Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 55210023 | . | G | A | CCDS5514.1:NM_005228.3:c.133Gaa>Aaa_NP_005219.2:p.45E>K | Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 7syd | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLU | A:45 | A:21 | 111.0 | 0.584 | H | -90.9 | -18.6 | 111.0 | 0.584 | 0.0 | ||||||
| GLU | C:45 | B:21 | 119.0 | 0.626 | H | -97.7 | -25.7 | 119.0 | 0.626 | 0.0 | |||||||||||||
| 7sye | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLU | A:45 | A:21 | 103.0 | 0.542 | H | -85.3 | -32.6 | 103.0 | 0.542 | 0.0 | ||||||
| GLU | B:45 | B:21 | 103.0 | 0.542 | H | -63.7 | -42.1 | 103.0 | 0.542 | 0.0 | |||||||||||||
| 7sz5 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLU | A:45 | A:21 | 86.0 | 0.453 | H | -93.5 | -32.3 | 86.0 | 0.453 | 0.0 | ||||||
| GLU | C:45 | B:21 | 93.0 | 0.489 | H | -91.8 | -43.8 | 93.0 | 0.489 | 0.0 | |||||||||||||
| 7sz7 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-15 | GLU | A:45 | A:21 | 111.0 | 0.584 | H | -91.1 | 12.2 | 111.0 | 0.584 | 0.0 | ||||||
| GLU | C:45 | B:21 | 111.0 | 0.584 | H | -99.9 | -12.3 | 111.0 | 0.584 | 0.0 | |||||||||||||
| 7sz0 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | GLU | A:45 | A:21 | 104.0 | 0.547 | H | -100.5 | 1.8 | 104.0 | 0.547 | 0.0 | ||||||
| GLU | C:45 | B:21 | 107.0 | 0.563 | H | -98.1 | -18.7 | 107.0 | 0.563 | 0.0 | |||||||||||||
| 7sz1 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | GLU | A:45 | A:21 | 139.0 | 0.732 | H | -68.6 | -24.2 | 139.0 | 0.732 | 0.0 | ||||||
| GLU | C:45 | B:21 | 93.0 | 0.489 | H | -85.8 | -42.3 | 93.0 | 0.489 | 0.0 | |||||||||||||
| 5xwd | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2018-02-28 | GLU | A:45 | A:21 | 118.0 | 0.621 | H | -73.6 | -41.3 | 118.0 | 0.621 | 0.0 |
ZN |
2.271 |
OE2 |
ZN |
||
| 3qwq | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | GLU | A:45 | A:21 | 104.0 | 0.547 | H | -68.3 | -48.1 | 104.0 | 0.547 | 0.0 |
HOH |
5.057 |
N |
O |
||
| 1ivo | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | GLU | A:21 | A:21 | 125.0 | 0.658 | H | -77.8 | -57.1 | 125.0 | 0.658 | 0.0 |
HOH |
4.721 |
N |
O |
||
| GLU | B:21 | B:21 | 104.0 | 0.547 | T | -84.1 | -56.0 | 104.0 | 0.547 | 0.0 |
HOH |
4.794 |
OE1 |
O |
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| 4uv7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-10-14 | GLU | A:21 | A:21 | 122.0 | 0.642 | H | -73.3 | -45.2 | 122.0 | 0.642 | 0.0 | ||||||
| 3b2v | 3 | P00533 | 100.0 | 0.0 |
X-RAY |
2008-02-19 | GLU | C:21 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4kro | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2013-08-28 | GLU | A:21 | A:21 | 68.0 | NA | H | -67.0 | -50.0 | 68.0 | NA | NA | ||||||
| 1nql | 1 | 4885199 | 99.84 | 0.0 |
X-RAY |
2003-03-11 | GLU | A:21 | A:21 | 110.0 | 0.579 | H | -60.6 | -58.5 | 110.0 | 0.579 | 0.0 | ||||||
