Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155599239 . T A CCDS5942.1:NM_000193.2:c.313Aag>Tag_NP_000184.1:p.105K>* Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 LYS A:105 G:105 38.0 0.19 H -63.3 -40.6 38.0 0.19 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 LYS B:85 B:105 48.0 0.24 H -70.4 -31.4 48.0 0.24 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 LYS C:82 C:105 50.0 0.25 H -78.2 -38.7 50.0 0.25 0.0
LYS F:82 F:105 50.0 0.25 H -78.1 -38.7 50.0 0.25 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 LYS C:82 C:105 50.0 0.25 H -78.1 -38.7 50.0 0.25 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 LYS C:82 C:105 50.0 0.25 H -78.2 -38.7 50.0 0.25 0.0
LYS F:82 F:105 50.0 0.25 H -78.1 -38.7 50.0 0.25 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 LYS C:82 C:105 54.0 0.27 H -68.6 -33.9 54.0 0.27 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 LYS B:83 C:105 30.0 0.15 H -67.2 -32.7 30.0 0.15 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 LYS B:83 C:105 56.0 0.28 H -73.7 -30.2 56.0 0.28 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 LYS A:83 A:105 47.0 0.235 H -70.0 -35.5 47.0 0.235 0.0 SO4
HOH
 2.964
4.126
 NZ
NZ
 O1
O
LYS B:83 B:105 52.0 0.26 H -71.7 -33.1 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 LYS B:193 B:105 55.0 0.275 H -64.9 -29.9 55.0 0.275 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 LYS C:77 H:105 48.0 0.24 H -69.1 -40.9 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 LYS A:77 A:105 50.0 0.25 H -66.7 -40.4 50.0 0.25 0.0 SO4
HOH
 2.788
2.866
 NZ
NZ
 O2
O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 LYS A:77 A:105 47.0 0.235 H -72.2 -38.4 47.0 0.235 0.0 HOH
 2.067
 HZ2
 O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 LYS A:85 A:106 47.0 0.235 H -76.0 -38.1 47.0 0.235 0.0 HOH
 3.343
 NZ
 O
LYS B:85 B:106 47.0 0.235 H -71.8 -39.5 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 LYS B:81 H:106 49.0 0.245 H -67.6 -40.4 49.0 0.245 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 LYS A:73 A:106 36.0 0.18 H -67.8 -39.4 36.0 0.18 0.0 HOH
 4.019
 N
 H2
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ARG A:95 B:110 69.0 0.307 H -68.1 -39.7 69.0 0.307 0.0 HOH
 2.956
 NE
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 LYS A:69 A:106 50.0 0.25 H -70.2 -36.4 50.0 0.25 0.0 HOH
 2.715
 NZ
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 LYS A:69 A:106 44.0 0.22 H -73.2 -41.1 44.0 0.22 0.0 HOH
 2.970
 NZ
 O
LYS B:69 B:106 43.0 0.215 H -72.9 -41.5 43.0 0.215 0.0 HOH
 4.946
 NZ
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 LYS A:71 A:106 49.0 0.245 H -70.6 -33.9 49.0 0.245 0.0 HOH
 3.474
 NZ
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ARG A:95 B:110 56.0 0.249 H -63.4 -39.8 56.0 0.249 0.0 HOH
 2.742
 NH1
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ARG A:95 B:110 71.0 0.316 H -67.5 -39.0 71.0 0.316 0.0 HOH
 2.941
 NE
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ARG A:95 B:110 61.0 0.271 H -67.1 -40.3 61.0 0.271 0.0 HOH
 2.784
 NH1
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 LYS A:67 A:106 43.0 0.215 H -53.3 -35.7 43.0 0.215 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 LYS A:67 A:106 38.0 0.19 H -59.6 -43.5 38.0 0.19 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:86 A:110 55.0 0.244 H -67.7 -39.4 55.0 0.244 0.0 HOH
 3.061
 HA
 O
ARG B:86 B:110 54.0 0.24 H -68.8 -41.3 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:86 B:110 47.0 0.209 H -65.8 -41.5 47.0 0.209 0.0 HOH
 2.358
 HH12
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:86 A:110 53.0 0.236 H -66.4 -45.3 53.0 0.236 0.0 HOH
 2.797
 NH2
 O
ARG B:86 B:110 59.0 0.262 H -65.2 -38.4 NA NA NA
ARG C:86 C:110 51.0 0.227 H -73.0 -30.0 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:86 B:110 61.0 0.271 H -60.9 -40.0 61.0 0.271 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 LYS A:105 A:105 55.0 0.275 H -66.2 -42.2