Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 22768331 | . | T | A | CCDS5375.1:NM_000600.3:c.230aTg>aAg_NP_000591.1:p.77M>K | Homo sapiens interleukin 6 (IL6), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1alu | 1 | P05231 | 100.0 | 1e-137 |
X-RAY |
1998-06-03 | MET | A:51 | A:49 | 30.0 | 0.162 | -95.8 | 10.0 | 30.0 | 0.162 | 0.0 |
SO4 HOH |
4.887 2.900 |
O C |
O3 O |
|||
| 4ni7 | 1 | P05231 | 100.0 | 1e-137 |
X-RAY |
2014-01-22 | MET | A:51 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4ni9 | 2 | P05231 | 100.0 | 1e-137 |
X-RAY |
2014-01-22 | MET | B:51 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| MET | C:51 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4o9h | 1 | P05231 | 100.0 | 1e-137 |
X-RAY |
2015-04-15 | MET | A:51 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 1p9m | 2 | P05231 | 100.0 | 2e-136 |
X-RAY |
2003-07-01 | MET | B:51 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 7nxz | 1 | P05231 | 99.45 | 4e-135 |
X-RAY |
2021-04-07 | NLE | A:48 | AAA:48 | NA | NA | NA | NA | NA | NA | NA | NA |
HOH |
4.584 |
HE3 |
O |
||
| 4cni | 3 | P05231 | 100.0 | 7e-126 |
X-RAY |
2014-04-30 | MET | C:36 | C:49 | 117.0 | 0.632 | T | 64.1 | 18.0 | NA | NA | NA | ||||||
| MET | D:36 | D:49 | 114.0 | 0.616 | T | 59.8 | 37.5 | 114.0 | 0.616 | 0.0 |
SO4 HOH |
7.688 4.608 |
O N |
O1 O |
|||||||||
| 4zs7 | 1 | P05231 | 100.0 | 7e-126 |
X-RAY |
2016-05-04 | MET | A:36 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4j4l | 2 | P05231 | 100.0 | 5e-121 |
X-RAY |
2014-02-12 | MET | C:33 | C:49 | 25.0 | 0.135 | -80.6 | -12.7 | 25.0 | 0.135 | 0.0 |
HOH |
4.651 |
CE |
O |
|||
| MET | D:33 | D:49 | 19.0 | 0.103 | T | -68.6 | -28.9 | NA | NA | NA | |||||||||||||
| 5fuc | 1 | P05231 | 99.39 | 8e-120 |
X-RAY |
2017-01-25 | MET | A:31 | A:49 | 26.0 | 0.141 | -114.4 | 88.3 | 26.0 | 0.141 | 0.0 |
HOH |
5.138 |
N |
O |
|||
| MET | B:31 | B:49 | 20.0 | 0.108 | -103.1 | 112.0 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p05231-f1 | 1 | P05231 | 100.0 | 1e-158 | MET | A:77 | A:77 | 27.0 | 0.146 | T | -72.3 | -6.7 | |