Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55210051 . T A CCDS5514.1:NM_005228.3:c.161aTg>aAg_NP_005219.2:p.54M>K Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 MET A:54 A:30 64.0 0.346 H -75.5 -46.6 55.0 0.297 0.049 B:P01133:0.049
MET C:54 B:30 65.0 0.351 H -95.0 -47.5 57.0 0.308 0.043 D:P01133:0.043
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 MET A:54 A:30 63.0 0.341 H -76.4 -59.3 63.0 0.341 0.0
MET B:54 B:30 71.0 0.384 H -78.3 -42.7 53.0 0.286 0.098 D:P01133:0.097
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 MET A:54 A:30 48.0 0.259 H -91.1 -37.5 43.0 0.232 0.027 B:P01135:0.027
MET C:54 B:30 66.0 0.357 H -55.6 -53.8 45.0 0.243 0.114 D:P01135:0.114
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 MET A:54 A:30 62.0 0.335 H -85.9 -37.8 59.0 0.319 0.016 B:P01135:0.016
MET C:54 B:30 54.0 0.292 H -106.9 -53.9 54.0 0.292 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 MET A:54 A:30 65.0 0.351 H -104.4 -40.4 63.0 0.341 0.01 B:P01133:0.011
MET C:54 B:30 74.0 0.4 T -101.5 -50.4 58.0 0.314 0.086 D:P01133:0.086
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 MET A:54 A:30 66.0 0.357 H -70.1 -39.4 57.0 0.308 0.049 B:P01133:0.049
MET C:54 B:30 61.0 0.33 T -118.6 -27.8 56.0 0.303 0.027 D:P01133:0.027
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 MET A:54 A:30 61.0 0.33 H -77.2 -46.3 61.0 0.33 0.0 NAG
 8.545
 N
 O7
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 MET A:54 A:30 65.0 0.351 H -65.7 -51.1 65.0 0.351 0.0 NAG
FUC
 9.071
7.002
 C
O
 C1
C6
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 MET A:30 A:30 57.0 0.308 H -73.4 -55.3 48.0 0.259 0.049 C:P01133:0.049
 NAG
HOH
 7.619
3.225
 N
CE
 O5
O
MET B:30 B:30 51.0 0.276 H -78.4 -53.8 43.0 0.232 0.044 D:P01133:0.043
 NAG
HOH
 5.775
5.932
 N
CE
 O7
O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 MET A:30 A:30 76.0 0.411 H -60.0 -60.2 76.0 0.411 0.0 HOH
 8.380
 SD
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 MET C:30 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 MET A:30 A:30 65.0 0.351 H -69.6 -49.4 65.0 0.351 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 MET A:30 A:30 72.0 0.389 H -81.9 -49.3 63.0 0.341 0.048 B:P01133:0.049
 NAG
 7.844
 N
 O7
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 MET A:30 A:30 65.0 0.351 H -76.9 -52.8 65.0 0.351 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 MET A:30 A:30 62.0 0.335 H -67.1 -54.4 62.0 0.335 0.0 NAG
 8.067
 N
 O6
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 MET A:30 A:30 61.0 0.33 H -65.8 -52.9 61.0 0.33 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 MET A:30 A:30 62.0 0.335 H -70.3 -52.9 49.0 0.265 0.07 C:Q6QBS2:0.07
 NAG
 8.654
 N
 C1
MET B:30 B:30 65.0 0.351 H -87.3 -34.5 46.0 0.249 0.102 D:Q6QBS2:0.103
 NAG
 7.093
 N
 O7
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 MET A:29 A:30 75.0 0.405 H -92.3 -27.9 75.0 0.405 0.0 HOH
 9.428
 N
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 MET A:30 A:30 63.0 0.341 H -77.8 -36.8 48.0 0.259 0.082 E:O14944:0.081
 NAG
HOH
 7.167
8.090
 N
CE
 O7
O
MET B:30 B:30 68.0 0.368 H -73.8 -32.6 NA NA NA
MET C:30 C:30 52.0 0.281 H -77.7 -49.2 NA NA NA
MET D:30 D:30 56.0 0.303 H -65.3 -58.2 56.0 0.303 0.0 NAG
 6.581
 N
 C8
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 MET A:30 A:30 53.0 0.286 H -93.2 -43.4 53.0 0.286 0.0 NAG
HOH
 6.261
3.379
 N
O
 C8
O
MET D:30 D:30 39.0 0.211 H -81.9 -56.9 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 MET A:30 A:30 76.0 0.411 H -78.1 -14.5 57.0 0.308 0.103 C:P01135:0.103
 NAG
PT
HOH
 6.678
2.301
2.589
 N
SD
CE
 O7
PT
O
MET B:30 B:30 96.0 0.519 H -69.6 -21.1 52.0 0.281 0.238 D:P01135:0.238
 NAG
PT
CD
HOH
 6.998
2.032
9.251
3.698
 N
SD
CE
CE
 O7
PT
CD
O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 MET A:30 A:30 52.0 0.281 H -64.2 -55.3 43.0 0.232 0.049 C:O14944:0.049
MET B:30 B:30 55.0 0.297 H -85.3 -45.5 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 MET A:30 A:30 47.0 0.254 H -76.3 -50.6 36.0 0.195 0.059 C:O14944:0.059
MET B:30 B:30 30.0 0.162 H -71.8 -47.8 30.0 0.162 0.0 NAG
 7.061
 N
 C8
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 MET A:30 A:30 67.0 0.362 H -66.9 -40.3 67.0 0.362 0.0 NAG
 8.423
 N
 C8
MET B:30 B:30 67.0 0.362 H -70.5 -38.7 NA NA NA
MET C:30 C:30 49.0 0.265 H -72.3 -46.9 NA NA NA
MET D:30 D:30 62.0 0.335 H -73.5 -54.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 MET A:54 A:54 39.0 0.211 H -59.1 -39.5