Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55229284 . C A CCDS5514.1:NM_005228.3:c.1591Cga>Aga_NP_005219.2:p.531R>R Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:531 A:507 95.0 0.422 E -129.2 86.1 95.0 0.422 0.0
ARG C:531 B:507 78.0 0.347 S -110.6 66.0 78.0 0.347 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:531 A:507 73.0 0.324 E -135.8 86.0 73.0 0.324 0.0
ARG B:531 B:507 79.0 0.351 S -110.6 66.1 79.0 0.351 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 ARG A:531 A:507 78.0 0.347 E -95.8 33.4 78.0 0.347 0.0
ARG C:531 NA:NA DO NA DO DO DO NA NA NA
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 ARG A:531 A:507 66.0 0.293 S -68.5 102.6 66.0 0.293 0.0
ARG C:531 B:507 78.0 0.347 -110.6 66.1 78.0 0.347 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:531 A:507 69.0 0.307 S -78.1 75.0 69.0 0.307 0.0
ARG C:531 B:507 78.0 0.347 S -110.6 66.1 78.0 0.347 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 ARG A:531 A:507 79.0 0.351 S -77.7 60.5 79.0 0.351 0.0
ARG C:531 B:507 80.0 0.356 S -110.6 66.1 80.0 0.356 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 ARG A:531 A:507 74.0 0.329 E -117.1 99.9 74.0 0.329 0.0 NAG
ZN
 7.574
4.487
 NH1
NH2
 O6
ZN
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 ARG A:531 A:507 79.0 0.351 E -124.4 110.8 79.0 0.351 0.0 NAG
 9.706
 NH2
 C8
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 ARG A:507 A:507 185.0 0.822 -123.2 179.1 185.0 0.822 0.0 HOH
 4.587
 N
 O
ARG B:507 B:507 176.0 0.782 -173.4 -145.0 176.0 0.782 0.0 HOH
 3.462
 O
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 ARG A:507 A:507 79.0 0.351 E -119.7 111.4 79.0 0.351 0.0 HOH
 3.088
 NH1
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 ARG C:507 A:507 77.0 0.342 E -118.4 124.0 77.0 0.342 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 ARG A:507 A:507 78.0 0.347 E -95.8 98.6 78.0 0.347 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 ARG A:507 A:507 61.0 0.271 E -114.9 93.5 61.0 0.271 0.0
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 ARG A:507 A:507 90.0 0.4 S -97.0 -77.8 90.0 0.4 0.0 NAG
 9.939
 HH22
 O7
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 ARG A:507 A:507 63.0 0.28 S -75.3 -104.8 63.0 0.28 0.0
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 ARG A:507 A:507 62.0 0.276 E -122.8 111.1 62.0 0.276 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 ARG A:507 A:507 64.0 0.284 E -99.5 84.7 64.0 0.284 0.0
ARG B:507 B:507 75.0 0.333 S -110.6 66.0 75.0 0.333 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 ARG A:506 A:507 104.0 0.462 S -92.1 -74.5 104.0 0.462 0.0
3p0y 1 P00533 99.52 3e-141 X-RAY
 2011-10-26 ARG A:198 NA:NA DO NA DO DO DO NA NA NA
3b2u 3 P00533 99.51 2e-140 X-RAY
 2008-02-19 ARG C:201 NA:NA DO NA DO DO DO NA NA NA
ARG F:201 NA:NA DO NA DO DO DO NA NA NA
ARG I:201 NA:NA DO NA DO DO DO NA NA NA
ARG L:201 NA:NA DO NA DO DO DO NA NA NA
ARG O:201 NA:NA DO NA DO DO DO NA NA NA
ARG R:201 NA:NA DO NA DO DO DO NA NA NA
ARG U:201 NA:NA DO NA DO DO DO NA NA NA
ARG X:201 NA:NA DO NA DO DO DO NA NA NA
3c09 3 P00533 99.51 2e-140 X-RAY
 2008-04-15 ARG C:201 NA:NA DO NA DO DO DO NA NA NA
ARG F:201 NA:NA DO NA DO DO DO NA NA NA
4krl 2 P00533 99.51 2e-140 X-RAY
 2013-08-28 ARG B:201 A:507 119.0 NA S -66.5 -25.1 119.0 NA NA
4krm 1 P00533 99.51 2e-140 X-RAY
 2013-08-28 ARG A:201 NA:NA DO NA DO DO DO NA NA NA
ARG C:201 NA:NA DO NA DO DO DO NA NA NA
ARG E:201 NA:NA DO NA DO DO DO NA NA NA
ARG G:201 NA:NA DO NA DO DO DO NA NA NA
ARG I:201 NA:NA DO NA DO DO DO NA NA NA
ARG K:201 NA:NA DO NA DO DO DO NA NA NA
6b3s 1 P00533 99.02 1e-139 X-RAY
 2017-12-06 ARG A:201 NA:NA DO NA DO DO DO NA NA NA
ARG D:201 NA:NA DO NA DO DO DO NA NA NA
ARG G:201 NA:NA DO NA DO DO DO NA NA NA
ARG J:201 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 ARG A:531 A:531 84.0 0.373 E -102.6 88.4