Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 44875220 | . | T | A | CCDS5495.1:NM_138635.3:c.233aAa>aTa_NP_619541.1:p.78K>I | Homo sapiens H2A histone family member V (H2AFV), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
3waa | 3 | Q71UI9 | 100.0 | 1e-87 |
X-RAY |
2013-12-18 | LYS | C:81 | C:77 | 194.0 | 0.97 | T | 58.7 | 40.5 | 194.0 | 0.97 | 0.0 |
DC DC DA DC DC DG DC DA DG |
7.737 4.548 2.657 8.336 9.917 7.158 4.699 8.742 9.871 |
NZ NZ NZ NZ O O O O O |
O3' O3' OP2 OP2 N4 O3' OP2 OP2 O6 |
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LYS | G:81 | G:77 | 189.0 | 0.945 | T | 63.5 | 57.8 | 189.0 | 0.945 | 0.0 |
DT DG DC DA DC DA DC DC DT |
7.595 5.168 8.370 9.642 8.264 6.176 4.939 9.135 9.954 |
O O O O NZ NZ NZ NZ O |
O3' OP2 OP2 N6 O3' C3' OP2 OP2 O4 |
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1f66 | 4 | P17317 | 98.43 | 4e-86 |
X-RAY |
2000-11-27 | LYS | E:78 | C:877 | 201.0 | 1.0 | T | 40.6 | 60.3 | 201.0 | 1.0 | 0.0 |
DC DC DA DC DC DG DC DA DG MN HOH |
9.936 6.593 4.523 7.407 8.728 7.605 5.128 8.323 9.869 9.418 3.718 |
NZ NZ CE CD O O O O O O CE |
O3' O3' OP2 OP2 N4 O3' OP2 OP2 O6 MN O |
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LYS | I:78 | G:1077 | 202.0 | 1.0 | T | 53.0 | 58.5 | 202.0 | 1.0 | 0.0 |
DG DC DA DG DC DA DC MN HOH |
7.489 5.032 8.172 9.743 9.204 6.882 9.450 9.579 4.224 |
O O O O NZ NZ O O CD |
O3' OP2 OP2 O6 C3' OP2 N4 MN O |
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7m1x | 5 | P0C0S6 | 98.43 | 4e-86 |
EM |
2021-09-29 | LYS | E:78 | C:877 | 171.0 | 0.855 | T | 59.8 | 45.4 | 171.0 | 0.855 | 0.0 |
DA DT DA DA DG DA |
8.632 6.909 8.104 7.049 4.667 7.663 |
CE CE CD O O O |
C3' OP2 OP2 O3' OP2 OP2 |
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LYS | I:78 | G:1077 | 162.0 | 0.81 | T | 59.1 | 57.2 | 162.0 | 0.81 | 0.0 |
DG DC DA |
7.054 4.997 8.178 |
O O O |
O3' OP1 OP1 |
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3wa9 | 3 | P0C0S5 | 98.43 | 5e-86 |
X-RAY |
2013-12-18 | LYS | C:81 | C:77 | 193.0 | 0.965 | T | 49.9 | 36.7 | 193.0 | 0.965 | 0.0 |
DC DC DA DC DC DG DC DA |
9.625 6.468 4.649 8.167 9.997 7.021 4.583 8.776 |
NZ NZ CD CD O O O O |
O3' O3' OP2 OP2 N4 O3' OP2 OP2 |
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LYS | G:81 | G:77 | 199.0 | 0.995 | T | 58.1 | 47.7 | 199.0 | 0.995 | 0.0 |
DT DG DC DA DC DA DC DC |
7.305 4.845 7.819 9.783 8.078 6.047 5.654 9.430 |
O O O O NZ NZ CE CD |
O3' OP2 OP2 N6 O3' OP2 OP2 OP2 |
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5b31 | 5 | P0C0S5 | 98.43 | 5e-86 |
X-RAY |
2016-08-03 | LYS | G:81 | G:77 | 174.0 | 0.87 | T | 47.7 | 75.0 | 174.0 | 0.87 | 0.0 |
DT DG DC DA DC DT MN HOH |
7.491 5.038 8.192 9.915 9.025 9.956 9.589 7.445 |
O O O O CG O O C |
O3' OP2 OP2 N6 OP2 O4 MN O |
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5b32 | 5 | P0C0S5 | 98.43 | 5e-86 |
X-RAY |
2016-08-03 | LYS | G:81 | G:77 | 197.0 | 0.985 | T | 56.4 | 42.7 | 197.0 | 0.985 | 0.0 |
DT DG DC DC DA DC DC DT |
7.576 5.106 8.985 9.799 6.332 4.711 6.355 9.686 |
O O O CD CE NZ NZ O |
O3' OP2 OP2 O3' C3' OP2 OP2 O4 |
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5b33 | 3 | P0C0S5 | 98.43 | 5e-86 |
X-RAY |
2016-08-03 | LYS | C:81 | C:77 | 195.0 | 0.975 | T | 35.9 | 50.9 | 195.0 | 0.975 | 0.0 |
DC DC DA DC DC DG DC DA DG |
7.970 5.241 3.538 9.290 9.808 7.249 4.759 8.941 9.457 |
NZ NZ NZ CD O O O O O |
O3' O3' OP2 OP2 N4 O3' OP2 OP2 O6 |
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LYS | G:81 | G:77 | 198.0 | 0.99 | T | 43.3 | 43.1 | 198.0 | 0.99 | 0.0 |
