Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55211050 . G A CCDS5514.1:NM_005228.3:c.293cGa>cAa_NP_005219.2:p.98R>Q Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:98 A:74 NA NA NA NA NA NA NA NA
ARG C:98 B:74 81.0 0.36 B -137.7 131.5 81.0 0.36 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:98 A:74 87.0 0.387 B -144.3 137.7 87.0 0.387 0.0
ARG B:98 B:74 120.0 0.533 B -129.0 103.9 120.0 0.533 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:98 A:74 85.0 0.378 B -127.0 122.1 85.0 0.378 0.0
ARG C:98 B:74 78.0 0.347 B -149.0 175.7 78.0 0.347 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ARG A:98 A:74 102.0 0.453 B -142.8 127.6 102.0 0.453 0.0
ARG C:98 B:74 80.0 0.356 B -128.6 133.2 80.0 0.356 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:98 A:74 NA NA NA NA NA NA NA NA
ARG C:98 B:74 NA NA NA NA NA NA NA NA
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:98 A:74 97.0 0.431 -44.1 138.1 97.0 0.431 0.0
ARG C:98 B:74 101.0 0.449 B -140.6 125.9 101.0 0.449 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ARG A:98 A:74 85.0 0.378 B -126.5 122.2 85.0 0.378 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ARG A:98 A:74 84.0 0.373 B -131.7 134.8 84.0 0.373 0.0 HOH
 3.212
 O
 O
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ARG A:74 A:74 119.0 0.529 B -141.1 134.5 119.0 0.529 0.0
ARG B:74 B:74 71.0 0.316 B -124.2 119.6 71.0 0.316 0.0 HOH
 3.120
 NH1
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ARG A:74 A:74 98.0 0.436 B -125.0 132.4 98.0 0.436 0.0 HOH
 9.681
 NH1
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ARG C:74 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ARG A:74 A:74 51.0 NA B -120.3 144.0 51.0 NA NA
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ARG A:74 A:74 94.0 0.418 B -141.6 119.0 94.0 0.418 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ARG A:74 A:74 47.0 NA B -127.7 136.1 47.0 NA NA
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ARG A:74 A:74 78.0 0.347 B -115.3 141.9 78.0 0.347 0.0 HOH
 5.056
 N
 O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ARG A:74 A:74 83.0 0.369 B -132.6 134.3 83.0 0.369 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ARG A:74 A:74 NA NA NA NA NA NA NA NA HOH
 4.582
 N
 O
ARG B:74 B:74 144.0 0.64 B -129.5 132.4 144.0 0.64 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ARG A:73 A:74 89.0 0.396 B -139.9 139.5 89.0 0.396 0.0
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ARG A:74 A:74 88.0 0.391 B -130.7 125.0 88.0 0.391 0.0
ARG B:74 B:74 88.0 0.391 B -125.7 126.6 NA NA NA
ARG C:74 C:74 95.0 0.422 B -126.6 125.2 NA NA NA
ARG D:74 D:74 89.0 0.396 B -129.2 127.0 89.0 0.396 0.0 HOH
 4.712
 NH2
 O
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ARG A:74 A:74 80.0 0.356 B -135.7 139.7 80.0 0.356 0.0 HOH
 4.805
 NH2
 O
ARG D:74 D:74 77.0 0.342 B -133.0 127.0 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 ARG A:74 A:74 72.0 0.32 B -139.4 137.9 72.0 0.32 0.0 HOH
 2.357
 NH2
 O
ARG B:74 B:74 83.0 0.369 B -130.0 131.8 83.0 0.369 0.0 HOH
 7.430
 NE
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:74 A:74 105.0 0.467 B -140.0 138.5 105.0 0.467 0.0
ARG B:74 B:74 119.0 0.529 B -124.1 142.2 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:74 A:74 88.0 0.391 B -120.0 143.8 88.0 0.391 0.0
ARG B:74 B:74 104.0 0.462 B -132.0 138.0 104.0 0.462 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:74 A:74 110.0 0.489 B -140.3 131.3 110.0 0.489 0.0
ARG B:74 B:74 85.0 0.378 B -131.1 133.4 NA NA NA
ARG C:74 C:74 46.0 NA B -128.0 129.4 NA NA NA
ARG D:74 D:74 92.0 0.409 B -136.5 147.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ARG A:98 A:98 94.0 0.418 B -134.5 131.5