Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55229275 . A C CCDS5514.1:NM_005228.3:c.1582Aat>Cat_NP_005219.2:p.528N>H Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ASN A:528 A:504 108.0 0.675 S -116.1 -60.5 108.0 0.675 0.0
ASN C:528 B:504 88.0 0.55 S -110.0 -78.8 88.0 0.55 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ASN A:528 A:504 83.0 0.519 S -112.5 -57.9 83.0 0.519 0.0
ASN B:528 B:504 65.0 0.406 S -94.6 -13.9 65.0 0.406 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ASN A:528 A:504 107.0 0.669 S -118.8 -55.2 107.0 0.669 0.0
ASN C:528 NA:NA DO NA DO DO DO NA NA NA
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ASN A:528 A:504 80.0 0.5 S -114.9 -58.0 80.0 0.5 0.0
ASN C:528 B:504 71.0 0.444 B 44.1 -89.6 71.0 0.444 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ASN A:528 A:504 90.0 0.562 S -114.9 -59.2 90.0 0.562 0.0
ASN C:528 B:504 88.0 0.55 S -117.8 -78.7 88.0 0.55 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ASN A:528 A:504 84.0 0.525 S -139.9 -162.8 84.0 0.525 0.0
ASN C:528 B:504 89.0 0.556 S -136.3 -57.3 89.0 0.556 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ASN A:528 A:504 89.0 0.556 S -127.7 -88.1 89.0 0.556 0.0 NAG
ZN
 1.450
9.420
 ND2
ND2
 C1
ZN
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ASN A:528 A:504 113.0 0.706 S -133.3 -113.7 113.0 0.706 0.0 NAG
NAG
FUC
 1.431
6.402
5.671
 ND2
ND2
ND2
 C1
C1
O2
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ASN A:504 A:504 128.0 0.8 S 70.1 99.4 128.0 0.8 0.0 HOH
 5.261
 ND2
 O
ASN B:504 B:504 145.0 0.906 T 62.3 51.0 145.0 0.906 0.0 HOH
 6.593
 CB
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ASN A:504 A:504 110.0 0.688 S -141.4 -85.6 110.0 0.688 0.0 NAG
NAG
HOH
 1.471
6.326
2.974
 ND2
ND2
O
 C1
C1
O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ASN C:504 A:504 107.0 0.669 S -109.1 -122.2 107.0 0.669 0.0 NAG
 1.444
 ND2
 C1
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ASN A:504 A:504 76.0 0.475 S -102.5 -78.0 76.0 0.475 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ASN A:504 A:504 66.0 0.412 S -106.4 -84.9 66.0 0.412 0.0 NAG
 1.445
 ND2
 C1
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ASN A:504 A:504 71.0 0.444 S -123.8 -72.3 71.0 0.444 0.0 NAG
 1.449
 ND2
 C1
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ASN A:504 A:504 86.0 0.537 S -117.4 -88.9 86.0 0.537 0.0 NAG
HOH
 1.449
7.270
 ND2
ND2
 C1
O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ASN A:504 A:504 58.0 0.362 S -130.9 -111.7 58.0 0.362 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ASN A:504 A:504 88.0 0.55 S -95.6 -81.6 88.0 0.55 0.0 NAG
 1.440
 ND2
 C1
ASN B:504 B:504 89.0 0.556 S -110.1 -78.7 89.0 0.556 0.0 NAG
 1.439
 ND2
 C1
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ASN A:503 A:504 87.0 0.544 S -106.6 -85.3 87.0 0.544 0.0 NAG
HOH
 1.486
8.002
 ND2
O
 C1
O
3p0y 1 P00533 99.52 3e-141 X-RAY
 2011-10-26 ASN A:195 NA:NA DO NA DO DO DO NA NA NA
3b2u 3 P00533 99.51 2e-140 X-RAY
 2008-02-19 ASN C:198 NA:NA DO NA DO DO DO NA NA NA
ASN F:198 NA:NA DO NA DO DO DO NA NA NA
ASN I:198 NA:NA DO NA DO DO DO NA NA NA
ASN L:198 NA:NA DO NA DO DO DO NA NA NA
ASN O:198 NA:NA DO NA DO DO DO NA NA NA
ASN R:198 NA:NA DO NA DO DO DO NA NA NA
ASN U:198 NA:NA DO NA DO DO DO NA NA NA
ASN X:198 NA:NA DO NA DO DO DO NA NA NA
3c09 3 P00533 99.51 2e-140 X-RAY
 2008-04-15 ASN C:198 NA:NA DO NA DO DO DO NA NA NA
ASN F:198 NA:NA DO NA DO DO DO NA NA NA
4krl 2 P00533 99.51 2e-140 X-RAY
 2013-08-28 ASN B:198 A:504 101.0 NA S -106.0 -87.3 101.0 NA NA MES
HOH
 4.983
3.372
 N
CA
 O2S
O
4krm 1 P00533 99.51 2e-140 X-RAY
 2013-08-28 ASN A:198 NA:NA DO NA DO DO DO NA NA NA
ASN C:198 NA:NA DO NA DO DO DO NA NA NA
ASN E:198 NA:NA DO NA DO DO DO NA NA NA
ASN G:198 NA:NA DO NA DO DO DO NA NA NA
ASN I:198 NA:NA DO NA DO DO DO NA NA NA
ASN K:198 NA:NA DO NA DO DO DO NA NA NA
6b3s 1 P00533 99.02 1e-139 X-RAY
 2017-12-06 ASN A:198 NA:NA DO NA DO DO DO NA NA NA
ASN D:198 NA:NA DO NA DO DO DO NA NA NA
ASN G:198 NA:NA DO NA DO DO DO NA NA NA
ASN J:198 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ASN A:528 A:528 88.0 0.55 S -116.5 -80.7