Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 55209994 | . | G | A | CCDS5514.1:NM_005228.3:c.104aGt>aAt_NP_005219.2:p.35S>N | Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7syd | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | SER | A:35 | A:11 | 88.0 | 0.765 | -134.4 | 15.9 | 75.0 | 0.652 | 0.113 |
B:P01133:0.113 |
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SER | C:35 | B:11 | 84.0 | 0.73 | -142.3 | 29.3 | 73.0 | 0.635 | 0.095 |
D:P01133:0.096 |
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7sye | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | SER | A:35 | A:11 | 80.0 | 0.696 | -141.1 | 18.7 | 72.0 | 0.626 | 0.07 |
C:P01133:0.07 |
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SER | B:35 | B:11 | 82.0 | 0.713 | -142.9 | 28.4 | 69.0 | 0.6 | 0.113 |
D:P01133:0.113 |
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7sz5 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | SER | A:35 | A:11 | 72.0 | 0.626 | -141.2 | 26.7 | 60.0 | 0.522 | 0.104 |
B:P01135:0.104 |
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SER | C:35 | B:11 | 77.0 | 0.67 | -140.7 | 2.3 | 69.0 | 0.6 | 0.07 |
D:P01135:0.07 |
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7sz7 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-15 | SER | A:35 | A:11 | 92.0 | 0.8 | -137.3 | 17.6 | 77.0 | 0.67 | 0.13 |
B:P01135:0.13 |
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SER | C:35 | B:11 | 83.0 | 0.722 | -138.7 | 3.4 | 74.0 | 0.643 | 0.079 |
D:P01135:0.078 |
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7sz0 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | SER | A:35 | A:11 | 65.0 | 0.565 | 98.1 | -12.5 | 60.0 | 0.522 | 0.043 |
B:P01133:0.043 |
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SER | C:35 | B:11 | 74.0 | 0.643 | -138.5 | 32.0 | 62.0 | 0.539 | 0.104 |
D:P01133:0.104 |
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7sz1 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | SER | A:35 | A:11 | 83.0 | 0.722 | -141.6 | 21.7 | 75.0 | 0.652 | 0.07 |
B:P01133:0.07 |
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SER | C:35 | B:11 | 85.0 | 0.739 | -140.4 | 0.7 | 70.0 | 0.609 | 0.13 |
D:P01133:0.13 |
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5xwd | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2018-02-28 | SER | A:35 | A:11 | 73.0 | 0.635 | -146.9 | 30.3 | 73.0 | 0.635 | 0.0 | |||||||
3qwq | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | SER | A:35 | A:11 | 80.0 | 0.696 | -140.9 | 39.3 | 80.0 | 0.696 | 0.0 |
HOH |
6.937 |
O |
O |
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1ivo | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | SER | A:11 | A:11 | 67.0 | 0.583 | -159.9 | 55.4 | 57.0 | 0.496 | 0.087 |
C:P01133:0.087 |
HOH |
4.332 |
N |
O |
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SER | B:11 | B:11 | 74.0 | 0.643 | -138.6 | 53.3 | 71.0 | 0.617 | 0.026 |
D:P01133:0.026 |
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4uv7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-10-14 | SER | A:11 | A:11 | 79.0 | 0.687 | -144.6 | 74.6 | 79.0 | 0.687 | 0.0 |
HOH |
3.026 |
OG |
O |
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3b2v | 3 | P00533 | 100.0 | 0.0 |
X-RAY |
2008-02-19 | SER | C:11 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
4kro | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2013-08-28 | SER | A:11 | A:11 | 95.0 | 0.826 | -138.9 | 55.7 | 95.0 | 0.826 | 0.0 | |||||||
1nql | 1 | 4885199 | 99.84 | 0.0 |
X-RAY |
