Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604519 . G A CCDS5942.1:NM_000193.2:c.298Cag>Tag_NP_000184.1:p.100Q>* Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 GLN A:100 G:100 109.0 0.606 H -53.6 -41.9 41.0 0.228 0.378 B:Q96F81:0.378
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 GLN B:80 B:100 105.0 0.583 H -67.8 -39.2 105.0 0.583 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLN C:77 C:100 67.0 0.372 H -77.7 -43.7 67.0 0.372 0.0
GLN F:77 F:100 69.0 0.383 H -77.6 -43.8 69.0 0.383 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLN C:77 C:100 68.0 0.378 H -77.7 -43.8 68.0 0.378 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLN C:77 C:100 67.0 0.372 H -77.7 -43.7 67.0 0.372 0.0
GLN F:77 F:100 69.0 0.383 H -77.6 -43.8 69.0 0.383 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 GLN C:77 C:100 78.0 0.433 H -70.3 -36.6 78.0 0.433 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 GLN B:78 C:100 100.0 0.556 H -72.8 -37.1 100.0 0.556 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 GLN B:78 C:100 84.0 0.467 H -63.1 -43.2 84.0 0.467 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 GLN A:78 A:100 90.0 0.5 H -56.1 -41.1 90.0 0.5 0.0 SO4
HOH
 8.891
2.774
 O
OE1
 O1
O
GLN B:78 B:100 95.0 0.528 H -58.7 -44.0 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 GLN B:188 B:100 109.0 0.606 H -78.8 -45.0 109.0 0.606 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 GLN C:72 H:100 91.0 0.506 H -55.3 -37.9 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 GLN A:72 A:100 94.0 0.522 H -59.3 -45.1 94.0 0.522 0.0 SO4
HOH
 9.331
2.808
 O
N
 O1
O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 GLN A:72 A:100 85.0 0.472 H -61.8 -40.2 85.0 0.472 0.0 CL
HOH
 8.106
1.667
 OE1
HE21
 CL
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 GLN A:80 A:101 111.0 0.617 H -57.5 -42.4 111.0 0.617 0.0 HOH
 2.809
 N
 O
GLN B:80 B:101 98.0 0.544 H -59.4 -43.2 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 GLN B:76 H:101 84.0 0.467 H -58.3 -43.0 39.0 0.217 0.25 A:Q3TDN0:0.25
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 GLN A:68 A:101 105.0 0.583 H -56.4 -42.2 105.0 0.583 0.0 HOH
 1.934
 H
 O
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 GLN A:90 B:105 93.0 0.517 H -58.6 -43.7 93.0 0.517 0.0 HOH
 2.714
 OE1
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 GLN A:64 A:101 95.0 0.528 H -60.0 -39.4 95.0 0.528 0.0 HOH
 2.726
 OE1
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 GLN A:64 A:101 86.0 0.478 H -53.6 -45.9 86.0 0.478 0.0 HOH
 3.367
 N
 O
GLN B:64 B:101 86.0 0.478 H -55.5 -45.2 86.0 0.478 0.0 HOH
 3.541
 NE2
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 GLN A:66 A:101 92.0 0.511 H -67.7 -43.0 92.0 0.511 0.0 HOH
 2.868
 OE1
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 GLN A:90 B:105 98.0 0.544 H -59.3 -46.7 98.0 0.544 0.0 HOH
 2.943
 OE1
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 GLN A:90 B:105 90.0 0.5 H -59.8 -42.1 90.0 0.5 0.0 HOH
 2.598
 OE1
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 GLN A:90 B:105 84.0 0.467 H -58.1 -43.8 84.0 0.467 0.0 HOH
 2.631
 OE1
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 GLN A:62 A:101 105.0 0.583 H -60.5 -52.1 105.0 0.583 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 GLN A:62 A:101 120.0 0.667 H -51.3 -50.3 120.0 0.667 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:81 A:105 85.0 0.472 H -64.1 -40.0 85.0 0.472 0.0 HOH
 2.146
 H
 O
GLN B:81 B:105 94.0 0.522 H -62.4 -41.1 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:81 B:105 89.0 0.494 H -57.1 -39.9 89.0 0.494 0.0 HOH
 2.087
 H
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:81 A:105 89.0 0.494 H -57.4 -35.6 89.0 0.494 0.0 HOH
 2.757
 OE1
 O
GLN B:81 B:105 95.0 0.528 H -53.1 -50.3 NA NA NA
GLN C:81 C:105 70.0 0.389 H -46.8 -41.9 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:81 B:105 104.0 0.578 H -55.5 -33.6 104.0 0.578 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 GLN A:100 A:100 71.0 0.394 H -57.5 -38.9