DT DG DC DA DC DA DC DC DT |
7.307 4.852 8.561 9.644 8.394 6.068 4.599 9.036 9.939 |
O O O O NZ NZ NZ NZ O |
O3' OP2 OP2 N6 O3' C3' OP2 OP2 O4 |
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6jou | 3 | P0C0S5 | 97.64 | 4e-85 |
X-RAY |
2020-03-25 | LYS | C:81 | C:77 | 188.0 | 0.94 | T | 51.8 | 50.8 | 188.0 | 0.94 | 0.0 |
DC DC DA DC DC DG DC DA DG MN HOH |
8.612 6.668 5.249 9.189 9.490 7.207 4.722 8.480 9.768 9.685 6.683 |
NZ NZ CE CE O O O O O O C |
O3' OP1 OP2 OP2 N4 O3' OP2 OP2 O6 MN O |
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LYS | G:81 | G:77 | 164.0 | 0.82 | T | 50.6 | 51.6 | 164.0 | 0.82 | 0.0 |
DT DG DC DA DC DC HOH |
7.650 5.126 9.009 8.371 6.519 9.804 7.244 |
O O O CD CD CB C |
O3' OP2 OP2 C5' OP2 OP2 O |
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5z30 | 3 | P0C0S5 | 97.64 | 8e-85 |
X-RAY |
2018-07-18 | LYS | C:81 | C:77 | 193.0 | 0.965 | T | 62.1 | 48.2 | 193.0 | 0.965 | 0.0 |
DC DC DA DC DC DG DC DA DG MN |
9.038 6.126 4.010 8.550 9.600 7.188 4.813 8.054 9.710 9.604 |
CE NZ NZ NZ O O O O O O |
O3' O3' OP2 OP2 N4 C3' OP2 OP2 O6 MN |
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LYS | G:81 | G:77 | 201.0 | 1.0 | T | 61.0 | 44.5 | 201.0 | 1.0 | 0.0 |
DT DG DC DA DC DC MN |
7.657 5.485 9.649 7.668 5.755 9.994 7.959 |
O O O CG CE CB O |
O3' OP2 C5 C5' OP2 OP2 MN |
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4cay | 1 | P0C0S5 | 98.18 | 2e-74 |
X-RAY |
2014-01-22 | LYS | A:61 | A:77 | 167.0 | 0.835 | T | 57.5 | 39.0 | 167.0 | 0.835 | 0.0 |
HOH |
2.750 |
O |
O |
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5fug | 1 | P0C0S5 | 99.08 | 4e-74 |
X-RAY |
2016-03-09 | LYS | A:60 | A:77 | 164.0 | 0.82 | -80.8 | 133.4 | NA | NA | NA | |||||||
LYS | D:60 | D:77 | 159.0 | 0.795 | -116.2 | 109.0 | NA | NA | NA | ||||||||||||||
LYS | G:60 | G:77 | 178.0 | 0.89 | -101.1 | 98.5 | 163.0 | 0.815 | 0.075 |
H:P06899:0.075 |
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LYS | J:60 | J:77 | 148.0 | 0.74 | -119.5 | 137.5 | NA | NA | NA | ||||||||||||||
6m4d | 3 | Q71UI9 | 100.0 | 8e-73 |
EM |
2020-09-23 | LYS | C:78 | C:77 | 167.0 | 0.835 | T | 58.6 | 46.5 | 167.0 | 0.835 | 0.0 |
DA DG |
6.640 4.970 |
O O |
O3' OP1 |
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LYS | G:78 | G:77 | 170.0 | 0.85 | T | 58.6 | 46.6 | 170.0 | 0.85 | 0.0 |
DC |
8.593 |
O |
OP2 |
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4nft | 1 | Q16778,P0C0S5 | 98.99 | 1e-65 |
X-RAY |
2014-04-09 | LYS | A:160 | A:157 | 183.0 | 0.915 | T | 65.0 | 9.4 | 183.0 | 0.915 | 0.0 |
HOH |
8.645 |
C |
O |
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LYS | B:160 | B:157 | 183.0 | 0.915 | T | 60.7 | 7.7 | NA | NA | NA | |||||||||||||
LYS | C:160 | C:157 | 183.0 | 0.915 | T | 64.1 | 46.1 | NA | NA | NA | |||||||||||||
LYS | D:160 | D:157 | 184.0 | 0.92 | T | 63.2 | 45.8 | NA | NA | NA | |||||||||||||
5chl | 2 | P0C0S5 | 92.23 | 6e-63 |
X-RAY |
2016-03-09 | LYS | B:151 | B:151 | 149.0 | 0.745 | -72.1 | 130.4 | 149.0 | 0.745 | 0.0 |
HOH |
3.093 |
NZ |
O |
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6k0c | 1 | Q27894,Q27511 | 91.0 | 2e-60 |
X-RAY |
2019-10-09 | LYS | A:159 | D:186 | 89.0 | NA | T | 59.9 | 40.0 | 89.0 | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q71ui9-f1 | 1 | Q71UI9 | 100.0 | 4e-88 | LYS | A:78 | A:78 | 197.0 | 0.985 | T | 56.0 | 33.8 | |
af-p0c0s5-f1 | 1 | P0C0S5 | 98.43 | 2e-86 | LYS | A:78 | A:78 | 196.0 | 0.98 | T | 56.6 | 34.5 |