2003-03-11 | SER | A:11 | A:11 | 89.0 | 0.774 | -132.7 | 55.8 | 70.0 | 0.609 | 0.165 |
B:P01133:0.165 |
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4krp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2013-08-28 | SER | A:11 | A:11 | 92.0 | 0.8 | -141.2 | 51.6 | 92.0 | 0.8 | 0.0 | |||||||
1yy9 | 1 | P00533 | 99.51 | 0.0 |
X-RAY |
2005-04-26 | SER | A:11 | A:11 | 84.0 | 0.73 | -134.2 | 56.2 | 84.0 | 0.73 | 0.0 | |||||||
6aru | 1 | P00533 | 99.68 | 0.0 |
X-RAY |
2018-08-29 | SER | A:11 | A:11 | 71.0 | 0.617 | -139.8 | 38.9 | 71.0 | 0.617 | 0.0 | |||||||
3njp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2010-10-13 | SER | A:11 | A:11 | 87.0 | 0.757 | -154.9 | 44.6 | 74.0 | 0.643 | 0.114 |
C:Q6QBS2:0.113 |
HOH |
4.504 |
OG |
O |
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SER | B:11 | B:11 | 80.0 | 0.696 | -151.3 | 55.3 | 66.0 | 0.574 | 0.122 |
D:Q6QBS2:0.122 |
HOH |
6.236 |
O |
O |
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4uip | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-11-25 | SER | A:10 | A:11 | 82.0 | 0.713 | -149.8 | 51.0 | 82.0 | 0.713 | 0.0 | |||||||
5wb7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | SER | A:11 | A:11 | 83.0 | 0.722 | -124.2 | 52.1 | 69.0 | 0.6 | 0.122 |
E:O14944:0.122 |
HOH |
7.029 |
N |
O |
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SER | B:11 | B:11 | 78.0 | 0.678 | -140.7 | 43.0 | NA | NA | NA | ||||||||||||||
SER | C:11 | C:11 | 76.0 | 0.661 | -134.3 | 36.9 | NA | NA | NA | ||||||||||||||
SER | D:11 | D:11 | 81.0 | 0.704 | -151.0 | 23.1 | 81.0 | 0.704 | 0.0 | ||||||||||||||
5wb8 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | SER | A:11 | A:11 | 91.0 | 0.791 | -138.5 | 53.9 | 91.0 | 0.791 | 0.0 |
HOH |
2.736 |
O |
O |
|||
SER | D:11 | D:11 | 71.0 | 0.617 | -136.5 | 24.8 | NA | NA | NA | ||||||||||||||
1mox | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2003-09-10 | SER | A:11 | A:11 | 89.0 | 0.774 | -144.8 | 46.4 | 74.0 | 0.643 | 0.131 |
C:P01135:0.13 |
MAN PT HOH |
9.192 8.571 6.195 |
O N N |
O2 PT O |
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SER | B:11 | B:11 | 93.0 | 0.809 | -141.0 | 41.2 | 75.0 | 0.652 | 0.157 |
D:P01135:0.157 |
PT CD HOH |
6.728 5.434 3.045 |
N CB O |
PT CD O |
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7len | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | SER | A:11 | A:11 | 77.0 | 0.67 | -127.3 | 28.8 | 68.0 | 0.591 | 0.079 |
C:O14944:0.078 |
MAN |
9.245 |
O |
O3 |
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SER | B:11 | B:11 | 79.0 | 0.687 | -148.5 | 52.8 | NA | NA | NA | ||||||||||||||
7lfr | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | SER | A:11 | A:11 | 74.0 | 0.643 | -124.5 | 23.1 | 69.0 | 0.6 | 0.043 |
C:O14944:0.043 |
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SER | B:11 | B:11 | 72.0 | 0.626 | -127.2 | 28.8 | 62.0 | 0.539 | 0.087 |
D:O14944:0.087 |
MAN |
9.607 |
O |
O6 |
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7lfs | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | SER | A:11 | A:11 | 71.0 | 0.617 | -122.7 | 28.9 | 60.0 | 0.522 | 0.095 |
E:O14944:0.096 |
MAN |
9.810 |
OG |
C6 |
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SER | B:11 | B:11 | 81.0 | 0.704 | -127.5 | 26.1 | NA | NA | NA | ||||||||||||||
SER | C:11 | C:11 | 75.0 | 0.652 | -135.7 | 34.6 | NA | NA | NA | ||||||||||||||
SER | D:11 | D:11 | 63.0 | 0.548 | -127.4 | 26.1 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00533-f1 | 1 | P00533 | 100.0 | 0.0 | SER | A:35 | A:35 | 58.0 | 0.504 | -145.7 | 29.9 |