Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 55210101 | . | C | A | CCDS5514.1:NM_005228.3:c.211Cag>Aag_NP_005219.2:p.71Q>K | Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7syd | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLN | A:71 | A:47 | 49.0 | 0.272 | -81.4 | -176.0 | 49.0 | 0.272 | 0.0 | |||||||
GLN | C:71 | B:47 | 51.0 | 0.283 | -93.8 | 172.1 | 51.0 | 0.283 | 0.0 | ||||||||||||||
7sye | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLN | A:71 | A:47 | 49.0 | 0.272 | -82.2 | -175.2 | 49.0 | 0.272 | 0.0 | |||||||
GLN | B:71 | B:47 | 53.0 | 0.294 | -86.5 | 168.1 | 53.0 | 0.294 | 0.0 | ||||||||||||||
7sz5 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLN | A:71 | A:47 | 45.0 | 0.25 | -116.5 | 170.4 | 45.0 | 0.25 | 0.0 | |||||||
GLN | C:71 | B:47 | 45.0 | 0.25 | -70.5 | 178.5 | 45.0 | 0.25 | 0.0 | ||||||||||||||
7sz7 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-15 | GLN | A:71 | A:47 | 50.0 | 0.278 | -73.5 | -175.9 | 50.0 | 0.278 | 0.0 | |||||||
GLN | C:71 | B:47 | 36.0 | 0.2 | -39.8 | 147.6 | 36.0 | 0.2 | 0.0 | ||||||||||||||
7sz0 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | GLN | A:71 | A:47 | 41.0 | 0.228 | -67.0 | 168.1 | 41.0 | 0.228 | 0.0 | |||||||
GLN | C:71 | B:47 | 52.0 | 0.289 | -65.8 | 173.7 | 52.0 | 0.289 | 0.0 | ||||||||||||||
7sz1 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | GLN | A:71 | A:47 | 65.0 | 0.361 | -134.0 | -179.9 | 65.0 | 0.361 | 0.0 | |||||||
GLN | C:71 | B:47 | 62.0 | 0.344 | -85.6 | 171.2 | 62.0 | 0.344 | 0.0 | ||||||||||||||
5xwd | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2018-02-28 | GLN | A:71 | A:47 | 51.0 | 0.283 | -84.3 | 174.3 | 51.0 | 0.283 | 0.0 | |||||||
3qwq | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | GLN | A:71 | A:47 | 50.0 | 0.278 | -74.7 | 155.2 | 49.0 | 0.272 | 0.006 |
B:None:0.006 |
HOH |
2.793 |
N |
O |
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1ivo | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | GLN | A:47 | A:47 | 32.0 | 0.178 | -94.8 | -177.3 | 32.0 | 0.178 | 0.0 |
HOH |
2.819 |
N |
O |
|||
GLN | B:47 | B:47 | 55.0 | 0.306 | -77.6 | 172.5 | 55.0 | 0.306 | 0.0 | ||||||||||||||
4uv7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-10-14 | GLN | A:47 | A:47 | 50.0 | 0.278 | -99.4 | 165.2 | 50.0 | 0.278 | 0.0 | |||||||
3b2v | 3 | P00533 | 100.0 | 0.0 |
X-RAY |
2008-02-19 | GLN | C:47 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
4kro | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2013-08-28 | GLN | A:47 | A:47 | 44.0 | NA | -69.5 | -178.9 | 44.0 | NA | NA | |||||||
1nql | 1 | 4885199 | 99.84 | 0.0 |
X-RAY |
2003-03-11 | GLN | A:47 | A:47 | 55.0 | 0.306 | -91.6 | 174.3 | 55.0 | 0.306 | 0.0 | |||||||
4krp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2013-08-28 | GLN | A:47 | A:47 | 38.0 | NA | -83.1 | 174.8 | 38.0 | NA | NA | |||||||
1yy9 | 1 | P00533 | 99.51 | 0.0 |
X-RAY |
2005-04-26 | GLN | A:47 | A:47 | 39.0 | 0.217 | -90.9 | 172.1 | 39.0 | 0.217 | 0.0 |
HOH |
2.698 |
NE2 |
O |
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6aru | 1 | P00533 | 99.68 | 0.0 |
X-RAY |
2018-08-29 | GLN | A:47 | A:47 | 39.0 | 0.217 | -77.0 | 157.0 | 39.0 | 0.217 | 0.0 | |||||||
3njp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2010-10-13 | GLN | A:47 | A:47 | 37.0 | 0.206 | -80.1 | 175.1 | 37.0 | 0.206 | 0.0 |
NAG HOH |
6.197 6.506 |
CB O |
O6 O |
|||
GLN | B:47 | B:47 | 42.0 | 0.233 | -89.1 | 172.3 | 42.0 | 0.233 | 0.0 | ||||||||||||||
4uip | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-11-25 | GLN | A:46 | A:47 | 49.0 | 0.272 | -100.5 | 174.1 | 49.0 | 0.272 | 0.0 | |||||||
5wb7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | GLN | A:47 | A:47 | 55.0 | 0.306 | -94.8 | 170.9 | 55.0 | 0.306 | 0.0 | |||||||
GLN | B:47 | B:47 | 49.0 | 0.272 | -94.2 | 172.2 | NA | NA | NA | ||||||||||||||
GLN | C:47 | C:47 | 41.0 | 0.228 | -104.9 | 164.5 | NA | NA | NA | ||||||||||||||
GLN | D:47 | D:47 | 43.0 | 0.239 | -99.3 | 166.1 | 43.0 | 0.239 | 0.0 | ||||||||||||||
5wb8 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | GLN | A:47 | A:47 | 28.0 | 0.156 | -112.7 | 159.9 | 28.0 | 0.156 | 0.0 |
HOH |
6.892 |
O |
O |
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GLN | D:47 | D:47 | 45.0 | 0.25 | -86.0 | -178.8 | NA | NA | NA | ||||||||||||||
1mox | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2003-09-10 | GLN | A:47 | A:47 | 41.0 | 0.228 | -92.2 | 176.4 | 41.0 | 0.228 | 0.0 |
HOH |
4.551 |
O |
O |
|||
GLN | B:47 | B:47 | 43.0 | 0.239 | -92.2 | 167.4 | 43.0 | 0.239 | 0.0 |
HOH |
2.943 |
N |
O |
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7len | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLN | A:47 | A:47 | 65.0 | 0.361 | -79.5 | 158.5 | 65.0 | 0.361 | 0.0 | |||||||
GLN | B:47 | B:47 | 48.0 | 0.267 | -97.1 | 174.7 | NA | NA | NA | ||||||||||||||
7lfr | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLN | A:47 | A:47 | 94.0 | 0.522 | -79.5 | 163.1 | 94.0 | 0.522 | 0.0 | |||||||
GLN | B:47 | B:47 | 42.0 | 0.233 | -96.3 | 177.1 | 42.0 | 0.233 | 0.0 | ||||||||||||||
7lfs | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLN | A:47 | A:47 | 55.0 | 0.306 | -111.5 | 158.3 | 55.0 | 0.306 | 0.0 | |||||||
GLN | B:47 | B:47 | 74.0 | 0.411 | -77.1 | 166.1 | NA | NA | NA | ||||||||||||||
GLN | C:47 | C:47 | 41.0 | 0.228 | -86.1 | 155.6 | NA | NA | NA | ||||||||||||||
GLN | D:47 | D:47 | 64.0 | 0.356 | -84.9 | 166.6 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00533-f1 | 1 | P00533 | 100.0 | 0.0 | GLN | A:71 | A:71 | 50.0 | 0.278 | -83.9 | 165.3 |