| 4krp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2013-08-28 | GLU | A:21 | A:21 | 71.0 | NA | H | -77.5 | -42.3 | 71.0 | NA | NA | ||||||
| 1yy9 | 1 | P00533 | 99.51 | 0.0 |
X-RAY |
2005-04-26 | GLU | A:21 | A:21 | 89.0 | 0.468 | H | -50.6 | -61.7 | 89.0 | 0.468 | 0.0 |
HOH |
4.802 |
N |
O |
||
| 6aru | 1 | P00533 | 99.68 | 0.0 |
X-RAY |
2018-08-29 | GLU | A:21 | A:21 | 114.0 | 0.6 | H | -69.2 | -45.7 | 114.0 | 0.6 | 0.0 | ||||||
| 3njp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2010-10-13 | GLU | A:21 | A:21 | 120.0 | 0.632 | H | -66.4 | -54.4 | 120.0 | 0.632 | 0.0 |
NAG |
5.838 |
OE2 |
O3 |
||
| GLU | B:21 | B:21 | 110.0 | 0.579 | H | -71.3 | -47.0 | 110.0 | 0.579 | 0.0 | |||||||||||||
| 4uip | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-11-25 | GLU | A:20 | A:21 | 107.0 | 0.563 | H | -68.9 | -36.4 | 107.0 | 0.563 | 0.0 | ||||||
| 5wb7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | GLU | A:21 | A:21 | 85.0 | 0.447 | H | -71.1 | -54.7 | 85.0 | 0.447 | 0.0 | ||||||
| GLU | B:21 | B:21 | 87.0 | 0.458 | H | -70.5 | -44.5 | NA | NA | NA | |||||||||||||
| GLU | C:21 | C:21 | 110.0 | 0.579 | H | -58.6 | -55.5 | NA | NA | NA | |||||||||||||
| GLU | D:21 | D:21 | 110.0 | 0.579 | H | -66.2 | -54.9 | 110.0 | 0.579 | 0.0 | |||||||||||||
| 5wb8 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | GLU | A:21 | A:21 | 91.0 | 0.479 | H | -65.3 | -39.6 | 91.0 | 0.479 | 0.0 |
NAG |
9.325 |
O |
C8 |
||
| GLU | D:21 | D:21 | 99.0 | 0.521 | H | -61.8 | -50.4 | NA | NA | NA | |||||||||||||
| 1mox | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2003-09-10 | GLU | A:21 | A:21 | 112.0 | 0.589 | H | -58.3 | -49.7 | 112.0 | 0.589 | 0.0 |
HOH |
9.272 |
N |
O |
||
| GLU | B:21 | B:21 | 93.0 | 0.489 | H | -59.6 | -45.2 | 93.0 | 0.489 | 0.0 |
HOH |
4.608 |
N |
O |
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| 7len | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLU | A:21 | A:21 | 99.0 | 0.521 | H | -62.9 | -59.2 | 99.0 | 0.521 | 0.0 | ||||||
| GLU | B:21 | B:21 | 104.0 | 0.547 | H | -43.8 | -85.0 | NA | NA | NA | |||||||||||||
| 7lfr | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLU | A:21 | A:21 | 84.0 | 0.442 | H | -44.0 | -60.5 | 84.0 | 0.442 | 0.0 | ||||||
| GLU | B:21 | B:21 | 111.0 | 0.584 | H | -67.7 | -42.7 | 111.0 | 0.584 | 0.0 | |||||||||||||
| 7lfs | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLU | A:21 | A:21 | 83.0 | 0.437 | H | -67.1 | -40.4 | 83.0 | 0.437 | 0.0 | ||||||
| GLU | B:21 | B:21 | 101.0 | 0.532 | H | -66.4 | -46.7 | NA | NA | NA | |||||||||||||
| GLU | C:21 | C:21 | 103.0 | 0.542 | H | -62.8 | -42.5 | NA | NA | NA | |||||||||||||
| GLU | D:21 | D:21 | 103.0 | 0.542 | H | -64.3 | -45.4 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p00533-f1 | 1 | P00533 | 100.0 | 0.0 | GLU | A:45 | A:45 | 119.0 | 0.626 | H | -75.8 | -45.2 | |