Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604570 . C A CCDS5942.1:NM_000193.2:c.247Gac>Tac_NP_000184.1:p.83D>Y Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ASP A:83 G:83 45.0 0.3 T -73.2 -15.9 43.0 0.287 0.013 B:Q96F81:0.013
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ASP B:63 B:83 59.0 0.393 T -71.4 -22.7 59.0 0.393 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASP C:60 C:83 58.0 0.387 T -118.7 8.3 23.0 0.153 0.234 B:Q13635:0.233
ASP F:60 F:83 58.0 0.387 T -118.7 8.3 22.0 0.147 0.24 E:Q13635:0.24
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASP C:60 C:83 55.0 0.367 T -118.7 8.3 20.0 0.133 0.234 B:Q13635:0.233
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASP C:60 C:83 58.0 0.387 T -118.7 8.3 23.0 0.153 0.234 B:Q13635:0.233
ASP F:60 F:83 58.0 0.387 T -118.7 8.3 22.0 0.147 0.24 E:Q13635:0.24
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ASP C:60 C:83 51.0 0.34 T -92.3 0.9 13.0 0.087 0.253 A:Q13635:0.253
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ASP B:61 C:83 66.0 0.44 T -89.8 -13.6 29.0 0.193 0.247 A:Q13635:0.247
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ASP B:61 C:83 82.0 0.547 T -89.4 6.4 51.0 0.34 0.207 A:Q13635:0.207
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ASP A:61 A:83 66.0 0.44 T -92.0 8.9 66.0 0.44 0.0 HOH
 2.655
 O
 O
ASP B:61 B:83 57.0 0.38 T -102.5 18.6 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ASP B:171 B:83 66.0 0.44 T -91.5 7.0 66.0 0.44 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ASP C:55 H:83 58.0 0.387 T -95.7 11.6 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ASP A:55 A:83 60.0 0.4 T -95.8 12.1 60.0 0.4 0.0 HOH
 2.763
 O
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ASP A:55 A:83 56.0 0.373 T -94.1 14.2 56.0 0.373 0.0 CL
HOH
 6.501
2.672
 H
OD1
 CL
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ASP A:63 A:84 56.0 0.373 T -97.5 13.0 56.0 0.373 0.0 HOH
 2.776
 O
 O
ASP B:63 B:84 60.0 0.4 T -85.8 9.8 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ASP B:59 H:84 51.0 0.34 T -77.4 -2.2 51.0 0.34 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ASP A:51 A:84 58.0 0.387 T -88.8 14.9 58.0 0.387 0.0 HOH
 1.828
 O
 H1
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ASP A:73 B:88 59.0 0.393 T -95.2 12.6 59.0 0.393 0.0 SO4
HOH
 6.632
2.727
 N
O
 O4
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASP A:47 A:84 56.0 0.373 T -91.7 6.7 56.0 0.373 0.0 HOH
 2.599
 O
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASP A:47 A:84 55.0 0.367 T -90.6 15.1 55.0 0.367 0.0 HOH
 4.879
 CB
 O
ASP B:47 B:84 55.0 0.367 T -94.5 16.7 55.0 0.367 0.0 HOH
 2.807
 OD1
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ASP A:49 A:84 56.0 0.373 T -86.4 4.7 56.0 0.373 0.0 HOH
 2.812
 O
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ASP A:73 B:88 61.0 0.407 T -95.6 10.8 61.0 0.407 0.0 HOH
 2.611
 OD2
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ASP A:73 B:88 61.0 0.407 T -95.1 13.2 61.0 0.407 0.0 HOH
 2.692
 OD2
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ASP A:73 B:88 57.0 0.38 T -97.9 13.8 57.0 0.38 0.0 HOH
 2.729
 O
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ASP A:45 A:84 49.0 0.327 T -97.2 23.6 49.0 0.327 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ASP A:45 A:84 59.0 0.393 T -91.8 27.9 59.0 0.393 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASP A:64 A:88 56.0 0.373 T -76.1 -5.0 56.0 0.373 0.0 HOH
 2.674
 O
 O
ASP B:64 B:88 52.0 0.347 T -71.0 -4.6 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASP A:64 B:88 57.0 0.38 T -93.1 11.6 57.0 0.38 0.0 HOH
 2.652
 OD2
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASP A:64 A:88 63.0 0.42 T -109.5 19.1 63.0 0.42 0.0 HOH
 2.651
 O
 O
ASP B:64 B:88 60.0 0.4 T -101.7 21.3 NA NA NA
ASP C:64 C:88 56.0 0.373 T -84.4 15.4 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASP A:64 B:88 62.0 0.413 T -102.5 24.2 62.0 0.413 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ASP A:83 A:83 56.0 0.373 T -89.7 1.5