Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55220340 . C A CCDS5514.1:NM_005228.3:c.730Cgg>Agg_NP_005219.2:p.244R>R Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:244 A:220 156.0 0.693 S -82.3 162.6 95.0 0.422 0.271 C:P00533:0.271
ARG C:244 B:220 172.0 0.764 S -79.2 -172.0 100.0 0.444 0.32 A:P00533:0.32
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:244 A:220 121.0 0.538 S -131.8 171.5 121.0 0.538 0.0
ARG B:244 B:220 146.0 0.649 S -90.3 180.0 146.0 0.649 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:244 A:220 138.0 0.613 S -174.8 146.6 135.0 0.6 0.013 C:P00533:0.013
ARG C:244 B:220 139.0 0.618 S -167.1 165.8 139.0 0.618 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ARG A:244 A:220 166.0 0.738 S -143.8 176.0 112.0 0.498 0.24 C:P00533:0.24
ARG C:244 B:220 179.0 0.796 S -95.9 -171.4 108.0 0.48 0.316 A:P00533:0.316
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:244 A:220 174.0 0.773 S -79.2 -174.5 95.0 0.422 0.351 C:P00533:0.351
ARG C:244 B:220 151.0 0.671 S -97.1 164.5 89.0 0.396 0.275 A:P00533:0.276
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:244 A:220 133.0 0.591 S -112.7 152.4 133.0 0.591 0.0
ARG C:244 B:220 154.0 0.684 S -78.3 -174.4 154.0 0.684 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ARG A:244 A:220 155.0 0.689 S -75.8 175.6 155.0 0.689 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ARG A:244 A:220 156.0 0.693 S -95.0 162.2 156.0 0.693 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ARG A:220 A:220 150.0 0.667 S -77.0 -170.4 129.0 0.573 0.094 B:P00533:0.093
 HOH
 7.804
 N
 O
ARG B:220 B:220 145.0 0.644 S -96.7 -165.7 68.0 0.302 0.342 A:P00533:0.342
 HOH
 7.986
 N
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ARG A:220 A:220 180.0 0.8 S -91.6 163.7 180.0 0.8 0.0 HOH
 5.657
 CA
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ARG C:220 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ARG A:220 A:220 48.0 NA S -171.3 -173.7 48.0 NA NA
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ARG A:220 A:220 167.0 0.742 S -83.6 178.4 167.0 0.742 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ARG A:220 A:220 44.0 NA S -78.2 179.6 44.0 NA NA
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ARG A:220 A:220 192.0 0.853 S -70.8 151.3 192.0 0.853 0.0 NAG
NAG
HOH
 7.158
6.701
5.729
 NH2
NH1
NH1
 O6
O3
O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ARG A:220 A:220 169.0 0.751 S -93.2 164.0 169.0 0.751 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ARG A:220 A:220 185.0 0.822 S -58.0 169.9 160.0 0.711 0.111 B:P00533:0.111
ARG B:220 B:220 187.0 0.831 S -70.4 168.9 120.0 0.533 0.298 A:P00533:0.298
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ARG A:219 A:220 155.0 0.689 S -62.5 160.6 155.0 0.689 0.0 HOH
 2.956
 NH2
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ARG A:220 A:220 157.0 0.698 S -79.7 171.3 157.0 0.698 0.0
ARG B:220 B:220 158.0 0.702 S -81.0 163.3 NA NA NA
ARG C:220 C:220 131.0 0.582 S -72.0 162.1 NA NA NA
ARG D:220 D:220 163.0 0.724 S -78.8 168.7 136.0 0.604 0.12 A:P00533:0.12
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ARG A:220 A:220 133.0 0.591 S -89.6 167.7 133.0 0.591 0.0 HOH
 7.356
 O
 O
ARG D:220 D:220 171.0 0.76 S -97.9 160.2 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 ARG A:220 A:220 180.0 0.8 S -96.4 -177.2 180.0 0.8 0.0
ARG B:220 B:220 150.0 0.667 S -67.8 -164.5 150.0 0.667 0.0
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:220 A:220 35.0 NA S -75.7 169.1 35.0 NA NA
ARG B:220 B:220 42.0 NA S -90.7 172.8 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:220 A:220 170.0 0.756 S -63.2 164.0 170.0 0.756 0.0
ARG B:220 B:220 41.0 NA S -115.5 170.1 41.0 NA NA
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ARG A:220 A:220 34.0 NA S -137.8 158.8 34.0 NA NA
ARG B:220 B:220 36.0 NA S -89.8 155.7 NA NA NA
ARG C:220 C:220 41.0 NA S -69.8 156.3 NA NA NA
ARG D:220 D:220 45.0 NA S -73.4 155.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ARG A:244 A:244 173.0 0.769 S -93.7 162.3