Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 55220326 | . | G | A | CCDS5514.1:NM_005228.3:c.716gGc>gAc_NP_005219.2:p.239G>D | Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7syd | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLY | A:239 | A:215 | 3.0 | 0.04 | -156.3 | -152.9 | 3.0 | 0.04 | 0.0 | |||||||
GLY | C:239 | B:215 | 4.0 | 0.053 | -156.9 | -154.6 | 4.0 | 0.053 | 0.0 | ||||||||||||||
7sye | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLY | A:239 | A:215 | 2.0 | 0.027 | 81.6 | 167.4 | 2.0 | 0.027 | 0.0 | |||||||
GLY | B:239 | B:215 | 6.0 | 0.08 | -169.4 | 168.8 | 6.0 | 0.08 | 0.0 | ||||||||||||||
7sz5 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | GLY | A:239 | A:215 | 7.0 | 0.093 | -155.5 | -146.9 | 7.0 | 0.093 | 0.0 | |||||||
GLY | C:239 | B:215 | 9.0 | 0.12 | -160.8 | -157.0 | 9.0 | 0.12 | 0.0 | ||||||||||||||
7sz7 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-15 | GLY | A:239 | A:215 | 5.0 | 0.067 | 137.5 | 130.1 | 5.0 | 0.067 | 0.0 | |||||||
GLY | C:239 | B:215 | 3.0 | 0.04 | -158.3 | -150.6 | 3.0 | 0.04 | 0.0 | ||||||||||||||
7sz0 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | GLY | A:239 | A:215 | 4.0 | 0.053 | -155.7 | -168.1 | 4.0 | 0.053 | 0.0 | |||||||
GLY | C:239 | B:215 | 3.0 | 0.04 | -156.7 | -149.4 | 3.0 | 0.04 | 0.0 | ||||||||||||||
7sz1 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | GLY | A:239 | A:215 | 4.0 | 0.053 | 61.8 | -176.5 | 4.0 | 0.053 | 0.0 | |||||||
GLY | C:239 | B:215 | 5.0 | 0.067 | 83.1 | 167.0 | 5.0 | 0.067 | 0.0 | ||||||||||||||
5xwd | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2018-02-28 | GLY | A:239 | A:215 | 2.0 | 0.027 | -157.9 | -161.3 | 2.0 | 0.027 | 0.0 | |||||||
3qwq | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | GLY | A:239 | A:215 | 1.0 | 0.013 | E | -176.1 | -168.3 | 1.0 | 0.013 | 0.0 | ||||||
1ivo | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | GLY | A:215 | A:215 | 2.0 | 0.027 | -145.1 | -145.4 | 2.0 | 0.027 | 0.0 |
HOH |
8.457 |
N |
O |
|||
GLY | B:215 | B:215 | 3.0 | 0.04 | E | -170.0 | -166.5 | 3.0 | 0.04 | 0.0 |
HOH |
6.309 |
CA |
O |
|||||||||
4uv7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-10-14 | GLY | A:215 | A:215 | 1.0 | 0.013 | 163.3 | 175.4 | 1.0 | 0.013 | 0.0 |
HOH |
6.126 |
CA |
O |
|||
3b2v | 3 | P00533 | 100.0 | 0.0 |
X-RAY |
2008-02-19 | GLY | C:215 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
4kro | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2013-08-28 | GLY | A:215 | A:215 | 41.0 | 0.547 | 62.9 | -170.3 | 41.0 | 0.547 | 0.0 | |||||||
1nql | 1 | 4885199 | 99.84 | 0.0 |
X-RAY |
2003-03-11 | GLY | A:215 | A:215 | 2.0 | 0.027 | 137.6 | 173.6 | 2.0 | 0.027 | 0.0 | |||||||
