Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604663 . C A CCDS5942.1:NM_000193.2:c.154Gcc>Tcc_NP_000184.1:p.52A>S Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ALA A:52 G:52 68.0 0.591 -52.8 159.2 68.0 0.591 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ALA B:32 B:52 61.0 0.53 -74.2 161.2 61.0 0.53 0.0
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:29 C:52 66.0 0.574 -66.1 148.7 66.0 0.574 0.0
ALA F:29 F:52 64.0 0.557 -66.1 148.7 64.0 0.557 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:29 C:52 65.0 0.565 -66.1 148.7 65.0 0.565 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ALA C:29 C:52 66.0 0.574 -66.1 148.7 66.0 0.574 0.0
ALA F:29 F:52 64.0 0.557 -66.1 148.7 64.0 0.557 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ALA C:29 C:52 56.0 0.487 -70.6 167.4 56.0 0.487 0.0
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ALA B:30 C:52 53.0 0.461 -73.9 165.3 53.0 0.461 0.0
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ALA B:30 C:52 56.0 0.487 -65.0 170.0 56.0 0.487 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ALA A:30 A:52 44.0 0.383 -62.5 143.4 44.0 0.383 0.0 HOH
 2.822
 N
 O
ALA B:30 B:52 65.0 0.565 -68.1 145.5 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ALA B:140 B:52 58.0 0.504 -83.7 163.0 58.0 0.504 0.0
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ALA C:24 H:52 58.0 0.504 -62.1 150.0 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ALA A:24 A:52 60.0 0.522 -58.0 143.1 60.0 0.522 0.0 HOH
 3.603
 CA
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ALA A:24 A:52 62.0 0.539 -64.1 148.1 62.0 0.539 0.0 DMS
DMS
HOH
 5.692
2.285
2.173
 HB1
HA
H
 O
H23
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ALA A:32 A:53 61.0 0.53 -65.5 147.3 61.0 0.53 0.0 HOH
 2.866
 N
 O
ALA B:32 B:53 60.0 0.522 -63.7 141.6 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ALA B:28 H:53 58.0 0.504 -58.4 142.8 58.0 0.504 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ALA A:20 A:53 63.0 0.548 -62.2 146.9 63.0 0.548 0.0 HOH
 2.002
 H
 O
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 PRO A:42 B:57 87.0 0.6 -61.1 148.0 87.0 0.6 0.0 HOH
 3.681
 CB
 O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ALA A:16 A:53 64.0 0.557 -65.1 150.2 64.0 0.557 0.0 HOH
 3.019
 N
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ALA A:16 A:53 65.0 0.565 -67.4 145.8 65.0 0.565 0.0 HOH
 3.542
 CA
 O
ALA B:16 B:53 63.0 0.548 -67.7 145.5 63.0 0.548 0.0 HOH
 2.899
 N
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ALA A:18 A:53 63.0 0.548 -69.7 135.3 63.0 0.548 0.0 HOH
 3.512
 N
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 PRO A:42 B:57 84.0 0.579 -57.1 144.3 84.0 0.579 0.0 SO4
HOH
 9.968
3.299
 CB
CD
 O4
O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 PRO A:42 B:57 87.0 0.6 -61.3 146.8 87.0 0.6 0.0 HOH
 3.586
 CB
 O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 PRO A:42 B:57 87.0 0.6 -60.5 147.5 87.0 0.6 0.0 HOH
 3.422
 CD
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ALA A:14 A:53 65.0 0.565 -63.9 139.8 65.0 0.565 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ALA A:14 A:53 63.0 0.548 -66.0 148.8 63.0 0.548 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 PRO A:33 A:57 84.0 0.579 -63.8 139.2 84.0 0.579 0.0 HOH
 2.848
 HD3
 O
PRO B:33 B:57 87.0 0.6 -63.8 145.0 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 PRO A:33 B:57 86.0 0.593 -64.2 148.7 86.0 0.593 0.0 HOH
 2.788
 HD2
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 PRO A:33 A:57 92.0 0.634 -50.4 150.9 92.0 0.634 0.0 HOH
 3.702
 CB
 O
PRO B:33 B:57 85.0 0.586 -60.9 141.1 NA NA NA
PRO C:33 C:57 83.0 0.572 -68.5 149.2 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 PRO A:33 B:57 84.0 0.579 -54.1 148.8 84.0 0.579 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ALA A:52 A:52 64.0 0.557 -62.7 145.1