Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55223610 . G A CCDS5514.1:NM_005228.3:c.977tGt>tAt_NP_005219.2:p.326C>Y Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 CYS A:326 A:302 28.0 0.207 E -149.0 127.5 28.0 0.207 0.0
CYS C:326 B:302 32.0 0.237 E -111.9 126.6 32.0 0.237 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 CYS A:326 A:302 8.0 0.059 E -138.5 125.4 8.0 0.059 0.0
CYS B:326 B:302 26.0 0.193 E -129.0 116.2 26.0 0.193 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 CYS A:326 A:302 22.0 0.163 -132.2 89.6 22.0 0.163 0.0
CYS C:326 B:302 26.0 0.193 E -160.4 126.3 26.0 0.193 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 CYS A:326 A:302 30.0 0.222 E -155.6 134.4 30.0 0.222 0.0
CYS C:326 B:302 27.0 0.2 E -148.3 133.3 27.0 0.2 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 CYS A:326 A:302 21.0 0.156 E -151.3 128.3 21.0 0.156 0.0
CYS C:326 B:302 18.0 0.133 E -139.7 133.2 18.0 0.133 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 CYS A:326 A:302 19.0 0.141 E -134.4 123.8 19.0 0.141 0.0
CYS C:326 B:302 25.0 0.185 -135.0 119.3 25.0 0.185 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 CYS A:326 A:302 2.0 0.015 E -81.8 142.0 2.0 0.015 0.0 ZN
ZN
ZN
 5.839
9.160
7.752
 CB
O
CB
 ZN
ZN
ZN
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 CYS A:326 A:302 21.0 0.156 E -95.9 129.8 21.0 0.156 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 CYS A:302 A:302 34.0 0.252 -159.6 161.6 34.0 0.252 0.0
CYS B:302 B:302 18.0 0.133 -173.8 108.8 18.0 0.133 0.0 HOH
 6.738
 SG
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 CYS A:302 A:302 17.0 0.126 E -91.6 126.0 17.0 0.126 0.0 HOH
 3.458
 O
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 CYS C:302 A:302 7.0 0.052 E -160.1 87.8 7.0 0.052 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 CYS A:302 A:302 12.0 0.089 E -117.5 97.9 12.0 0.089 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 CYS A:302 A:302 6.0 0.044 -99.4 128.2 6.0 0.044 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 CYS A:302 A:302 7.0 0.052 E -119.6 92.8 7.0 0.052 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 CYS A:302 A:302 7.0 0.052 E -90.8 123.4 7.0 0.052 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 CYS A:302 A:302 5.0 0.037 E -95.6 130.1 5.0 0.037 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 CYS A:302 A:302 23.0 0.17 E -114.0 128.5 22.0 0.163 0.007 B:P00533:0.007
CYS B:302 B:302 28.0 0.207 E -122.1 105.2 26.0 0.193 0.014 A:P00533:0.015
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 CYS A:301 A:302 14.0 0.104 E -113.1 125.0 14.0 0.104 0.0 HOH
 7.290
 SG
 O
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 CYS A:302 A:302 16.0 0.119 E -116.1 118.3 16.0 0.119 0.0 HOH
 8.415
 SG
 O
CYS B:302 B:302 26.0 0.193 E -129.2 137.6 NA NA NA
CYS C:302 C:302 2.0 0.015 57.7 62.7 NA NA NA
CYS D:302 D:302 4.0 0.03 61.3 49.5 4.0 0.03 0.0 HOH
 6.339
 C
 O
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 CYS A:302 A:302 18.0 0.133 E -94.9 105.6 18.0 0.133 0.0 HOH
 4.030
 SG
 O
CYS D:302 D:302 6.0 0.044 E -92.5 128.2 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 CYS A:302 A:302 16.0 0.119 -78.3 172.9 16.0 0.119 0.0 PT
PT
 8.031
9.294
 O
CB
 PT
PT
CYS B:302 B:302 46.0 0.341 E -90.8 159.9 46.0 0.341 0.0 PT
HOH
 9.717
8.036
 CB
C
 PT
O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 CYS A:302 A:302 17.0 0.126 E -87.0 145.4 17.0 0.126 0.0
CYS B:302 B:302 19.0 0.141 E -93.9 122.3 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 CYS A:302 A:302 26.0 0.193 E -78.3 138.3 26.0 0.193 0.0
CYS B:302 B:302 12.0 0.089 E -76.9 136.0 12.0 0.089 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 CYS A:302 A:302 49.0 0.363 E -98.6 101.6 49.0 0.363 0.0
CYS B:302 B:302 33.0 0.244 E -122.2 124.4 NA NA NA
CYS C:302 C:302 8.0 0.059 50.4 53.3 NA NA NA
CYS D:302 D:302 13.0 0.096 54.4 51.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 CYS A:326 A:326 7.0 0.052 E -95.5 117.4