Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55221800 . G A CCDS5514.1:NM_005228.3:c.844Gag>Aag_NP_005219.2:p.282E>K Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:282 A:258 136.0 0.716 T -118.6 39.9 136.0 0.716 0.0
GLU C:282 B:258 125.0 0.658 T -124.9 47.2 125.0 0.658 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:282 A:258 122.0 0.642 T -106.9 19.7 122.0 0.642 0.0
GLU B:282 B:258 124.0 0.653 T -105.3 -4.7 124.0 0.653 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 GLU A:282 A:258 120.0 0.632 T -119.6 20.3 120.0 0.632 0.0
GLU C:282 B:258 103.0 0.542 S -102.6 82.0 103.0 0.542 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 GLU A:282 A:258 142.0 0.747 S -129.6 86.1 142.0 0.747 0.0
GLU C:282 B:258 131.0 0.689 T -120.1 22.3 131.0 0.689 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 GLU A:282 A:258 138.0 0.726 T -109.2 32.7 138.0 0.726 0.0
GLU C:282 B:258 140.0 0.737 T -130.0 33.2 140.0 0.737 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 GLU A:282 A:258 140.0 0.737 T -134.5 22.8 140.0 0.737 0.0
GLU C:282 B:258 104.0 0.547 S -94.4 65.2 104.0 0.547 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 GLU A:282 A:258 124.0 0.653 T -80.3 -5.7 124.0 0.653 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 GLU A:282 A:258 129.0 0.679 T -100.2 20.0 129.0 0.679 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 GLU A:258 A:258 154.0 0.811 T -86.8 25.3 154.0 0.811 0.0
GLU B:258 B:258 168.0 0.884 S -125.9 43.9 168.0 0.884 0.0 HOH
 8.557
 N
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 GLU A:258 A:258 128.0 0.674 T -100.4 1.8 128.0 0.674 0.0 HOH
 8.916
 O
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 GLU C:258 A:258 74.0 NA S 99.5 -124.5 74.0 NA NA
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 GLU A:258 A:258 85.0 NA T -91.6 42.4 85.0 NA NA
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 GLU A:258 A:258 129.0 0.679 T -87.3 8.0 129.0 0.679 0.0 NAG
 3.065
 O
 O6
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 GLU A:258 A:258 71.0 NA T -105.3 5.5 71.0 NA NA
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 GLU A:258 A:258 73.0 NA T -68.9 6.3 73.0 NA NA
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 GLU A:258 A:258 145.0 0.763 T -99.3 21.3 145.0 0.763 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 GLU A:258 A:258 135.0 0.711 T -66.1 1.3 135.0 0.711 0.0
GLU B:258 B:258 140.0 0.737 T -71.2 6.2 140.0 0.737 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 GLU A:257 A:258 136.0 0.716 T -91.0 11.0 136.0 0.716 0.0 HOH
 8.457
 O
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLU A:258 A:258 63.0 NA T -75.0 -6.9 63.0 NA NA
GLU B:258 B:258 52.0 NA T -75.9 -3.4 NA NA NA
GLU C:258 C:258 152.0 0.8 T 78.3 9.7 NA NA NA
GLU D:258 D:258 150.0 0.789 T 86.9 12.2 150.0 0.789 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLU A:258 A:258 128.0 0.674 T -110.2 27.6 128.0 0.674 0.0 HOH
 4.603
 O
 O
GLU D:258 D:258 154.0 0.811 T -95.4 17.7 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 GLU A:258 A:258 153.0 0.805 T -98.7 26.1 153.0 0.805 0.0
GLU B:258 B:258 131.0 0.689 T -100.1 7.1 131.0 0.689 0.0 HOH
 7.527
 O
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:258 A:258 58.0 NA T -84.9 19.1 58.0 NA NA
GLU B:258 B:258 109.0 0.574 S -86.0 0.1 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:258 A:258 51.0 NA T -77.4 6.3 51.0 NA NA
GLU B:258 B:258 114.0 0.6 T -74.5 -3.3 114.0 0.6 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLU A:258 A:258 72.0 NA T -91.8 -4.5 72.0 NA NA
GLU B:258 B:258 56.0 NA T -85.6 3.1 NA NA NA
GLU C:258 C:258 172.0 0.905 T 56.3 47.0 NA NA NA
GLU D:258 D:258 160.0 0.842 T 60.2 23.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 GLU A:282 A:282 117.0 0.616 T -99.0 2.4