Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55220349 . G A CCDS5514.1:NM_005228.3:c.739Gac>Aac_NP_005219.2:p.247D>N Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ASP A:247 A:223 57.0 0.38 G -125.8 24.3 57.0 0.38 0.0
ASP C:247 B:223 40.0 0.267 -111.9 17.3 40.0 0.267 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ASP A:247 A:223 55.0 0.367 S -126.5 20.1 55.0 0.367 0.0
ASP B:247 B:223 30.0 0.2 T -117.6 14.9 30.0 0.2 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ASP A:247 A:223 70.0 0.467 S -127.6 25.1 70.0 0.467 0.0
ASP C:247 B:223 73.0 0.487 S 59.7 49.6 73.0 0.487 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ASP A:247 A:223 56.0 0.373 S -121.2 7.8 56.0 0.373 0.0
ASP C:247 B:223 50.0 0.333 -114.4 5.8 50.0 0.333 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ASP A:247 A:223 44.0 0.293 -113.7 3.1 44.0 0.293 0.0
ASP C:247 B:223 51.0 0.34 -134.1 10.2 51.0 0.34 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ASP A:247 A:223 35.0 0.233 G -127.5 3.6 35.0 0.233 0.0
ASP C:247 B:223 48.0 0.32 T -115.6 16.2 48.0 0.32 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ASP A:247 A:223 41.0 0.273 G -110.1 0.5 41.0 0.273 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ASP A:247 A:223 36.0 0.24 S -112.2 15.4 36.0 0.24 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ASP A:223 A:223 30.0 0.2 S -101.0 86.5 30.0 0.2 0.0 HOH
 8.976
 OD2
 O
ASP B:223 B:223 54.0 0.36 S -107.6 57.2 48.0 0.32 0.04 A:P00533:0.04
 HOH
 9.176
 OD1
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ASP A:223 A:223 30.0 0.2 T -97.6 -18.6 30.0 0.2 0.0 HOH
 8.742
 OD2
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ASP C:223 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ASP A:223 A:223 49.0 0.327 -85.0 65.6 49.0 0.327 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ASP A:223 A:223 37.0 0.247 S -107.9 8.3 37.0 0.247 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ASP A:223 A:223 74.0 0.493 S -80.6 62.7 74.0 0.493 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ASP A:223 A:223 45.0 0.3 -107.1 9.5 45.0 0.3 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ASP A:223 A:223 37.0 0.247 -109.2 16.1 37.0 0.247 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ASP A:223 A:223 40.0 0.267 -90.2 14.8 40.0 0.267 0.0
ASP B:223 B:223 42.0 0.28 -104.9 27.9 42.0 0.28 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ASP A:222 A:223 13.0 0.087 -110.8 -4.6 13.0 0.087 0.0 HOH
 4.061
 OD2
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ASP A:223 A:223 21.0 0.14 S -96.4 6.0 21.0 0.14 0.0 HOH
 7.633
 O
 O
ASP B:223 B:223 13.0 0.087 G -89.2 2.8 NA NA NA
ASP C:223 C:223 20.0 0.133 G -90.0 5.2 NA NA NA
ASP D:223 D:223 36.0 0.24 G -92.6 5.3 36.0 0.24 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ASP A:223 A:223 23.0 0.153 -120.6 6.6 23.0 0.153 0.0 HOH
 4.555
 N
 O
ASP D:223 D:223 40.0 0.267 S -82.4 6.5 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 ASP A:223 A:223 38.0 0.253 T -110.1 19.6 38.0 0.253 0.0
ASP B:223 B:223 38.0 0.253 -113.4 9.5 38.0 0.253 0.0 HOH
 7.707
 C
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ASP A:223 A:223 55.0 0.367 G -102.1 18.7 55.0 0.367 0.0
ASP B:223 B:223 48.0 0.32 G -105.0 10.3 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ASP A:223 A:223 24.0 0.16 G -96.8 8.8 24.0 0.16 0.0
ASP B:223 B:223 44.0 0.293 G -91.2 -0.6 44.0 0.293 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ASP A:223 A:223 55.0 0.367 T -70.0 -7.3 55.0 0.367 0.0
ASP B:223 B:223 53.0 0.353 S -95.9 13.7 NA NA NA
ASP C:223 C:223 48.0 0.32 G -82.8 -1.9 NA NA NA
ASP D:223 D:223 44.0 0.293 G -108.8 6.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ASP A:247 A:247 32.0 0.213 S -104.9 -4.2