Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 73117255 . T A CCDS34655.1:NM_004603.3:c.598Agt>Tgt_NP_004594.1:p.200S>C Homo sapiens syntaxin 1A (STX1A), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3c98 2 P32851 99.63 0.0 X-RAY
 2008-03-25 SER B:212 B:200 35.0 0.304 H -62.3 -36.8 35.0 0.304 0.0 HOH
 7.593
 N
 O
6mdm 3 P32851 99.22 0.0 EM
 2018-09-19 SER H:200 I:200 33.0 0.287 H -77.8 -49.4 33.0 0.287 0.0
6mdn 3 P32851 99.22 0.0 EM
 2018-09-19 SER H:200 I:200 52.0 0.452 H -85.1 -52.2 52.0 0.452 0.0
6ip1 2 P32851 99.6 0.0 EM
 2019-04-24 SER B:201 B:200 74.0 0.643 H -68.6 -16.6 74.0 0.643 0.0
4jeh 2 P32851 99.59 5e-177 X-RAY
 2013-07-17 SER B:177 B:200 38.0 0.33 H -64.1 -35.2 38.0 0.33 0.0 HOH
 3.253
 OG
 O
4jeu 2 P32851 99.59 2e-176 X-RAY
 2013-07-17 SER B:199 B:200 46.0 0.4 H -59.7 -37.4 46.0 0.4 0.0
2m8r 1 P32851 97.17 8e-70 NMR
 2013-11-20 SER A:21 A:200 35.0 0.304 H -83.7 -26.7 35.0 0.304 0.0
3hd7 2 P32851 97.17 8e-70 X-RAY
 2009-07-14 SER B:21 B:200 55.0 0.478 H -58.1 -43.7 55.0 0.478 0.0
SER F:21 F:200 53.0 0.461 H -55.2 -45.5 NA NA NA
3ipd 2 P32851 97.17 8e-70 X-RAY
 2009-09-01 SER B:21 B:200 49.0 0.426 H -55.9 -21.5 49.0 0.426 0.0
SER F:21 F:200 49.0 0.426 H -55.1 -21.4 NA NA NA
1sfc 2 P32851 100.0 7e-53 X-RAY
 1998-10-28 SER B:21 B:200 64.0 0.557 H -56.8 -43.6 64.0 0.557 0.0
SER F:21 F:200 43.0 0.374 H -60.3 -45.5 NA NA NA
SER J:21 J:200 58.0 0.504 H -63.6 -50.9 NA NA NA
1jth 2 P32851 100.0 2e-48 X-RAY
 2001-11-28 SER B:10 B:200 65.0 0.565 H -56.8 -43.3 65.0 0.565 0.0 HOH
 6.473
 N
 O
SER D:10 D:200 71.0 0.617 H -64.6 -37.8 71.0 0.617 0.0 HOH
 3.848
 CB
 O
1hvv 1 P32851 100.0 4e-47 X-RAY
 2001-01-31 SER A:11 A:200 34.0 0.296 H -57.3 -45.6 34.0 0.296 0.0 HOH
 5.629
 O
 O
SER B:11 B:200 55.0 0.478 H -58.9 -37.2 55.0 0.478 0.0 HOH
 6.909
 O
 O
SER C:11 C:200 66.0 0.574 H -61.4 -40.4 66.0 0.574 0.0 HOH
 2.740
 OG
 O
SER D:11 D:200 52.0 0.452 H -69.5 -34.7 52.0 0.452 0.0 HOH
 7.228
 C
 O
1urq 2 P32851 98.65 9e-45 X-RAY
 2004-08-26 SER B:16 B:200 70.0 0.609 H -70.0 -39.2 70.0 0.609 0.0 HOH
 2.395
 O
 O
2n1t 2 P32851 100.0 1e-44 NMR
 2015-06-03 SER B:13 B:200 62.0 0.539 H -60.1 -44.5 62.0 0.539 0.0
1n7s 2 P32851 100.0 7e-40 X-RAY
 2002-12-27 SER B:12 B:200 50.0 0.435 H -61.9 -42.5 50.0 0.435 0.0 HOH
 2.958
 O
 O
3j96 4 P32851 100.0 7e-40 EM
 2015-01-28 SER L:11 L:200 66.0 0.574 H -54.7 -20.2 66.0 0.574 0.0
3j97 4 P32851 100.0 7e-40 EM
 2015-01-28 SER L:11 L:200 41.0 0.357 H -47.2 -30.6 41.0 0.357 0.0
3j98 4 P32851 100.0 7e-40 EM
 2015-01-28 SER L:11 L:200 63.0 0.548 H -54.4 -46.5 63.0 0.548 0.0
