009 H -59.9 -39.1 1.0 0.009 0.0 HOH
 2.983
 O
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ALA A:74 A:111 1.0 0.009 H -56.0 -38.1 1.0 0.009 0.0 HOH
 3.603
 CB
 O
ALA B:74 B:111 1.0 0.009 H -54.6 -40.2 1.0 0.009 0.0 HOH
 3.215
 CB
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ALA A:76 A:111 1.0 0.009 H -52.5 -47.6 1.0 0.009 0.0 HOH
 2.845
 O
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ALA A:100 B:115 1.0 0.009 H -52.9 -42.7 1.0 0.009 0.0 HOH
 2.838
 O
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ALA A:100 B:115 1.0 0.009 H -58.6 -37.8 1.0 0.009 0.0 HOH
 2.834
 O
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ALA A:100 B:115 1.0 0.009 H -57.9 -40.3 1.0 0.009 0.0 HOH
 2.864
 O
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ALA A:72 A:111 0.0 0.0 H -49.9 -41.5 0.0 0.0 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ALA A:72 A:111 1.0 0.009 H -63.0 -21.8 1.0 0.009 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:91 A:115 0.0 0.0 H -57.4 -40.9 0.0 0.0 0.0 HOH
 2.844
 O
 O
ALA B:91 B:115 0.0 0.0 H -57.1 -40.1 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:91 B:115 1.0 0.009 H -56.7 -39.8 1.0 0.009 0.0 HOH
 2.892
 HA
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:91 A:115 2.0 0.017 H -54.3 -37.7 2.0 0.017 0.0 HOH
 2.840
 O
 O
ALA B:91 B:115 1.0 0.009 H -56.2 -40.4 NA NA NA
ALA C:91 C:115 0.0 0.0 H -57.1 -39.9 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ALA A:91 B:115 2.0 0.017 H -61.5 -34.5 2.0 0.017 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ALA A:110 A:110 0.0 0.0 H -57.0 -44.0