4krp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2013-08-28 | GLY | A:215 | A:215 | 31.0 | 0.413 | -132.5 | -167.7 | 31.0 | 0.413 | 0.0 | |||||||
1yy9 | 1 | P00533 | 99.51 | 0.0 |
X-RAY |
2005-04-26 | GLY | A:215 | A:215 | 0.0 | 0.0 | 155.2 | -163.2 | 0.0 | 0.0 | 0.0 | |||||||
6aru | 1 | P00533 | 99.68 | 0.0 |
X-RAY |
2018-08-29 | GLY | A:215 | A:215 | 1.0 | 0.013 | E | -177.7 | -168.8 | 1.0 | 0.013 | 0.0 | ||||||
3njp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2010-10-13 | GLY | A:215 | A:215 | 1.0 | 0.013 | 130.1 | -162.8 | 1.0 | 0.013 | 0.0 | |||||||
GLY | B:215 | B:215 | 2.0 | 0.027 | -145.7 | -163.7 | 2.0 | 0.027 | 0.0 | ||||||||||||||
4uip | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-11-25 | GLY | A:214 | A:215 | 2.0 | 0.027 | 160.0 | -174.9 | 2.0 | 0.027 | 0.0 |
HOH |
8.580 |
O |
O |
|||
5wb7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | GLY | A:215 | A:215 | 0.0 | 0.0 | 156.4 | -159.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.939 |
O |
O |
|||
GLY | B:215 | B:215 | 1.0 | 0.013 | -174.6 | -170.9 | NA | NA | NA | ||||||||||||||
GLY | C:215 | C:215 | 1.0 | 0.013 | -162.6 | -155.6 | NA | NA | NA | ||||||||||||||
GLY | D:215 | D:215 | 1.0 | 0.013 | -174.6 | -165.5 | 1.0 | 0.013 | 0.0 | ||||||||||||||
5wb8 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | GLY | A:215 | A:215 | 1.0 | 0.013 | E | 96.2 | -175.7 | 1.0 | 0.013 | 0.0 |
HOH |
8.774 |
O |
O |
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GLY | D:215 | D:215 | 1.0 | 0.013 | 165.9 | -168.6 | NA | NA | NA | ||||||||||||||
1mox | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2003-09-10 | GLY | A:215 | A:215 | 1.0 | 0.013 | E | -173.9 | -169.9 | 1.0 | 0.013 | 0.0 |
HOH |
7.210 |
N |
O |
||
GLY | B:215 | B:215 | 0.0 | 0.0 | E | -178.9 | -168.2 | 0.0 | 0.0 | 0.0 |
HOH |
9.841 |
O |
O |
|||||||||
7len | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLY | A:215 | A:215 | 1.0 | 0.013 | 159.3 | -157.8 | 1.0 | 0.013 | 0.0 | |||||||
GLY | B:215 | B:215 | 1.0 | 0.013 | 166.3 | -164.8 | NA | NA | NA | ||||||||||||||
7lfr | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLY | A:215 | A:215 | 2.0 | 0.027 | 177.9 | -144.3 | 2.0 | 0.027 | 0.0 | |||||||
GLY | B:215 | B:215 | 1.0 | 0.013 | 169.7 | -165.5 | 1.0 | 0.013 | 0.0 | ||||||||||||||
7lfs | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | GLY | A:215 | A:215 | 2.0 | 0.027 | -160.3 | -179.0 | 2.0 | 0.027 | 0.0 | |||||||
GLY | B:215 | B:215 | 4.0 | 0.053 | -175.5 | 178.2 | NA | NA | NA | ||||||||||||||
GLY | C:215 | C:215 | 2.0 | 0.027 | 172.3 | -167.4 | NA | NA | NA | ||||||||||||||
GLY | D:215 | D:215 | 3.0 | 0.04 | -178.7 | -160.8 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00533-f1 | 1 | P00533 | 100.0 | 0.0 | GLY | A:239 | A:239 | 1.0 | 0.013 | 151.3 | -166.4 |