Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604668 . T A CCDS5942.1:NM_000193.2:c.149aAt>aTt_NP_000184.1:p.50N>I Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 ASN A:50 G:50 117.0 0.731 S 71.3 5.1 54.0 0.338 0.393 B:Q96F81:0.394
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 ASN B:30 B:50 127.0 0.794 S -83.1 54.5 117.0 0.731 0.063 A:Q13635:0.062
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:27 C:50 133.0 0.831 61.8 19.2 133.0 0.831 0.0
ASN F:27 F:50 133.0 0.831 62.0 19.1 133.0 0.831 0.0
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:27 C:50 132.0 0.825 61.9 19.2 132.0 0.825 0.0
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 ASN C:27 C:50 133.0 0.831 61.8 19.2 133.0 0.831 0.0
ASN F:27 F:50 133.0 0.831 62.0 19.1 133.0 0.831 0.0
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 ASN C:27 C:50 132.0 0.825 S -86.3 52.7 123.0 0.769 0.056 B:Q13635:0.056
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 ASN B:28 C:50 132.0 0.825 S 63.3 31.1 128.0 0.8 0.025 C:Q13635:0.025
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 ASN B:28 C:50 153.0 0.956 S 54.3 39.9 153.0 0.956 0.0
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 ASN A:28 A:50 133.0 0.831 S -85.4 63.4 133.0 0.831 0.0 SO4
HOH
 7.995
2.683
 N
OD1
 O2
O
ASN B:28 B:50 129.0 0.806 S -80.9 55.7 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 ASN B:138 B:50 127.0 0.794 56.3 36.1 121.0 0.756 0.038 A:Q13635+U6GSR1:0.037
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 ASN C:22 H:50 129.0 0.806 S -73.6 51.4 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 ASN A:22 A:50 134.0 0.838 S -80.4 58.5 134.0 0.838 0.0 HOH
 2.713
 O
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 ASN A:22 A:50 125.0 0.781 S -81.1 59.5 125.0 0.781 0.0 DMS
HOH
 6.967
2.262
 C
H
 H23
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 ASN A:30 A:51 126.0 0.787 S -76.6 63.9 126.0 0.787 0.0 HOH
 2.696
 O
 O
ASN B:30 B:51 131.0 0.819 S -78.6 52.5 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 ASN B:26 H:51 138.0 0.863 -79.6 56.2 97.0 0.606 0.257 A:Q3TDN0:0.256
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 ASN A:18 A:51 126.0 0.787 S -75.9 56.7 126.0 0.787 0.0 HOH
 1.862
 H
 O
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 ASN A:40 B:55 137.0 0.856 S -77.4 42.2 137.0 0.856 0.0 SO4
HOH
 4.289
2.714
 N
OD1
 O1
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASN A:14 A:51 133.0 0.831 S -78.8 58.5 133.0 0.831 0.0 HOH
 2.731
 OD1
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 ASN A:14 A:51 127.0 0.794 S -74.8 58.6 127.0 0.794 0.0 HOH
 2.935
 N
 O
ASN B:14 B:51 126.0 0.787 S -77.5 59.3 126.0 0.787 0.0 HOH
 5.333
 O
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 ASN A:16 A:51 123.0 0.769 S -76.2 51.3 123.0 0.769 0.0 HOH
 3.078
 O
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 ASN A:40 B:55 136.0 0.85 S -82.2 58.7 136.0 0.85 0.0 SO4
HOH
 4.414
2.698
 N
OD1
 O1
O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ASN A:40 B:55 132.0 0.825 S -78.9 50.2 132.0 0.825 0.0 SO4
HOH
 4.280
2.520
 N
O
 O1
O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 ASN A:40 B:55 135.0 0.844 S -79.6 51.0 135.0 0.844 0.0 HOH
 2.947
 OD1
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 ASN A:12 A:51 132.0 0.825 S -77.9 46.0 132.0 0.825 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 ASN A:12 A:51 125.0 0.781 S -77.0 54.7 125.0 0.781 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:31 A:55 128.0 0.8 S -88.0 65.7 128.0 0.8 0.0 HOH
 2.084
 HD22
 O
ASN B:31 B:55 135.0 0.844 S -82.0 57.6 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:31 B:55 133.0 0.831 S -86.9 57.5 133.0 0.831 0.0 HOH
 2.112
 H
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:31 A:55 134.0 0.838 S -73.7 35.3 134.0 0.838 0.0 HOH
 3.591
 OD1
 O
ASN B:31 B:55 135.0 0.844 S -76.9 60.1 NA NA NA
ASN C:31 C:55 133.0 0.831 S -79.9 45.9 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 ASN A:31 B:55 135.0 0.844 S -79.8 65.3 135.0 0.844 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 ASN A:50 A:50 140.0 0.875 S -75.8 55.0