Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604611 . T A CCDS5942.1:NM_000193.2:c.206aAc>aTc_NP_000184.1:p.69N>I Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ASN A:69 G:69 151.0 0.944 S -123.5 2.8 151.0 0.944 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ASN B:49 B:69 164.0 1.0 S -105.1 36.3 164.0 1.0 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:46 C:69 136.0 0.85 S -148.6 93.0 136.0 0.85 0.0
ASN F:46 F:69 135.0 0.844 S -148.6 93.0 135.0 0.844 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:46 C:69 137.0 0.856 S -148.6 93.0 137.0 0.856 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:46 C:69 136.0 0.85 S -148.6 93.0 136.0 0.85 0.0
ASN F:46 F:69 135.0 0.844 S -148.6 93.0 135.0 0.844 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ASN C:46 C:69 161.0 1.0 T -98.4 68.6 161.0 1.0 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ASN B:47 C:69 156.0 0.975 T -63.5 -43.1 156.0 0.975 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ASN B:47 C:69 138.0 0.863 S -94.8 -46.7 138.0 0.863 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ASN A:47 A:69 152.0 0.95 T -91.0 40.5 152.0 0.95 0.0 HOH
 5.023
 ND2
 O
ASN B:47 B:69 165.0 1.0 T -88.5 32.0 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ASN B:157 B:69 158.0 0.988 T -115.6 44.3 158.0 0.988 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ASN C:41 H:69 159.0 0.994 T -86.4 7.2 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ASN A:41 A:69 165.0 1.0 T -83.9 23.9 165.0 1.0 0.0 HOH
 4.222
 O
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ASN A:41 A:69 113.0 0.706 T 74.9 5.1 113.0 0.706 0.0 DMS
HOH
 9.442
2.075
 OD1
HD22
 H23
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ASN A:49 A:70 159.0 0.994 T -84.9 3.8 159.0 0.994 0.0 HOH
 2.759
 OD1
 O
ASN B:49 B:70 156.0 0.975 T -94.9 -2.6 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ASN B:45 H:70 144.0 0.9 T -86.5 -7.5 144.0 0.9 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ASN A:37 A:70 152.0 0.95 T -80.4 -15.4 152.0 0.95 0.0 HOH
 2.755
 C
 H2
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 SER A:59 B:74 119.0 1.0 T -89.1 -3.4 119.0 1.0 0.0 GOL
HOH
 5.202
2.935
 O
OG
 O2
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASN A:33 A:70 163.0 1.0 T -105.8 48.9 163.0 1.0 0.0 HOH
 2.564
 OD1
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASN A:33 A:70 160.0 1.0 T -94.8 -0.9 160.0 1.0 0.0 HOH
 2.892
 ND2
 O
ASN B:33 B:70 157.0 0.981 T -91.9 -7.3 157.0 0.981 0.0 CL
HOH
 9.889
5.171
 N
N
 CL
O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ASN A:35 A:70 135.0 0.844 S -89.3 -36.9 135.0 0.844 0.0 HOH
 3.155
 O
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 SER A:59 B:74 114.0 0.991 T -83.9 -11.2 114.0 0.991 0.0 HOH
 4.931
 N
 O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 SER A:59 B:74 118.0 1.0 T -87.1 -4.8 118.0 1.0 0.0 HOH
 3.004
 N
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 SER A:59 B:74 121.0 1.0 T -85.9 -6.7 121.0 1.0 0.0 HOH
 3.101
 N
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ASN A:31 A:70 141.0 0.881 S -75.7 0.7 141.0 0.881 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ASN A:31 A:70 137.0 0.856 S -77.1 -3.9 137.0 0.856 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 SER A:50 A:74 121.0 1.0 T -94.6 0.3 121.0 1.0 0.0 HOH
 2.585
 OG
 O
SER B:50 B:74 116.0 1.0 T -74.9 -0.1 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 SER A:50 B:74 116.0 1.0 T -77.4 4.1 116.0 1.0 0.0 HOH
 2.547
 H
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 SER A:50 A:74 119.0 1.0 T -83.3 8.7 119.0 1.0 0.0 HOH
 2.617
 OG
 O
SER B:50 B:74 117.0 1.0 T -81.7 -17.3 NA NA NA
SER C:50 C:74 123.0 1.0 T -73.5 13.6 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 SER A:50 B:74 108.0 0.939 S -74.5 -19.8 108.0 0.939 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ASN A:69 A:69 146.0 0.912 T -92.2 -1.8