Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55221822 . C A CCDS5514.1:NM_005228.3:c.866gCc>gAc_NP_005219.2:p.289A>D Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ALA A:289 A:265 63.0 0.548 T -93.8 27.2 52.0 0.452 0.096 C:P00533:0.096
ALA C:289 B:265 61.0 0.53 T -107.3 31.8 48.0 0.417 0.113 A:P00533:0.113
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ALA A:289 A:265 63.0 0.548 S -85.5 53.5 43.0 0.374 0.174 B:P00533:0.174
ALA B:289 B:265 62.0 0.539 T -116.8 26.7 46.0 0.4 0.139 A:P00533:0.139
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ALA A:289 A:265 57.0 0.496 S 62.8 29.2 39.0 0.339 0.157 C:P00533:0.157
ALA C:289 B:265 56.0 0.487 S 61.3 36.4 38.0 0.33 0.157 A:P00533:0.157
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ALA A:289 A:265 64.0 0.557 S -141.3 27.7 59.0 0.513 0.044 C:P00533:0.043
ALA C:289 B:265 61.0 0.53 T -140.6 9.7 49.0 0.426 0.104 A:P00533:0.104
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ALA A:289 A:265 61.0 0.53 S -112.6 33.2 50.0 0.435 0.095 C:P00533:0.096
ALA C:289 B:265 56.0 0.487 T -113.8 24.9 45.0 0.391 0.096 A:P00533:0.096
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ALA A:289 A:265 53.0 0.461 S -149.3 89.2 44.0 0.383 0.078 C:P00533:0.078
ALA C:289 B:265 67.0 0.583 S 70.5 22.8 48.0 0.417 0.166 A:P00533:0.165
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ALA A:289 A:265 13.0 0.113 T -116.5 18.0 13.0 0.113 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ALA A:289 A:265 21.0 0.183 T -111.5 36.3 21.0 0.183 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ALA A:265 A:265 53.0 0.461 T -112.4 -11.5 42.0 0.365 0.096 B:P00533:0.096
 HOH
 8.357
 N
 O
ALA B:265 B:265 48.0 0.417 T -101.0 4.3 36.0 0.313 0.104 A:P00533:0.104
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ALA A:265 A:265 19.0 0.165 T -95.8 37.8 19.0 0.165 0.0 HOH
 2.880
 N
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ALA C:265 A:265 101.0 0.878 S 58.5 38.1 101.0 0.878 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ALA A:265 A:265 61.0 0.53 T -85.6 -9.3 61.0 0.53 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ALA A:265 A:265 20.0 0.174 T -92.0 26.4 20.0 0.174 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ALA A:265 A:265 60.0 0.522 T -88.2 41.2 60.0 0.522 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ALA A:265 A:265 22.0 0.191 T -96.5 38.5 22.0 0.191 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ALA A:265 A:265 17.0 0.148 T -99.6 12.2 17.0 0.148 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ALA A:265 A:265 57.0 0.496 T -111.3 18.2 44.0 0.383 0.113 B:P00533:0.113
ALA B:265 B:265 52.0 0.452 T -109.4 20.0 37.0 0.322 0.13 A:P00533:0.13
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ALA A:264 A:265 23.0 0.2 T -115.2 25.2 23.0 0.2 0.0 HOH
 5.275
 N
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ALA A:265 A:265 54.0 0.47 T -91.3 31.3 41.0 0.357 0.113 D:P00533:0.113
ALA B:265 B:265 58.0 0.504 T -98.0 32.4 NA NA NA
ALA C:265 C:265 22.0 0.191 T -102.8 38.2 NA NA NA
ALA D:265 D:265 15.0 0.13 T -101.8 39.4 15.0 0.13 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 ALA A:265 A:265 15.0 0.13 T -117.8 19.3 15.0 0.13 0.0 HOH
 5.468
 CB
 O
ALA D:265 D:265 18.0 0.157 T -102.3 24.1 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 ALA A:265 A:265 50.0 0.435 T -97.7 28.8 39.0 0.339 0.096 B:P00533:0.096
 HOH
 6.582
 O
 O
ALA B:265 B:265 61.0 0.53 T -117.3 27.3 49.0 0.426 0.104 A:P00533:0.104
 HOH
 6.248
 O
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ALA A:265 A:265 44.0 0.383 T -101.8 27.2 44.0 0.383 0.0
ALA B:265 B:265 44.0 0.383 T -102.4 19.7 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 ALA A:265 A:265 51.0 0.443 T -95.9 13.6 40.0 0.348 0.095 B:P00533:0.096
ALA B:265 B:265 46.0 0.4 T -96.4 9.3 36.0 0.313 0.087 A:P00533:0.087
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 VAL A:265 A:265 64.0 0.413 T -80.2 -14.1 64.0 0.413 0.0
VAL B:265 B:265 70.0 0.452 T -87.3 -11.0 NA NA NA
VAL C:265 C:265 31.0 0.2 T -117.6 31.3 NA NA NA
VAL D:265 D:265 62.0 0.4 T -105.1 22.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ALA A:289 A:289 17.0 0.148 T -78.3 28.6