Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55221743 . A C CCDS5514.1:NM_005228.3:c.787Acc>Ccc_NP_005219.2:p.263T>P Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 THR A:263 A:239 92.0 0.657 S -138.3 154.1 56.0 0.4 0.257 C:P00533:0.257
THR C:263 B:239 98.0 0.7 S -139.5 150.4 66.0 0.471 0.229 A:P00533:0.229
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 THR A:263 A:239 93.0 0.664 S -131.1 154.9 70.0 0.5 0.164 B:P00533:0.164
THR B:263 B:239 92.0 0.657 S -139.3 142.5 76.0 0.543 0.114 A:P00533:0.114
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 THR A:263 A:239 94.0 0.671 S -160.6 135.0 92.0 0.657 0.014 C:P00533:0.014
THR C:263 B:239 93.0 0.664 S -157.3 134.6 82.0 0.586 0.078 A:P00533:0.079
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 THR A:263 A:239 91.0 0.65 S -136.1 138.1 53.0 0.379 0.271 C:P00533:0.271
THR C:263 B:239 94.0 0.671 S -139.9 138.0 62.0 0.443 0.228 A:P00533:0.229
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 THR A:263 A:239 91.0 0.65 S -131.3 149.0 52.0 0.371 0.279 C:P00533:0.279
THR C:263 B:239 99.0 0.707 S -152.2 140.0 64.0 0.457 0.25 A:P00533:0.25
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 THR A:263 A:239 88.0 0.629 S -155.7 135.7 68.0 0.486 0.143 C:P00533:0.143
THR C:263 B:239 97.0 0.693 S -133.1 145.2 84.0 0.6 0.093 A:P00533:0.093
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 THR A:263 A:239 89.0 0.636 S -148.7 146.7 89.0 0.636 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 THR A:263 A:239 93.0 0.664 S -155.3 171.4 93.0 0.664 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 THR A:239 A:239 98.0 0.7 S -141.9 155.3 49.0 0.35 0.35 B:P00533:0.35
 HOH
 3.040
 CG2
 O
THR B:239 B:239 90.0 0.643 S -123.6 159.7 57.0 0.407 0.236 A:P00533:0.236
 HOH
 4.289
 N
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 THR A:239 A:239 79.0 0.564 S -141.2 163.4 79.0 0.564 0.0 HOH
 9.788
 CG2
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 THR C:239 A:239 167.0 1.0 360.0 137.8 167.0 1.0 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 THR A:239 A:239 101.0 0.721 S -156.7 151.3 101.0 0.721 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 THR A:239 A:239 103.0 0.736 S -142.3 144.7 103.0 0.736 0.0 NAG
 6.842
 O
 O4
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 THR A:239 A:239 103.0 0.736 S -154.8 149.6 103.0 0.736 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 THR A:239 A:239 68.0 0.486 S -156.0 152.7 68.0 0.486 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 THR A:239 A:239 96.0 0.686 S -155.4 142.4 96.0 0.686 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 THR A:239 A:239 97.0 0.693 S -148.5 125.6 64.0 0.457 0.236 B:P00533:0.236
THR B:239 B:239 100.0 0.714 S -140.8 130.3 68.0 0.486 0.228 A:P00533:0.229
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 THR A:238 A:239 101.0 0.721 S -143.6 156.0 101.0 0.721 0.0 HOH
 5.576
 OG1
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 THR A:239 A:239 96.0 0.686 S -134.2 148.8 68.0 0.486 0.2 D:P00533:0.2
THR B:239 B:239 88.0 0.629 S -141.9 153.1 NA NA NA
THR C:239 C:239 93.0 0.664 S -162.8 151.9 NA NA NA
THR D:239 D:239 96.0 0.686 S -146.2 154.9 78.0 0.557 0.129 A:P00533:0.129
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 THR A:239 A:239 83.0 0.593 S -159.8 155.1 83.0 0.593 0.0 HOH
 3.665
 CB
 O
THR D:239 D:239 89.0 0.636 S -139.4 147.7 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 THR A:239 A:239 85.0 0.607 S -161.5 148.2 65.0 0.464 0.143 B:P00533:0.143
 CD
HOH
 9.072
4.087
 CG2
CG2
 CD
O
THR B:239 B:239 79.0 0.564 S -154.6 153.3 65.0 0.464 0.1 A:P00533:0.1
 HOH
 3.456
 CA
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 THR A:239 A:239 90.0 0.643 S -148.7 151.0 90.0 0.643 0.0
THR B:239 B:239 92.0 0.657 S -143.3 156.0 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 THR A:239 A:239 89.0 0.636 S -124.4 147.2 42.0 0.3 0.336 B:P00533:0.336
THR B:239 B:239 96.0 0.686 S -133.7 145.2 54.0 0.386 0.3 A:P00533:0.3
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 THR A:239 A:239 81.0 0.579 S -145.7 153.5 81.0 0.579 0.0
THR B:239 B:239 88.0 0.629 S -137.3 145.2 NA NA NA
THR C:239 C:239 102.0 0.729 S -120.8 155.9 NA NA NA
THR D:239 D:239 101.0 0.721 S -95.8 147.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 THR A:263 A:263 67.0 0.479 S -136.9 159.3