Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557323 . G A CCDS5749.1:NM_000108.3:c.960aaG>aaA_NP_000099.2:p.320K>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 LYS A:306 A:285 131.0 0.655 T -54.1 131.3 131.0 0.655 0.0 FAD
HOH
 4.617
3.162
 O
O
 N6A
O
LYS B:306 B:285 98.0 0.49 T -66.2 135.8 98.0 0.49 0.0 FAD
 4.793
 O
 N6A
LYS C:306 C:285 130.0 0.65 T -66.9 135.1 NA NA NA
LYS D:306 D:285 118.0 0.59 T -47.1 129.2 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 LYS A:285 A:285 125.0 0.625 T -48.4 128.0 125.0 0.625 0.0 FAD
HOH
 4.524
3.306
 O
N
 N6A
O
LYS B:285 B:285 115.0 0.575 T -91.9 146.9 115.0 0.575 0.0 FAD
HOH
 4.338
2.922
 O
O
 N6A
O
LYS C:285 C:285 118.0 0.59 T -46.0 142.3 NA NA NA
LYS D:285 D:285 142.0 0.71 T -50.5 132.6 NA NA NA
LYS E:285 E:285 136.0 0.68 T -57.7 135.8 NA NA NA
LYS F:285 F:285 149.0 0.745 T -64.5 146.4 NA NA NA
LYS G:285 G:285 130.0 0.65 T -68.9 133.9 NA NA NA
LYS H:285 H:285 95.0 0.475 T -66.7 139.9 NA NA NA
LYS I:285 I:285 149.0 0.745 T -19.4 117.5 NA NA NA
LYS J:285 J:285 94.0 0.47 T -41.9 134.7 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 122.0 0.61 T -59.3 132.0 122.0 0.61 0.0 FAD
BTB
SO4
SO4
HOH
 3.847
5.912
3.992
5.478
2.898
 O
HB3
HA
HZ2
HA
 H61A
H62
O2
O4
O
LYS B:307 B:285 119.0 0.595 T -59.4 132.8 119.0 0.595 0.0 FAD
BTB
SO4
HOH
 4.215
5.993
4.281
2.298
 O
H
HA
HE3
 H62A
H82
O3
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 136.0 0.68 T -61.3 131.0 136.0 0.68 0.0 FAD
SO4
HOH
 3.945
3.950
2.796
 O
HA
HA
 H61A
O2
O
LYS B:307 B:285 138.0 0.69 T -60.3 132.0 138.0 0.69 0.0 FAD
SO4
HOH
 4.006
4.150
3.098
 O
HA
O
 H61A
O4
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:285 A:285 101.0 0.505 T -53.8 128.4 101.0 0.505 0.0 SO4
FAD
HOH
 4.316
4.439
2.999
 C
O
N
 O4
N6A
O
LYS B:285 B:285 109.0 0.545 T -43.4 134.4 109.0 0.545 0.0 FAD
HOH
 4.879
5.410
 O
N
 N6A
O
LYS C:285 C:285 131.0 0.655 T -52.5 118.6 NA NA NA
LYS D:285 D:285 106.0 0.53 T -61.6 123.5 NA NA NA
LYS E:285 E:285 138.0 0.69 T -51.8 124.2 NA NA NA
LYS F:285 F:285 96.0 0.48 T -54.5 126.7 NA NA NA
LYS G:285 G:285 133.0 0.665 T -50.7 133.4 NA NA NA
LYS H:285 H:285 105.0 0.525 T -45.4 129.9 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 LYS A:285 A:285 133.0 0.665 T -52.6 129.9 133.0 0.665 0.0 SO4
FAD
HOH
 4.246
4.510
2.944
 C
O
N
 O4
N6A
O
LYS B:285 B:285 117.0 0.585 T -72.1 143.3 117.0 0.585 0.0 SO4
FAD
HOH
 4.205
4.932
3.208
 C
O
N
 O1
N6A
O
LYS C:285 C:285 140.0 0.7 T -59.6 128.4 NA NA NA
LYS D:285 D:285 101.0 0.505 T -54.6 125.2 NA NA NA
LYS E:285 E:285 135.0 0.675 T -51.4 129.1 NA NA NA
