Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55211096 . C A CCDS5514.1:NM_005228.3:c.339taC>taA_NP_005219.2:p.113Y>* Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
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label_seq_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 TYR A:113 A:89 21.0 0.091 B -95.0 122.7 8.0 0.035 0.056 B:P01133:0.057
TYR C:113 B:89 23.0 0.1 B -93.6 128.3 12.0 0.052 0.048 D:P01133:0.048
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 TYR A:113 A:89 20.0 0.087 B -83.0 130.2 4.0 0.017 0.07 C:P01133:0.07
TYR B:113 B:89 22.0 0.096 B -99.1 130.5 7.0 0.03 0.066 D:P01133:0.065
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 TYR A:113 A:89 27.0 0.117 B -70.7 143.8 15.0 0.065 0.052 B:P01135:0.052
TYR C:113 B:89 25.0 0.109 B -106.3 134.3 15.0 0.065 0.044 D:P01135:0.043
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 TYR A:113 A:89 20.0 0.087 B -75.1 136.1 1.0 0.004 0.083 B:P01135:0.083
TYR C:113 B:89 19.0 0.083 B -97.3 127.0 2.0 0.009 0.074 D:P01135:0.074
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 TYR A:113 A:89 24.0 0.104 B -85.9 134.6 7.0 0.03 0.074 B:P01133:0.074
TYR C:113 B:89 32.0 0.139 B -92.8 140.8 12.0 0.052 0.087 D:P01133:0.087
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 TYR A:113 A:89 27.0 0.117 B -82.7 126.0 4.0 0.017 0.1 B:P01133:0.1
TYR C:113 B:89 38.0 0.165 B -82.5 132.6 13.0 0.057 0.108 D:P01133:0.109
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 TYR A:113 A:89 21.0 0.091 S -67.6 -72.2 21.0 0.091 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 TYR A:113 A:89 14.0 0.061 B -104.0 129.9 14.0 0.061 0.0 HOH
 6.333
 OH
 O
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 TYR A:89 A:89 13.0 0.057 B -106.6 145.5 5.0 0.022 0.035 C:P01133:0.035
 NAG
HOH
 8.059
3.635
 O
CE2
 N2
O
TYR B:89 B:89 5.0 0.022 S -107.7 133.1 1.0 0.004 0.018 D:P01133:0.017
 NAG
 7.635
 O
 O7
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 TYR A:89 A:89 22.0 0.096 B -95.5 136.2 22.0 0.096 0.0 HOH
 9.082
 N
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 TYR C:89 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 TYR A:89 A:89 75.0 0.326 S -67.6 -64.6 75.0 0.326 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 TYR A:89 A:89 22.0 0.096 B -91.8 132.5 7.0 0.03 0.066 B:P01133:0.065
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 TYR A:89 A:89 47.0 0.204 S -76.6 -58.0 47.0 0.204 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 TYR A:89 A:89 18.0 0.078 S -70.1 -58.7 18.0 0.078 0.0 HOH
 4.178
 CE2
 O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 TYR A:89 A:89 18.0 0.078 S -102.2 -60.0 18.0 0.078 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 TYR A:89 A:89 14.0 0.061 B -100.2 117.5 7.0 0.03 0.031 C:Q6QBS2:0.03
 NAG
HOH
 8.252
8.213
 O
OH
 C6
O
TYR B:89 B:89 9.0 0.039 B -89.0 123.5 6.0 0.026 0.013 D:Q6QBS2:0.013
 NAG
HOH
 8.257
8.336
 O
N
 C4
O
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 TYR A:88 A:89 21.0 0.091 S -58.9 -58.9 21.0 0.091 0.0
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 TYR A:89 A:89 13.0 0.057 B -85.7 118.0 8.0 0.035 0.022 E:O14944:0.022
 MAN
HOH
 8.155
4.339
 C
CE2
 O4
O
TYR B:89 B:89 18.0 0.078 B -88.8 122.4 NA NA NA
TYR C:89 C:89 18.0 0.078 G -83.9 116.3 NA NA NA
TYR D:89 D:89 12.0 0.052 S -95.3 105.8 6.0 0.026 0.026 H:O14944:0.026
 MAN
NAG
 8.624
9.898
 C
O
 C6
C1
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 TYR A:89 A:89 16.0 0.07 B -109.6 122.8 11.0 0.048 0.022 C:Q6UW88:0.022
 HOH
 7.557
 OH
 O
TYR D:89 D:89 30.0 0.13 S -102.5 -78.7 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 TYR A:89 A:89 17.0 0.074 B -120.4 127.3 5.0 0.022 0.052 C:P01135:0.052
 BMA
MAN
HOH
 8.478
6.711
5.733
 C
C
N
 O3
O2
O
TYR B:89 B:89 10.0 0.043 B -112.6 124.5 5.0 0.022 0.021 D:P01135:0.022
 HOH
 5.567
 N
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 TYR A:89 A:89 15.0 0.065 B -81.9 124.1 5.0 0.022 0.043 C:O14944:0.043
 NAG
MAN
 9.792
7.908
 O
C
 C8
O4
TYR B:89 B:89 18.0 0.078 B -77.8 122.9 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 TYR A:89 A:89 14.0 0.061 B -102.7 125.8 5.0 0.022 0.039 C:O14944:0.039
 MAN
 6.677
 C
 O6
TYR B:89 B:89 13.0 0.057 B -85.6 126.3 4.0 0.017 0.04 D:O14944:0.039
 NAG
BMA
MAN
 7.877
8.815
6.408
 O
C
C
 N2
O3
C6
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 TYR A:89 A:89 60.0 0.261 B -95.7 132.3 31.0 0.135 0.126 E:O14944:0.126
 MAN
 8.056
 C
 O4
TYR B:89 B:89 16.0 0.07 B -92.8 132.7 NA NA NA
TYR C:89 C:89 45.0 0.196 S -72.0 133.2 NA NA NA
TYR D:89 D:89 17.0 0.074 B -111.2 128.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 TYR A:113 A:113 16.0 0.07 B -74.9 138.4