Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 155604681 . G A CCDS5942.1:NM_000193.2:c.136Cag>Tag_NP_000184.1:p.46Q>* Homo sapiens sonic hedgehog (SHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7e2i 1 Q15465 100.0 0.0 EM
 2021-12-08 GLN A:46 G:46 85.0 0.472 -132.0 111.9 85.0 0.472 0.0
6dmy 2 Q15465 100.0 7e-128 EM
 2018-07-11 GLN B:26 B:46 59.0 0.328 -135.3 139.6 38.0 0.211 0.117 A:Q13635:0.117
6n7g 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLN C:23 C:46 76.0 0.422 -114.8 148.5 52.0 0.289 0.133 A:Q13635:0.133
GLN F:23 F:46 77.0 0.428 -114.8 148.5 52.0 0.289 0.139 D:Q13635:0.139
6n7h 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLN C:23 C:46 77.0 0.428 -114.8 148.6 52.0 0.289 0.139 A:Q13635:0.139
6n7k 2 Q15465 100.0 7e-128 EM
 2019-05-29 GLN C:23 C:46 76.0 0.422 -114.8 148.5 52.0 0.289 0.133 A:Q13635:0.133
GLN F:23 F:46 77.0 0.428 -114.8 148.5 52.0 0.289 0.139 D:Q13635:0.139
6rvd 2 Q15465 100.0 7e-128 EM
 2019-10-02 GLN C:23 C:46 68.0 0.378 -99.6 153.9 39.0 0.217 0.161 B:Q13635:0.161
6e1h 2 Q15465 100.0 7e-128 EM
 2018-08-29 GLN B:24 C:46 71.0 0.394 -133.7 143.5 37.0 0.206 0.188 C:Q13635:0.189
6oev 2 Q15465 100.0 7e-128 EM
 2019-04-17 GLN B:24 C:46 57.0 0.317 -105.7 145.4 57.0 0.317 0.0 ZN
 9.271
 O
 ZN
3m1n 1 Q15465 100.0 2e-126 X-RAY
 2010-03-16 GLN A:24 A:46 77.0 0.428 -75.0 147.3 77.0 0.428 0.0 SO4
HOH
 5.436
2.836
 NE2
NE2
 O4
O
GLN B:24 B:46 75.0 0.417 -76.6 145.0 NA NA NA
6rmg 2 Q15465 98.31 9e-126 EM
 2019-10-09 GLN B:134 B:46 77.0 0.428 -114.9 132.2 51.0 0.283 0.145 A:Q13635+U6GSR1:0.144
3ho5 2 Q15465 100.0 2e-123 X-RAY
 2009-06-23 GLN C:18 H:46 69.0 0.383 -89.9 136.9 NA NA NA
3mxw 1 Q15465 100.0 2e-123 X-RAY
 2010-05-26 GLN A:18 A:46 73.0 0.406 -75.1 145.6 73.0 0.406 0.0 HOH
 2.687
 OE1
 O
6pjv 1 Q15465 100.0 2e-123 X-RAY
 2019-11-13 GLN A:18 A:46 76.0 0.422 -77.3 150.6 76.0 0.422 0.0 DMS
DMS
HOH
 9.164
7.458
2.155
 O
C
HE22
 H22
O
O
3d1m 1 Q62226 97.62 9e-120 X-RAY
 2008-09-23 GLN A:26 A:47 74.0 0.411 -81.3 145.3 74.0 0.411 0.0 HOH
 2.603
 OE1
 O
GLN B:26 B:47 74.0 0.411 -77.3 146.6 NA NA NA
7rpk 2 Q62226 99.39 1e-119 EM
 2021-10-27 GLN B:22 H:47 76.0 0.422 -74.6 145.7 76.0 0.422 0.0
1vhh 1 Q62226 99.38 1e-117 X-RAY
 1996-01-29 GLN A:14 A:47 76.0 0.422 -78.9 147.7 76.0 0.422 0.0 HOH
 1.942
 HE21
 O
3k7g 1 Q14623 88.07 1e-112 X-RAY
 2011-01-26 GLN A:36 B:51 76.0 0.422 -74.7 146.7 76.0 0.422 0.0 SO4
HOH
 3.539
3.028
 NE2
NE2
 O4
O
4c4m 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 GLN A:10 A:47 78.0 0.433 -76.5 144.0 78.0 0.433 0.0 HOH
 2.976
 NE2
 O
4c4n 1 Q62226 99.36 1e-112 X-RAY
 2013-10-02 GLN A:10 A:47 79.0 0.439 -77.4 140.2 79.0 0.439 0.0 HOH
 3.775
 NE2
 O
GLN B:10 B:47 75.0 0.417 -76.4 140.9 75.0 0.417 0.0 HOH
 4.257
 OE1
 O
3n1r 1 Q62226 99.36 2e-112 X-RAY
 2010-06-02 GLN A:12 A:47 67.0 0.372 -78.1 151.2 67.0 0.372 0.0 HOH
 5.834
 OE1
 O
3k7j 1 Q14623 87.5 4e-112 X-RAY
 2011-01-26 GLN A:36 B:51 71.0 0.394 -80.4 145.5 71.0 0.394 0.0 SO4
HOH
 3.522
2.878
 NE2
NE2
 O4
O
3k7i 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 GLN A:36 B:51 75.0 0.417 -72.7 147.4 75.0 0.417 0.0 SO4
HOH
 3.525
2.994
 NE2
NE2
 O4
O
3k7h 1 Q14623 87.5 5e-112 X-RAY
 2011-01-26 GLN A:36 B:51 82.0 0.456 -70.7 145.4 82.0 0.456 0.0 HOH
 2.997
 NE2
 O
2wg4 1 Q62226 99.35 6e-112 X-RAY
 2009-06-30 GLN A:8 A:47 68.0 0.378 -96.5 148.3 68.0 0.378 0.0
2wfx 1 Q62226 99.34 5e-110 X-RAY
 2009-06-30 GLN A:8 A:47 65.0 0.361 -102.1 148.8 65.0 0.361 0.0
3n1f 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:27 A:51 77.0 0.428 -70.6 144.5 77.0 0.428 0.0 HOH
 2.121
 HE22
 O
GLN B:27 B:51 76.0 0.422 -70.7 146.8 NA NA NA
3n1m 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:27 B:51 74.0 0.411 -71.2 150.0 74.0 0.411 0.0 HOH
 2.300
 HE22
 O
3n1o 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:27 A:51 74.0 0.411 -80.8 145.8 74.0 0.411 0.0 HOH
 3.021
 NE2
 O
GLN B:27 B:51 78.0 0.433 -73.9 154.6 NA NA NA
GLN C:27 C:51 74.0 0.411 -83.6 150.4 NA NA NA
3n1p 1 Q14623 88.17 7e-107 X-RAY
 2010-06-02 GLN A:27 B:51 74.0 0.411 -86.7 154.0 74.0 0.411 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15465-f1 1 Q15465 100.0 0.0 GLN A:46 A:46 79.0 0.439 -85.3 138.6