Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 22771064 | . | A | C | CCDS5375.1:NM_000600.3:c.511Aca>Cca_NP_000591.1:p.171T>P | Homo sapiens interleukin 6 (IL6), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1alu | 1 | P05231 | 100.0 | 1e-137 |
X-RAY |
1998-06-03 | THR | A:145 | A:143 | 85.0 | 0.607 | H | -67.1 | -34.1 | 85.0 | 0.607 | 0.0 |
HOH |
6.041 |
N |
O |
||
4ni7 | 1 | P05231 | 100.0 | 1e-137 |
X-RAY |
2014-01-22 | THR | A:145 | A:143 | 92.0 | 0.657 | H | -58.3 | -41.9 | 92.0 | 0.657 | 0.0 | ||||||
4ni9 | 2 | P05231 | 100.0 | 1e-137 |
X-RAY |
2014-01-22 | THR | B:145 | A:143 | 108.0 | 0.771 | H | -62.8 | -35.8 | 108.0 | 0.771 | 0.0 |
HOH |
7.521 |
C |
O |
||
THR | C:145 | C:143 | 94.0 | 0.671 | T | -93.6 | -28.2 | 94.0 | 0.671 | 0.0 |
HOH |
8.405 |
C |
O |
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4o9h | 1 | P05231 | 100.0 | 1e-137 |
X-RAY |
2015-04-15 | THR | A:145 | A:143 | 90.0 | 0.643 | H | -66.7 | -35.5 | 90.0 | 0.643 | 0.0 |
HOH |
7.289 |
C |
O |
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1p9m | 2 | P05231 | 100.0 | 2e-136 |
X-RAY |
2003-07-01 | THR | B:145 | B:143 | 88.0 | 0.629 | H | -77.7 | -30.1 | 88.0 | 0.629 | 0.0 | ||||||
7nxz | 1 | P05231 | 99.45 | 4e-135 |
X-RAY |
2021-04-07 | THR | A:142 | AAA:142 | 88.0 | 0.629 | H | -75.9 | -39.1 | 88.0 | 0.629 | 0.0 |
HOH |
6.224 |
HG21 |
O |
||
4cni | 3 | P05231 | 100.0 | 7e-126 |
X-RAY |
2014-04-30 | THR | C:130 | C:143 | 89.0 | 0.636 | H | -55.0 | -40.4 | NA | NA | NA | ||||||
THR | D:130 | D:143 | 87.0 | 0.621 | H | -56.7 | -40.2 | 87.0 | 0.621 | 0.0 |
HOH |
3.031 |
O |
O |
|||||||||
4zs7 | 1 | P05231 | 100.0 | 7e-126 |
X-RAY |
2016-05-04 | THR | A:130 | A:143 | 79.0 | 0.564 | H | -60.0 | -53.1 | 79.0 | 0.564 | 0.0 |
HOH |
6.545 |
N |
O |
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4j4l | 2 | P05231 | 100.0 | 5e-121 |
X-RAY |
2014-02-12 | THR | C:127 | C:143 | 85.0 | 0.607 | H | -50.4 | -54.3 | 85.0 | 0.607 | 0.0 |
HOH |
7.139 |
CB |
O |
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THR | D:127 | D:143 | 88.0 | 0.629 | H | -45.8 | -36.0 | NA | NA | NA | |||||||||||||
5fuc | 1 | P05231 | 99.39 | 8e-120 |
X-RAY |
2017-01-25 | THR | A:125 | A:143 | 93.0 | 0.664 | H | -62.3 | -39.1 | 93.0 | 0.664 | 0.0 | ||||||
THR | B:125 | B:143 | 93.0 | 0.664 | H | -62.8 | -37.0 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p05231-f1 | 1 | P05231 | 100.0 | 1e-158 | THR | A:171 | A:171 | 89.0 | 0.636 | H | -61.3 | -43.7 |