Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604582 . T A CCDS5942.1:NM_000193.2:c.235Aat>Tat_NP_000184.1:p.79N>Y Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ASN A:79 G:79 12.0 0.075 -77.3 -62.6 12.0 0.075 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ASN B:59 B:79 26.0 0.163 -84.8 -43.8 26.0 0.163 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:56 C:79 4.0 0.025 -74.9 100.6 4.0 0.025 0.0
ASN F:56 F:79 3.0 0.019 -74.9 100.6 3.0 0.019 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:56 C:79 3.0 0.019 -74.9 100.7 3.0 0.019 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:56 C:79 4.0 0.025 -74.9 100.6 4.0 0.025 0.0
ASN F:56 F:79 3.0 0.019 -74.9 100.6 3.0 0.019 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ASN C:56 C:79 9.0 0.056 -96.0 122.3 9.0 0.056 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ASN B:57 C:79 0.0 0.0 -116.2 96.6 0.0 0.0 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ASN B:57 C:79 4.0 0.025 -100.9 82.9 4.0 0.025 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ASN A:57 A:79 1.0 0.006 -104.4 113.9 1.0 0.006 0.0 HOH
 4.927
 O
 O
ASN B:57 B:79 2.0 0.013 -84.2 113.9 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ASN B:167 B:79 12.0 0.075 -129.7 120.4 12.0 0.075 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ASN C:51 H:79 2.0 0.013 -85.1 111.9 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ASN A:51 A:79 3.0 0.019 -79.3 118.5 3.0 0.019 0.0 HOH
 3.393
 OD1
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ASN A:51 A:79 0.0 0.0 -106.6 111.4 0.0 0.0 0.0 DMS
CL
HOH
 4.628
4.091
4.686
 H
OD1
O
 H13
CL
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ASN A:59 A:80 5.0 0.031 -85.4 113.8 5.0 0.031 0.0 HOH
 3.777
 OD1
 O
ASN B:59 B:80 7.0 0.044 -91.4 110.6 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ASN B:55 H:80 3.0 0.019 -79.1 129.6 3.0 0.019 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ASN A:47 A:80 3.0 0.019 -103.0 115.1 3.0 0.019 0.0 HOH
 3.097
 HD21
 O
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ASN A:69 B:84 2.0 0.013 -90.1 113.7 2.0 0.013 0.0 SO4
HOH
 6.695
3.166
 O
OD1
 O4
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASN A:43 A:80 3.0 0.019 -102.2 116.4 3.0 0.019 0.0 HOH
 3.248
 OD1
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASN A:43 A:80 4.0 0.025 -87.6 120.2 4.0 0.025 0.0 CL
HOH
 7.450
3.333
 C
OD1
 CL
O
ASN B:43 B:80 4.0 0.025 -88.3 121.1 4.0 0.025 0.0 CL
HOH
 9.275
3.499
 N
OD1
 CL
O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ASN A:45 A:80 3.0 0.019 -91.5 117.8 3.0 0.019 0.0 HOH
 7.029
 OD1
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ASN A:69 B:84 3.0 0.019 -102.0 115.8 3.0 0.019 0.0 HOH
 3.661
 CA
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ASN A:69 B:84 1.0 0.006 -94.1 114.0 1.0 0.006 0.0 HOH
 3.364
 OD1
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ASN A:69 B:84 4.0 0.025 -99.6 115.1 4.0 0.025 0.0 HOH
 3.003
 OD1
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ASN A:41 A:80 5.0 0.031 -108.8 103.1 5.0 0.031 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ASN A:41 A:80 3.0 0.019 -117.2 117.1 3.0 0.019 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:60 A:84 3.0 0.019 -89.2 116.5 3.0 0.019 0.0 HOH
 3.143
 HA
 O
ASN B:60 B:84 7.0 0.044 -85.0 115.6 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:60 B:84 1.0 0.006 -91.5 114.1 1.0 0.006 0.0 HOH
 2.924
 HA
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:60 A:84 1.0 0.006 -109.5 112.3 1.0 0.006 0.0 HOH
 7.228
 OD1
 O
ASN B:60 B:84 2.0 0.013 -93.5 109.4 NA NA NA
ASN C:60 C:84 1.0 0.006 -84.8 117.2 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:60 B:84 2.0 0.013 -98.4 113.4 2.0 0.013 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ASN A:79 A:79 2.0 0.013 -101.7 116.2