3j99 4 P32851 100.0 7e-40 EM
 2015-01-28 SER L:11 L:200 63.0 0.548 H -54.4 -46.5 63.0 0.548 0.0
5ccg 2 P32851 100.0 7e-40 X-RAY
 2015-08-12 SER B:11 B:200 72.0 0.626 H -63.0 -45.4 72.0 0.626 0.0
SER H:11 H:200 59.0 0.513 H -62.7 -45.4 NA NA NA
5cch 2 P32851 100.0 7e-40 X-RAY
 2015-08-12 SER B:11 B:200 69.0 0.6 H -61.2 -44.5 69.0 0.6 0.0
5cci 2 P32851 100.0 7e-40 X-RAY
 2015-08-12 SER B:11 B:200 66.0 0.574 H -61.8 -52.8 66.0 0.574 0.0
5w5c 2 P32851 100.0 7e-40 X-RAY
 2017-08-23 SER B:11 B:200 71.0 0.617 H -72.6 -22.9 24.0 0.209 0.408 F:P21707:0.409
 HOH
 2.915
 OG
 O
5w5d 2 P32851 100.0 7e-40 X-RAY
 2017-08-23 SER B:11 B:200 82.0 0.713 H -61.4 -49.5 16.0 0.139 0.574 F:P21707:0.574
 HOH
 8.285
 N
 O
6mti 4 P32851 100.0 7e-40 EM
 2019-04-24 SER H:11 B:200 68.0 0.591 H -61.9 -52.8 68.0 0.591 0.0
SER L:11 F:200 66.0 0.574 H -61.9 -52.8 66.0 0.574 0.0
SER P:11 J:200 65.0 0.565 H -61.9 -52.7 65.0 0.565 0.0
SER T:11 N:200 66.0 0.574 H -61.9 -52.8 66.0 0.574 0.0
SER X:11 R:200 68.0 0.591 H -61.8 -52.9 68.0 0.591 0.0
SER BA:11 V:200 69.0 0.6 H -61.9 -52.8 69.0 0.6 0.0
5kj7 2 P32851 100.0 8e-40 X-RAY
 2016-10-19 SER B:10 B:200 72.0 0.626 H -63.2 -44.1 72.0 0.626 0.0
SER H:10 H:200 58.0 0.504 H -63.2 -43.8 NA NA NA
5kj8 2 P32851 100.0 8e-40 X-RAY
 2016-10-19 SER B:10 B:200 67.0 0.583 H -65.8 -46.1 67.0 0.583 0.0
SER H:10 H:200 53.0 0.461 H -66.3 -45.9 NA NA NA
6wvw 2 P32851 100.0 8e-40 X-RAY
 2021-03-17 SER B:10 B:200 67.0 0.583 H -61.8 -39.1 67.0 0.583 0.0 HOH
 6.234
 H
 O
SER F:10 F:200 65.0 0.565 H -62.2 -39.7 NA NA NA
3rk2 2 P32851 100.0 9e-38 X-RAY
 2011-07-27 SER B:12 B:200 60.0 0.522 H -62.3 -40.8 60.0 0.522 0.0 HOH
 5.682
 O
 O
SER F:12 F:200 58.0 0.504 H -64.3 -39.8 NA NA NA
3rk3 2 P32851 100.0 9e-38 X-RAY
 2011-07-27 SER B:12 B:200 70.0 0.609 H -41.5 -58.7 70.0 0.609 0.0
3rl0 2 P32851 100.0 9e-38 X-RAY
 2011-07-27 SER B:12 B:200 64.0 0.557 H -60.8 -43.0 64.0 0.557 0.0
SER F:12 F:200 64.0 0.557 H -61.2 -42.3 NA NA NA
SER J:12 J:200 65.0 0.565 H -60.7 -42.9 NA NA NA
SER N:12 N:200 65.0 0.565 H -60.3 -43.3 NA NA NA
SER R:12 R:200 67.0 0.583 H -61.2 -42.3 NA NA NA
SER V:12 V:200 66.0 0.574 H -60.5 -42.9 NA NA NA
SER Z:12 Z:200 65.0 0.565 H -60.1 -43.2 NA NA NA
SER DA:12 d:200 65.0 0.565 H -60.6 -42.9 NA NA NA
1kil 2 P32851 100.0 2e-35 X-RAY
 2002-03-13 SER B:12 B:200 74.0 0.643 H -64.1 -45.5 74.0 0.643 0.0 HOH
 7.863
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q16623-f1 1 Q16623 100.0 0.0 SER A:200 A:200 53.0 0.461 H -59.6 -40.7
af-p61266-f1 1 P61266 83.33 3e-178 ASN A:199 A:199 73.0 0.456 H -62.4 -36.0