Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 55221719 | . | C | A | CCDS5514.1:NM_005228.3:c.763Cga>Aga_NP_005219.2:p.255R>R | Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7syd | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | ARG | A:255 | A:231 | 96.0 | 0.427 | -155.2 | 103.2 | 96.0 | 0.427 | 0.0 | |||||||
ARG | C:255 | B:231 | 91.0 | 0.404 | E | -135.9 | 106.1 | 91.0 | 0.404 | 0.0 | |||||||||||||
7sye | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | ARG | A:255 | A:231 | 112.0 | 0.498 | -114.2 | 135.8 | 112.0 | 0.498 | 0.0 | |||||||
ARG | B:255 | B:231 | 91.0 | 0.404 | -150.9 | 102.5 | 91.0 | 0.404 | 0.0 | ||||||||||||||
7sz5 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-22 | ARG | A:255 | A:231 | 76.0 | 0.338 | -164.9 | 146.1 | 76.0 | 0.338 | 0.0 | |||||||
ARG | C:255 | B:231 | 107.0 | 0.476 | -164.8 | 125.5 | 107.0 | 0.476 | 0.0 | ||||||||||||||
7sz7 | 1 | P00533 | 99.92 | 0.0 |
EM |
2021-12-15 | ARG | A:255 | A:231 | 115.0 | 0.511 | -155.0 | 102.2 | 115.0 | 0.511 | 0.0 | |||||||
ARG | C:255 | B:231 | 108.0 | 0.48 | B | -148.0 | 108.3 | 108.0 | 0.48 | 0.0 | |||||||||||||
7sz0 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | ARG | A:255 | A:231 | 108.0 | 0.48 | -160.6 | 109.8 | 108.0 | 0.48 | 0.0 | |||||||
ARG | C:255 | B:231 | 113.0 | 0.502 | -156.7 | 108.8 | 113.0 | 0.502 | 0.0 | ||||||||||||||
7sz1 | 1 | P00533 | 99.83 | 0.0 |
EM |
2021-12-22 | ARG | A:255 | A:231 | 114.0 | 0.507 | -114.9 | 168.2 | 114.0 | 0.507 | 0.0 | |||||||
ARG | C:255 | B:231 | 107.0 | 0.476 | -128.5 | 109.6 | 107.0 | 0.476 | 0.0 | ||||||||||||||
5xwd | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2018-02-28 | ARG | A:255 | A:231 | 74.0 | 0.329 | E | -130.8 | 111.1 | 74.0 | 0.329 | 0.0 | ||||||
3qwq | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | ARG | A:255 | A:231 | 51.0 | 0.227 | E | -115.8 | 115.0 | 51.0 | 0.227 | 0.0 | ||||||
1ivo | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | ARG | A:231 | A:231 | 76.0 | 0.338 | E | -104.3 | 107.3 | 76.0 | 0.338 | 0.0 | ||||||
ARG | B:231 | B:231 | 93.0 | 0.413 | E | -120.4 | 102.7 | 93.0 | 0.413 | 0.0 |
HOH |
6.696 |
NH2 |
O |
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4uv7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-10-14 | ARG | A:231 | A:231 | 39.0 | 0.173 | E | -107.9 | 110.7 | 39.0 | 0.173 | 0.0 |
HOH |
4.699 |
NH2 |
O |
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3b2v | 3 | P00533 | 100.0 | 0.0 |
X-RAY |
2008-02-19 | ARG | C:231 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
4kro | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2013-08-28 | ARG | A:231 | A:231 | 101.0 | 0.449 | E | -156.0 | 146.9 | 101.0 | 0.449 | 0.0 | ||||||
1nql | 1 | 4885199 | 99.84 | 0.0 |
X-RAY |
2003-03-11 | ARG | A:231 | A:231 | 105.0 | 0.467 | E | -112.4 | 110.5 | 105.0 | 0.467 | 0.0 | ||||||
