Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55225431 . G A CCDS5514.1:NM_005228.3:c.1283gGc>gAc_NP_005219.2:p.428G>D Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 GLY A:428 A:404 0.0 0.0 60.2 40.4 0.0 0.0 0.0
GLY C:428 B:404 0.0 0.0 64.9 41.3 0.0 0.0 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 GLY A:428 A:404 1.0 0.013 102.7 37.4 1.0 0.013 0.0
GLY B:428 B:404 0.0 0.0 68.9 50.3 0.0 0.0 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 GLY A:428 A:404 0.0 0.0 63.0 48.6 0.0 0.0 0.0
GLY C:428 B:404 3.0 0.04 90.5 55.8 3.0 0.04 0.0
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 GLY A:428 A:404 0.0 0.0 90.0 53.0 0.0 0.0 0.0
GLY C:428 B:404 0.0 0.0 65.5 43.9 0.0 0.0 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 GLY A:428 A:404 0.0 0.0 64.6 42.4 0.0 0.0 0.0
GLY C:428 B:404 0.0 0.0 61.5 39.7 0.0 0.0 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 GLY A:428 A:404 1.0 0.013 101.1 43.5 1.0 0.013 0.0
GLY C:428 B:404 0.0 0.0 96.0 46.1 0.0 0.0 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 GLY A:428 A:404 0.0 0.0 78.4 34.5 0.0 0.0 0.0
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 GLY A:428 A:404 0.0 0.0 59.0 34.7 0.0 0.0 0.0
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 GLY A:404 A:404 0.0 0.0 58.9 55.8 0.0 0.0 0.0 HOH
 8.913
 C
 O
GLY B:404 B:404 1.0 0.013 67.1 35.7 1.0 0.013 0.0 HOH
 6.429
 O
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 GLY A:404 A:404 2.0 0.027 64.1 43.0 2.0 0.027 0.0 HOH
 2.717
 O
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 GLY C:404 A:404 9.0 0.12 S -27.4 -73.1 9.0 0.12 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 GLY A:404 A:404 0.0 0.0 58.6 37.2 0.0 0.0 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 GLY A:404 A:404 3.0 0.04 67.5 12.8 3.0 0.04 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 GLY A:404 A:404 0.0 0.0 58.0 43.4 0.0 0.0 0.0
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 GLY A:404 A:404 0.0 0.0 66.0 35.1 0.0 0.0 0.0 HOH
 6.035
 O
 O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 GLY A:404 A:404 0.0 0.0 59.7 35.5 0.0 0.0 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 GLY A:404 A:404 0.0 0.0 60.6 37.2 0.0 0.0 0.0 HOH
 9.989
 O
 O
GLY B:404 B:404 0.0 0.0 70.2 26.6 0.0 0.0 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 GLY A:403 A:404 0.0 0.0 60.2 49.8 0.0 0.0 0.0
5wb7 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLY A:404 A:404 0.0 0.0 61.8 34.0 0.0 0.0 0.0
GLY B:404 B:404 0.0 0.0 59.1 31.9 NA NA NA
