Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55209994 . G A CCDS5514.1:NM_005228.3:c.104aGt>aAt_NP_005219.2:p.35S>N Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
2021-12-22 SER A:35 A:11 88.0 0.765 -134.4 15.9 75.0 0.652 0.113 B:P01133:0.113
SER C:35 B:11 84.0 0.73 -142.3 29.3 73.0 0.635 0.095 D:P01133:0.096
7sye 1 P00533 99.92 0.0 EM
2021-12-22 SER A:35 A:11 80.0 0.696 -141.1 18.7 72.0 0.626 0.07 C:P01133:0.07
SER B:35 B:11 82.0 0.713 -142.9 28.4 69.0 0.6 0.113 D:P01133:0.113
7sz5 1 P00533 99.92 0.0 EM
2021-12-22 SER A:35 A:11 72.0 0.626 -141.2 26.7 60.0 0.522 0.104 B:P01135:0.104
SER C:35 B:11 77.0 0.67 -140.7 2.3 69.0 0.6 0.07 D:P01135:0.07
7sz7 1 P00533 99.92 0.0 EM
2021-12-15 SER A:35 A:11 92.0 0.8 -137.3 17.6 77.0 0.67 0.13 B:P01135:0.13
SER C:35 B:11 83.0 0.722 -138.7 3.4 74.0 0.643 0.079 D:P01135:0.078
7sz0 1 P00533 99.83 0.0 EM
2021-12-22 SER A:35 A:11 65.0 0.565 98.1 -12.5 60.0 0.522 0.043 B:P01133:0.043
SER C:35 B:11 74.0 0.643 -138.5 32.0 62.0 0.539 0.104 D:P01133:0.104
7sz1 1 P00533 99.83 0.0 EM
2021-12-22 SER A:35 A:11 83.0 0.722 -141.6 21.7 75.0 0.652 0.07 B:P01133:0.07
SER C:35 B:11 85.0 0.739 -140.4 0.7 70.0 0.609 0.13 D:P01133:0.13
5xwd 1 P00533 99.84 0.0 X-RAY
2018-02-28 SER A:35 A:11 73.0 0.635 -146.9 30.3 73.0 0.635 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
2012-02-01 SER A:35 A:11 80.0 0.696 -140.9 39.3 80.0 0.696 0.0 HOH
6.937
O
O
1ivo 1 P00533 100.0 0.0 X-RAY
2002-10-16 SER A:11 A:11 67.0 0.583 -159.9 55.4 57.0 0.496 0.087 C:P01133:0.087
HOH
4.332
N
O
SER B:11 B:11 74.0 0.643 -138.6 53.3 71.0 0.617 0.026 D:P01133:0.026
4uv7 1 P00533 100.0 0.0 X-RAY
2015-10-14 SER A:11 A:11 79.0 0.687 -144.6 74.6 79.0 0.687 0.0 HOH
3.026
OG
O
3b2v 3 P00533 100.0 0.0 X-RAY
2008-02-19 SER C:11 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
2013-08-28 SER A:11 A:11 95.0 0.826 -138.9 55.7 95.0 0.826 0.0
1nql 1 4885199 99.84 0.0 X-RAY
2003-03-11 SER A:11 A:11 89.0 0.774 -132.7 55.8 70.0 0.609 0.165 B:P01133:0.165
4krp 1 P00533 99.84 0.0 X-RAY
2013-08-28 SER A:11 A:11 92.0 0.8 -141.2 51.6 92.0 0.8 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
2005-04-26 SER A:11 A:11 84.0 0.73 -134.2 56.2 84.0 0.73 0.0
6aru 1 P00533 99.68 0.0 X-RAY
2018-08-29 SER A:11 A:11 71.0 0.617 -139.8 38.9 71.0 0.617 0.0
3njp 1 P00533 99.84 0.0 X-RAY
2010-10-13 SER A:11 A:11 87.0 0.757 -154.9 44.6 74.0 0.643 0.114 C:Q6QBS2:0.113
HOH
4.504
OG
O
SER B:11 B:11 80.0 0.696 -151.3 55.3 66.0 0.574 0.122 D:Q6QBS2:0.122
HOH
6.236
O
O
4uip 1 P00533 100.0 0.0 X-RAY
2015-11-25 SER A:10 A:11 82.0 0.713 -149.8 51.0 82.0 0.713 0.0
5wb7 1 P00533 100.0 0.0 X-RAY
2017-10-18 SER A:11 A:11 83.0 0.722 -124.2 52.1 69.0 0.6 0.122 E:O14944:0.122
HOH
7.029
N
O
SER B:11 B:11 78.0 0.678 -140.7 43.0 NA NA NA
SER C:11 C:11 76.0 0.661 -134.3 36.9 NA NA NA
SER D:11 D:11 81.0 0.704 -151.0 23.1 81.0 0.704 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
2017-10-18 SER A:11 A:11 91.0 0.791 -138.5 53.9 91.0 0.791 0.0 HOH
2.736
O
O
SER D:11 D:11 71.0 0.617 -136.5 24.8 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
2003-09-10 SER A:11 A:11 89.0 0.774 -144.8 46.4 74.0 0.643 0.131 C:P01135:0.13
MAN
PT
HOH
9.192
8.571
6.195
O
N
N
O2
PT
O
SER B:11 B:11 93.0 0.809 -141.0 41.2 75.0 0.652 0.157 D:P01135:0.157
PT
CD
HOH
6.728
5.434
3.045
N
CB
O
PT
CD
O
7len 1 P00533 99.8 0.0 X-RAY
2021-11-17 SER A:11 A:11 77.0 0.67 -127.3 28.8 68.0 0.591 0.079 C:O14944:0.078
MAN
9.245
O
O3
SER B:11 B:11 79.0 0.687 -148.5 52.8 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
2021-11-17 SER A:11 A:11 74.0 0.643 -124.5 23.1 69.0 0.6 0.043 C:O14944:0.043
SER B:11 B:11 72.0 0.626 -127.2 28.8 62.0 0.539 0.087 D:O14944:0.087
MAN
9.607
O
O6
7lfs 1 P00533 99.8 0.0 X-RAY
2021-11-17 SER A:11 A:11 71.0 0.617 -122.7 28.9 60.0 0.522 0.095 E:O14944:0.096
MAN
9.810
OG
C6
SER B:11 B:11 81.0 0.704 -127.5 26.1 NA NA NA
SER C:11 C:11 75.0 0.652 -135.7 34.6 NA NA NA
SER D:11 D:11 63.0 0.548 -127.4 26.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 SER A:35 A:35 58.0 0.504 -145.7 29.9