Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55221725 . G A CCDS5514.1:NM_005228.3:c.769Gaa>Aaa_NP_005219.2:p.257E>K Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:257 A:233 160.0 0.842 S 71.3 -19.9 160.0 0.842 0.0
GLU C:257 B:233 117.0 0.616 S -48.5 -58.1 117.0 0.616 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:257 A:233 131.0 0.689 T 65.8 -21.9 131.0 0.689 0.0
GLU B:257 B:233 91.0 0.479 S 63.3 -10.1 91.0 0.479 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:257 A:233 157.0 0.826 S 54.1 60.5 157.0 0.826 0.0
GLU C:257 B:233 152.0 0.8 S 59.6 67.0 152.0 0.8 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 GLU A:257 A:233 107.0 0.563 S 55.1 70.7 107.0 0.563 0.0
GLU C:257 B:233 105.0 0.553 S 54.0 64.9 105.0 0.553 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 GLU A:257 A:233 106.0 0.558 S 69.1 -14.4 106.0 0.558 0.0
GLU C:257 B:233 67.0 0.353 S 68.3 -13.1 67.0 0.353 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 GLU A:257 A:233 140.0 0.737 S 55.7 18.5 140.0 0.737 0.0
GLU C:257 B:233 115.0 0.605 S 64.5 -9.6 115.0 0.605 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 GLU A:257 A:233 149.0 0.784 T 51.0 -109.4 149.0 0.784 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 GLU A:257 A:233 122.0 0.642 T 55.7 -99.3 122.0 0.642 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 GLU A:233 A:233 144.0 0.758 T 56.4 -128.5 144.0 0.758 0.0
GLU B:233 B:233 149.0 0.784 T 55.6 -115.6 149.0 0.784 0.0 HOH
 9.747
 O
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 GLU A:233 A:233 113.0 0.595 T 61.3 -114.8 113.0 0.595 0.0 HOH
 5.325
 OE2
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 GLU C:233 NA:NA DO NA DO DO DO NA NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 GLU A:233 A:233 91.0 NA T 56.3 63.7 91.0 NA NA
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 GLU A:233 A:233 142.0 0.747 T 62.2 -118.6 142.0 0.747 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 GLU A:233 A:233 94.0 NA T 60.9 82.6 94.0 NA NA
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 GLU A:233 A:233 130.0 0.684 S 52.0 55.9 130.0 0.684 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 GLU A:233 A:233 157.0 0.826 T 56.5 -98.4 157.0 0.826 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 GLU A:233 A:233 122.0 0.642 T 53.7 -110.6 122.0 0.642 0.0
GLU B:233 B:233 129.0 0.679 T 57.9 -111.1 129.0 0.679 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 GLU A:232 A:233 155.0 0.816 S 55.3 67.5 155.0 0.816 0.0 HOH
 2.793
 O
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLU A:233 A:233 160.0 0.842 T 53.3 -115.0 160.0 0.842 0.0
GLU B:233 B:233 150.0 0.789 T 45.1 -114.7 NA NA NA
GLU C:233 C:233 119.0 0.626 T 52.6 -112.6 NA NA NA
GLU D:233 D:233 114.0 0.6 T 50.0 -108.1 114.0 0.6 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLU A:233 A:233 146.0 0.768 S -62.5 -51.5 146.0 0.768 0.0 HOH
 4.623
 O
 O
GLU D:233 D:233 135.0 0.711 S -129.8 -65.6 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 GLU A:233 A:233 63.0 0.332 T 47.3 -92.9 63.0 0.332 0.0
GLU B:233 B:233 80.0 0.421 T 57.6 -105.7 80.0 0.421 0.0 HOH
 6.133
 O
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:233 A:233 103.0 0.542 T 53.7 -111.6 103.0 0.542 0.0
GLU B:233 B:233 112.0 0.589 S 37.9 65.5 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:233 A:233 157.0 0.826 T 58.1 -95.5 157.0 0.826 0.0
GLU B:233 B:233 120.0 0.632 S 37.1 70.0 120.0 0.632 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:233 A:233 100.0 NA T 57.2 -125.6 100.0 NA NA
GLU B:233 B:233 170.0 0.895 T 57.1 -122.9 NA NA NA
GLU C:233 C:233 92.0 0.484 T 52.7 -121.3 NA NA NA
GLU D:233 D:233 119.0 0.626 T 53.4 -117.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 GLU A:257 A:257 123.0 0.647 T 51.3 -97.5