GLY C:404 C:404 1.0 0.013 68.3 24.8 NA NA NA
GLY D:404 D:404 0.0 0.0 72.3 11.7 0.0 0.0 0.0
5wb8 1 P00533 100.0 0.0 X-RAY
 2017-10-18 GLY A:404 A:404 0.0 0.0 68.9 29.2 0.0 0.0 0.0 HOH
 2.837
 O
 O
GLY D:404 D:404 0.0 0.0 65.1 26.2 NA NA NA
1mox 1 P00533 100.0 0.0 X-RAY
 2003-09-10 GLY A:404 A:404 0.0 0.0 69.3 18.7 0.0 0.0 0.0
GLY B:404 B:404 0.0 0.0 75.2 33.6 0.0 0.0 0.0 HOH
 5.930
 N
 O
7len 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLY A:404 A:404 0.0 0.0 68.3 37.6 0.0 0.0 0.0
GLY B:404 B:404 0.0 0.0 61.4 32.7 NA NA NA
7lfr 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLY A:404 A:404 0.0 0.0 63.2 31.4 0.0 0.0 0.0
GLY B:404 B:404 0.0 0.0 58.7 41.9 0.0 0.0 0.0
7lfs 1 P00533 99.8 0.0 X-RAY
 2021-11-17 GLY A:404 A:404 0.0 0.0 64.8 28.0 0.0 0.0 0.0
GLY B:404 B:404 0.0 0.0 66.3 38.6 NA NA NA
GLY C:404 C:404 0.0 0.0 64.9 30.9 NA NA NA
GLY D:404 D:404 0.0 0.0 63.6 46.3 NA NA NA
3p0y 1 P00533 99.52 3e-141 X-RAY
 2011-10-26 GLY A:95 A:404 0.0 0.0 60.4 33.5 0.0 0.0 0.0 HOH
 3.652
 O
 O
3b2u 3 P00533 99.51 2e-140 X-RAY
 2008-02-19 GLY C:98 A:404 0.0 0.0 86.2 31.3 0.0 0.0 0.0 HOH
 6.117
 N
 O
GLY F:98 B:404 0.0 0.0 51.4 43.6 NA NA NA
GLY I:98 E:404 0.0 0.0 65.5 37.1 NA NA NA
GLY L:98 I:404 0.0 0.0 48.8 29.9 NA NA NA
GLY O:98 M:404 0.0 0.0 53.4 32.5 NA NA NA
GLY R:98 P:404 0.0 0.0 59.5 43.6 NA NA NA
GLY U:98 S:404 0.0 0.0 56.7 38.5 NA NA NA
GLY X:98 V:404 0.0 0.0 86.8 27.2 NA NA NA
3c09 3 P00533 99.51 2e-140 X-RAY
 2008-04-15 GLY C:98 A:404 0.0 0.0 73.8 8.1 NA NA NA
GLY F:98 D:404 0.0 0.0 75.3 20.4 0.0 0.0 0.0
4krl 2 P00533 99.51 2e-140 X-RAY
 2013-08-28 GLY B:98 A:404 0.0 0.0 56.8 39.2 0.0 0.0 0.0 HOH
 7.605
 O
 O
4krm 1 P00533 99.51 2e-140 X-RAY
 2013-08-28 GLY A:98 A:404 0.0 0.0 73.7 35.4 0.0 0.0 0.0 HOH
 9.258
 HA2
 O
GLY C:98 C:404 0.0 0.0 63.9 34.5 NA NA NA
GLY E:98 E:404 0.0 0.0 78.4 30.2 NA NA NA
GLY G:98 G:404 0.0 0.0 77.4 35.8 NA NA NA
GLY I:98 I:404 0.0 0.0 74.5 34.7 NA NA NA
GLY K:98 K:404 0.0 0.0 61.0 32.4 NA NA NA
6b3s 1 P00533 99.02 1e-139 X-RAY
 2017-12-06 GLY A:98 A:404 0.0 0.0 58.9 36.9 0.0 0.0 0.0
GLY D:98 B:404 0.0 0.0 55.0 44.0 NA NA NA
GLY G:98 E:404 0.0 0.0 60.0 33.5 NA NA NA
GLY J:98 I:404 0.0 0.0 61.9 32.3 NA NA NA
5sx4 3 P00533 98.44 5e-129 X-RAY
 2016-10-05 GLY E:98 M:404 0.0 0.0 71.3 43.6 0.0 0.0 0.0 HOH
 6.174
 O
 O
GLY F:98 N:404 0.0 0.0 71.0 28.2 NA NA NA
5sx5 3 P00533 97.92 3e-128 X-RAY
 2016-10-05 GLY E:98 M:404 0.0 0.0 67.4 36.8 0.0 0.0 0.0
GLY F:98 N:404 0.0 0.0 64.6 34.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 GLY A:428 A:428 0.0 0.0 61.6 27.8