4krp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2013-08-28 | ARG | A:231 | A:231 | 27.0 | NA | B | -132.2 | 152.2 | 27.0 | NA | NA | ||||||
1yy9 | 1 | P00533 | 99.51 | 0.0 |
X-RAY |
2005-04-26 | ARG | A:231 | A:231 | 93.0 | 0.413 | E | -116.7 | 141.3 | 93.0 | 0.413 | 0.0 | ||||||
6aru | 1 | P00533 | 99.68 | 0.0 |
X-RAY |
2018-08-29 | ARG | A:231 | A:231 | 73.0 | 0.324 | E | -114.9 | 115.8 | 73.0 | 0.324 | 0.0 | ||||||
3njp | 1 | P00533 | 99.84 | 0.0 |
X-RAY |
2010-10-13 | ARG | A:231 | A:231 | 83.0 | 0.369 | E | -120.1 | 104.0 | 83.0 | 0.369 | 0.0 | ||||||
ARG | B:231 | B:231 | 126.0 | 0.56 | B | -130.4 | 105.1 | 126.0 | 0.56 | 0.0 | |||||||||||||
4uip | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2015-11-25 | ARG | A:230 | A:231 | 42.0 | 0.187 | E | -113.8 | 127.5 | 42.0 | 0.187 | 0.0 |
HOH |
4.097 |
CD |
O |
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5wb7 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | ARG | A:231 | A:231 | 100.0 | 0.444 | E | -95.5 | 115.4 | 100.0 | 0.444 | 0.0 | ||||||
ARG | B:231 | B:231 | 85.0 | 0.378 | E | -102.8 | 115.2 | NA | NA | NA | |||||||||||||
ARG | C:231 | C:231 | 67.0 | 0.298 | E | -107.8 | 121.2 | NA | NA | NA | |||||||||||||
ARG | D:231 | D:231 | 89.0 | 0.396 | E | -103.5 | 114.7 | 89.0 | 0.396 | 0.0 | |||||||||||||
5wb8 | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2017-10-18 | ARG | A:231 | A:231 | 61.0 | 0.271 | E | -111.7 | 122.1 | 61.0 | 0.271 | 0.0 |
HOH |
3.187 |
NH1 |
O |
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ARG | D:231 | D:231 | 31.0 | 0.138 | E | -118.6 | 121.8 | NA | NA | NA | |||||||||||||
1mox | 1 | P00533 | 100.0 | 0.0 |
X-RAY |
2003-09-10 | ARG | A:231 | A:231 | 60.0 | 0.267 | E | -131.0 | 124.0 | 60.0 | 0.267 | 0.0 |
HOH |
4.837 |
N |
O |
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ARG | B:231 | B:231 | 63.0 | 0.28 | E | -123.8 | 113.8 | 63.0 | 0.28 | 0.0 |
HOH |
4.107 |
NE |
O |
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7len | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | ARG | A:231 | A:231 | 114.0 | 0.507 | E | -120.7 | 100.4 | 114.0 | 0.507 | 0.0 | ||||||
ARG | B:231 | B:231 | 69.0 | 0.307 | E | -121.8 | 127.9 | NA | NA | NA | |||||||||||||
7lfr | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | ARG | A:231 | A:231 | 82.0 | 0.364 | E | -125.4 | 136.2 | 82.0 | 0.364 | 0.0 | ||||||
ARG | B:231 | B:231 | 63.0 | 0.28 | E | -119.5 | 100.8 | 63.0 | 0.28 | 0.0 | |||||||||||||
7lfs | 1 | P00533 | 99.8 | 0.0 |
X-RAY |
2021-11-17 | ARG | A:231 | A:231 | 87.0 | 0.387 | E | -134.0 | 128.1 | 87.0 | 0.387 | 0.0 | ||||||
ARG | B:231 | B:231 | 81.0 | 0.36 | E | -123.8 | 121.2 | NA | NA | NA | |||||||||||||
ARG | C:231 | C:231 | 73.0 | 0.324 | E | -130.5 | 118.0 | NA | NA | NA | |||||||||||||
ARG | D:231 | D:231 | 25.0 | NA | E | -118.0 | 105.0 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p00533-f1 | 1 | P00533 | 100.0 | 0.0 | ARG | A:255 | A:255 | 55.0 | 0.244 | E | -97.3 | 107.2 |