Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604634 . C A CCDS5942.1:NM_000193.2:c.183agG>agT_NP_000184.1:p.61R>S Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ARG A:61 G:61 146.0 0.649 -164.0 162.1 131.0 0.582 0.067 B:Q96F81:0.067
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ARG B:41 B:61 149.0 0.662 -65.7 170.3 149.0 0.662 0.0 SER
 7.749
 N
 OG
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ARG C:38 C:61 138.0 0.613 -91.7 172.6 138.0 0.613 0.0
ARG F:38 F:61 138.0 0.613 -91.6 172.6 138.0 0.613 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ARG C:38 C:61 136.0 0.604 -91.7 172.6 136.0 0.604 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ARG C:38 C:61 138.0 0.613 -91.7 172.6 138.0 0.613 0.0
ARG F:38 F:61 138.0 0.613 -91.6 172.6 138.0 0.613 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ARG C:38 C:61 148.0 0.658 -149.5 161.1 148.0 0.658 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ARG B:39 C:61 152.0 0.676 -67.7 151.9 152.0 0.676 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ARG B:39 C:61 182.0 0.809 -71.6 179.3 182.0 0.809 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ARG A:39 A:61 144.0 0.64 -69.2 148.0 144.0 0.64 0.0 HOH
 2.633
 O
 O
ARG B:39 B:61 207.0 0.92 -74.7 149.5 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ARG B:149 B:61 180.0 0.8 -77.2 -173.5 180.0 0.8 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ARG C:33 H:61 209.0 0.929 -72.4 146.9 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ARG A:33 A:61 210.0 0.933 -64.8 149.7 210.0 0.933 0.0 HOH
 2.818
 O
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ARG A:33 A:61 169.0 0.751 -67.3 152.7 169.0 0.751 0.0 DMS
HOH
 9.889
1.704
 HA
HH11
 O
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ARG A:41 A:62 163.0 0.724 -70.8 155.8 163.0 0.724 0.0 HOH
 2.716
 O
 O
ARG B:41 B:62 166.0 0.738 -64.3 152.0 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ARG B:37 H:62 204.0 0.907 -61.8 133.0 164.0 0.729 0.178 A:Q3TDN0:0.178
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ARG A:29 A:62 134.0 0.596 -62.1 151.2 134.0 0.596 0.0 HOH
 2.233
 O
 H1
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ARG A:51 B:66 133.0 0.591 -73.2 153.3 133.0 0.591 0.0 SO4
HOH
 3.541
2.729
 CD
NE
 O3
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ARG A:25 A:62 159.0 0.707 -67.8 154.8 159.0 0.707 0.0 HOH
 2.577
 NH2
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ARG A:25 A:62 207.0 0.92 -57.8 143.9 207.0 0.92 0.0 HOH
 3.543
 O
 O
ARG B:25 B:62 201.0 0.893 -57.9 143.1 201.0 0.893 0.0 HOH
 9.994
 N
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ARG A:27 A:62 210.0 0.933 -83.3 146.1 210.0 0.933 0.0 HOH
 3.393
 CA
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ARG A:51 B:66 140.0 0.622 -68.5 150.7 140.0 0.622 0.0 SO4
SO4
HOH
 9.623
3.336
2.859
 C
CD
O
 O3
O3
O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ARG A:51 B:66 130.0 0.578 -73.7 151.2 130.0 0.578 0.0 SO4
HOH
 3.125
2.870
 NE
O
 O3
O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ARG A:51 B:66 135.0 0.6 -131.0 150.8 135.0 0.6 0.0 HOH
 2.992
 N
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ARG A:23 A:62 146.0 0.649 -62.4 169.2 146.0 0.649 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ARG A:23 A:62 185.0 0.822 -60.8 159.6 185.0 0.822 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:42 A:66 194.0 0.862 -75.0 153.4 194.0 0.862 0.0 HOH
 2.479
 HG3
 O
ARG B:42 B:66 171.0 0.76 -66.7 152.6 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:42 B:66 167.0 0.742 -74.6 157.4 167.0 0.742 0.0 HOH
 2.186
 H
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:42 A:66 185.0 0.822 -78.8 149.8 185.0 0.822 0.0 HOH
 3.450
 CB
 O
ARG B:42 B:66 165.0 0.733 -69.4 151.4 NA NA NA
ARG C:42 C:66 203.0 0.902 -54.9 149.3 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ARG A:42 B:66 205.0 0.911 -77.5 164.5 205.0 0.911 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ARG A:61 A:61 126.0 0.56 -64.6 155.8