Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 55229298 . C A CCDS5514.1:NM_005228.3:c.1605tgC>tgA_NP_005219.2:p.535C>* Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7syd 1 P00533 99.92 0.0 EM
 2021-12-22 CYS A:535 A:511 10.0 0.074 E -93.8 135.1 10.0 0.074 0.0
CYS C:535 B:511 8.0 0.059 E -88.8 149.7 8.0 0.059 0.0
7sye 1 P00533 99.92 0.0 EM
 2021-12-22 CYS A:535 A:511 8.0 0.059 E -110.8 130.9 8.0 0.059 0.0
CYS B:535 B:511 8.0 0.059 E -88.9 149.8 8.0 0.059 0.0
7sz5 1 P00533 99.92 0.0 EM
 2021-12-22 CYS A:535 A:511 4.0 0.03 E -91.3 137.7 4.0 0.03 0.0
CYS C:535 NA:NA DO NA DO DO DO NA NA NA
7sz7 1 P00533 99.92 0.0 EM
 2021-12-15 CYS A:535 A:511 3.0 0.022 E -79.7 140.4 3.0 0.022 0.0
CYS C:535 B:511 3.0 0.022 -88.9 149.7 3.0 0.022 0.0
7sz0 1 P00533 99.83 0.0 EM
 2021-12-22 CYS A:535 A:511 1.0 0.007 -126.7 136.5 1.0 0.007 0.0
CYS C:535 B:511 4.0 0.03 E -88.9 149.7 4.0 0.03 0.0
7sz1 1 P00533 99.83 0.0 EM
 2021-12-22 CYS A:535 A:511 7.0 0.052 B -69.1 116.0 7.0 0.052 0.0
CYS C:535 B:511 25.0 0.185 E -88.9 149.7 25.0 0.185 0.0
5xwd 1 P00533 99.84 0.0 X-RAY
 2018-02-28 CYS A:535 A:511 5.0 0.037 E -76.4 141.1 5.0 0.037 0.0 ZN
 8.119
 O
 ZN
3qwq 1 P00533 100.0 0.0 X-RAY
 2012-02-01 CYS A:535 A:511 3.0 0.022 E -82.0 128.4 3.0 0.022 0.0 NAG
NAG
 8.362
8.388
 C
O
 C1
O7
1ivo 1 P00533 100.0 0.0 X-RAY
 2002-10-16 CYS A:511 A:511 14.0 0.104 -127.2 143.5 14.0 0.104 0.0 HOH
 3.923
 O
 O
CYS B:511 B:511 14.0 0.104 -122.9 20.1 14.0 0.104 0.0 HOH
 5.273
 O
 O
4uv7 1 P00533 100.0 0.0 X-RAY
 2015-10-14 CYS A:511 A:511 3.0 0.022 E -68.1 130.7 3.0 0.022 0.0 HOH
 2.712
 O
 O
3b2v 3 P00533 100.0 0.0 X-RAY
 2008-02-19 CYS C:511 A:511 12.0 0.089 E -35.3 150.7 12.0 0.089 0.0
4kro 1 P00533 100.0 0.0 X-RAY
 2013-08-28 CYS A:511 A:511 4.0 0.03 E -83.9 143.9 4.0 0.03 0.0
1nql 1 4885199 99.84 0.0 X-RAY
 2003-03-11 CYS A:511 A:511 4.0 0.03 E -91.1 147.5 4.0 0.03 0.0 NAG
 9.856
 C
 C1
4krp 1 P00533 99.84 0.0 X-RAY
 2013-08-28 CYS A:511 A:511 4.0 0.03 E -81.2 148.1 4.0 0.03 0.0 NAG
 8.541
 HB3
 H1
1yy9 1 P00533 99.51 0.0 X-RAY
 2005-04-26 CYS A:511 A:511 4.0 0.03 E -93.6 140.4 4.0 0.03 0.0 NAG
HOH
 7.806
7.727
 CB
CB
 O7
O
6aru 1 P00533 99.68 0.0 X-RAY
 2018-08-29 CYS A:511 A:511 5.0 0.037 E -82.4 126.9 5.0 0.037 0.0
3njp 1 P00533 99.84 0.0 X-RAY
 2010-10-13 CYS A:511 A:511 5.0 0.037 E -83.1 139.0 5.0 0.037 0.0 NAG
 9.426
 C
 C8
CYS B:511 B:511 4.0 0.03 E -88.8 149.8 4.0 0.03 0.0
4uip 1 P00533 100.0 0.0 X-RAY
 2015-11-25 CYS A:510 A:511 4.0 0.03 -102.3 -67.5 4.0 0.03 0.0 NAG
 9.544
 O
 C1
3p0y 1 P00533 99.52 3e-141 X-RAY
 2011-10-26 CYS A:202 NA:NA DO NA DO DO DO NA NA NA
3b2u 3 P00533 99.51 2e-140 X-RAY
 2008-02-19 CYS C:205 NA:NA DO NA DO DO DO NA NA NA
CYS F:205 NA:NA DO NA DO DO DO NA NA NA
CYS I:205 NA:NA DO NA DO DO DO NA NA NA
CYS L:205 NA:NA DO NA DO DO DO NA NA NA
CYS O:205 NA:NA DO NA DO DO DO NA NA NA
CYS R:205 NA:NA DO NA DO DO DO NA NA NA
CYS U:205 NA:NA DO NA DO DO DO NA NA NA
CYS X:205 NA:NA DO NA DO DO DO NA NA NA
3c09 3 P00533 99.51 2e-140 X-RAY
 2008-04-15 CYS C:205 NA:NA DO NA DO DO DO NA NA NA
CYS F:205 NA:NA DO NA DO DO DO NA NA NA
4krl 2 P00533 99.51 2e-140 X-RAY
 2013-08-28 CYS B:205 A:511 38.0 0.281 -66.1 360.0 38.0 0.281 0.0 MES
 9.363
 SG
 C8
4krm 1 P00533 99.51 2e-140 X-RAY
 2013-08-28 CYS A:205 NA:NA DO NA DO DO DO NA NA NA
CYS C:205 NA:NA DO NA DO DO DO NA NA NA
CYS E:205 NA:NA DO NA DO DO DO NA NA NA
CYS G:205 G:511 137.0 1.0 360.0 360.0 NA NA NA
CYS I:205 NA:NA DO NA DO DO DO NA NA NA
CYS K:205 NA:NA DO NA DO DO DO NA NA NA
6b3s 1 P00533 99.02 1e-139 X-RAY
 2017-12-06 CYS A:205 NA:NA DO NA DO DO DO NA NA NA
CYS D:205 NA:NA DO NA DO DO DO NA NA NA
CYS G:205 NA:NA DO NA DO DO DO NA NA NA
CYS J:205 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p00533-f1 1 P00533 100.0 0.0 CYS A:535 A:535 6.0 0.044 E -72.5 129.4