Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 22771025 . G A CCDS5375.1:NM_000600.3:c.472Gca>Aca_NP_000591.1:p.158A>T Homo sapiens interleukin 6 (IL6), mRNA.
pdb_id: 
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label_comp_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1alu 1 P05231 100.0 1e-137 X-RAY
 1998-06-03 ALA A:132 A:130 9.0 0.078 T -89.8 37.5 2.0 0.017 0.061 A:P05231:0.061
 HOH
 7.058
 N
 O
4ni7 1 P05231 100.0 1e-137 X-RAY
 2014-01-22 ALA A:132 A:130 89.0 0.774 -92.7 360.0 89.0 0.774 0.0
4ni9 2 P05231 100.0 1e-137 X-RAY
 2014-01-22 ALA B:132 A:130 96.0 0.835 -102.7 360.0 96.0 0.835 0.0
ALA C:132 C:130 95.0 0.826 -101.1 360.0 95.0 0.826 0.0
4o9h 1 P05231 100.0 1e-137 X-RAY
 2015-04-15 ALA A:132 A:130 13.0 0.113 T -77.2 -1.9 13.0 0.113 0.0 HOH
 7.348
 CA
 O
1p9m 2 P05231 100.0 2e-136 X-RAY
 2003-07-01 ALA B:132 B:130 13.0 0.113 S -116.6 4.4 13.0 0.113 0.0
7nxz 1 P05231 99.45 4e-135 X-RAY
 2021-04-07 ALA A:129 AAA:129 4.0 0.035 T -89.8 9.5 4.0 0.035 0.0 HOH
 6.084
 H
 O
4cni 3 P05231 100.0 7e-126 X-RAY
 2014-04-30 ALA C:117 C:130 9.0 0.078 T -84.4 6.4 NA NA NA
ALA D:117 D:130 26.0 0.226 H -71.6 -78.5 26.0 0.226 0.0 HOH
 3.887
 O
 O
4zs7 1 P05231 100.0 7e-126 X-RAY
 2016-05-04 ALA A:117 A:130 29.0 0.252 S -78.7 -159.5 29.0 0.252 0.0 HOH
 7.818
 CB
 O
4j4l 2 P05231 100.0 5e-121 X-RAY
 2014-02-12 ALA C:114 C:130 33.0 0.287 -108.9 175.4 33.0 0.287 0.0 HOH
 4.496
 CA
 O
ALA D:114 D:130 15.0 0.13 -89.2 134.5 NA NA NA
5fuc 1 P05231 99.39 8e-120 X-RAY
 2017-01-25 ALA A:112 A:130 88.0 0.765 -97.9 360.0 88.0 0.765 0.0
ALA B:112 B:130 19.0 0.165 -86.2 175.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05231-f1 1 P05231 100.0 1e-158 ALA A:158 A:158 16.0 0.139 -71.3 132.3