Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 22771039 . T A CCDS5375.1:NM_000600.3:c.486gaT>gaA_NP_000591.1:p.162D>E Homo sapiens interleukin 6 (IL6), mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1alu 1 P05231 100.0 1e-137 X-RAY
 1998-06-03 ASP A:136 A:134 140.0 0.933 -73.7 179.5 124.0 0.827 0.106 A:P05231:0.107
 HOH
 6.653
 OD2
 O
4ni7 1 P05231 100.0 1e-137 X-RAY
 2014-01-22 ASP A:136 NA:NA DO NA DO DO DO NA NA NA
4ni9 2 P05231 100.0 1e-137 X-RAY
 2014-01-22 ASP B:136 NA:NA DO NA DO DO DO NA NA NA
ASP C:136 NA:NA DO NA DO DO DO NA NA NA
4o9h 1 P05231 100.0 1e-137 X-RAY
 2015-04-15 ASP A:136 A:134 95.0 0.633 -150.7 121.2 95.0 0.633 0.0 HOH
 8.908
 OD2
 O
1p9m 2 P05231 100.0 2e-136 X-RAY
 2003-07-01 ASP B:136 B:134 98.0 0.653 -160.2 -143.1 98.0 0.653 0.0
7nxz 1 P05231 99.45 4e-135 X-RAY
 2021-04-07 ASP A:133 AAA:133 62.0 NA 75.7 -154.2 62.0 NA NA HOH
 5.056
 O
 O
4cni 3 P05231 100.0 7e-126 X-RAY
 2014-04-30 ASP C:121 C:134 149.0 0.993 -65.2 157.6 NA NA NA
ASP D:121 D:134 148.0 0.987 T -61.1 -40.3 148.0 0.987 0.0 HOH
 3.284
 O
 O
4zs7 1 P05231 100.0 7e-126 X-RAY
 2016-05-04 ASP A:121 A:134 156.0 1.0 -143.4 360.0 156.0 1.0 0.0 HOH
 4.427
 CB
 O
4j4l 2 P05231 100.0 5e-121 X-RAY
 2014-02-12 ASP C:118 NA:NA DO NA DO DO DO NA NA NA
ASP D:118 D:134 149.0 0.993 S -97.2 -26.2 NA NA NA
5fuc 1 P05231 99.39 8e-120 X-RAY
 2017-01-25 ASP A:116 A:134 198.0 1.0 360.0 -49.1 198.0 1.0 0.0
ASP B:116 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05231-f1 1 P05231 100.0 1e-158 ASP A:162 A:162 159.0 1.0 T -69.8 -23.0