LYS F:285 F:285 105.0 0.525 T -54.8 128.3 NA NA NA
LYS G:285 G:285 122.0 0.61 T -50.6 133.8 NA NA NA
LYS H:285 H:285 109.0 0.545 T -47.8 129.2 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 LYS A:285 A:285 140.0 0.7 T -50.3 128.4 140.0 0.7 0.0 SO4
FAD
HOH
 4.825
4.488
3.282
 C
O
N
 O3
N6A
O
LYS B:285 B:285 139.0 0.695 T -50.0 131.3 139.0 0.695 0.0 SO4
FAD
HOH
 3.760
4.807
5.630
 C
O
N
 O2
N6A
O
LYS C:285 C:285 131.0 0.655 T -55.8 133.4 NA NA NA
LYS D:285 D:285 124.0 0.62 T -56.0 125.7 NA NA NA
LYS E:285 E:285 117.0 0.585 T -41.3 126.8 NA NA NA
LYS F:285 F:285 121.0 0.605 T -57.8 133.5 NA NA NA
LYS G:285 G:285 111.0 0.555 T -50.3 134.7 NA NA NA
LYS H:285 H:285 130.0 0.65 T -55.7 127.9 NA NA NA
LYS I:285 I:285 132.0 0.66 T -56.6 128.8 NA NA NA
LYS J:285 J:285 132.0 0.66 T -60.6 128.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 LYS A:306 A:285 130.0 0.65 T -67.9 137.8 130.0 0.65 0.0 FAD
TRS
HOH
 3.728
6.453
2.451
 O
HE2
HA
 H61A
C3
O
LYS B:306 B:285 141.0 0.705 T -64.7 135.8 141.0 0.705 0.0 FAD
HOH
 3.700
3.032
 O
O
 H61A
O
LYS C:306 C:285 121.0 0.605 T -62.0 132.3 NA NA NA
LYS D:306 D:285 111.0 0.555 T -62.1 134.5 NA NA NA
LYS E:306 E:285 133.0 0.665 T -68.4 135.6 NA NA NA
LYS F:306 F:285 129.0 0.645 T -67.5 136.2 NA NA NA
LYS G:306 G:285 119.0 0.595 T -65.4 137.8 NA NA NA
LYS H:306 H:285 125.0 0.625 T -66.3 135.4 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 95.0 0.475 T -60.7 134.0 95.0 0.475 0.0 FAD
SO4
HOH
 3.859
3.996
2.788
 O
HA
HG3
 H61A
O1
O
LYS B:307 B:285 98.0 0.49 T -61.4 134.6 98.0 0.49 0.0 FAD
SO4
HOH
 3.732
4.347
2.893
 O
HA
HG3
 H61A
O4
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 LYS A:307 A:285 132.0 0.66 T -64.3 133.5 132.0 0.66 0.0 FAD
GOL
HOH
 4.634
3.753
2.943
 O
CA
O
 N6A
O2
O
LYS B:307 B:285 106.0 0.53 T -54.7 131.2 106.0 0.53 0.0 FAD
HOH
 4.449
2.936
 O
O
 N6A
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 LYS A:307 A:285 121.0 0.605 T -60.0 130.6 121.0 0.605 0.0 FAD
SO4
HOH
 4.730
4.308
2.915
 O
C
CE
 N6A
O1
O
LYS B:307 B:285 118.0 0.59 T -60.4 129.7 118.0 0.59 0.0 FAD
SO4
HOH
 4.602
4.527
3.015
 O
C
O
 N6A
O3
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 136.0 0.68 T -63.0 130.4 136.0 0.68 0.0 FAD
SO4
BTB
HOH
 3.987
3.881
5.966
2.652
 O
HA
H
HG2
 H61A
O2
H62
O
LYS B:307 B:285 106.0 0.53 T -63.2 133.2 106.0 0.53 0.0 FAD
SO4
BTB
HOH
 3.946
4.011
5.048
2.439
 O
HA
HZ1
HG3
 H61A
O4
H61
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 136.0 0.68 T -62.2 134.6 136.0 0.68 0.0 FAD
SO4
BTB
HOH
 3.936
3.896
6.007
2.774
 O
HA
HB3
HD3
 H62A
O2
H81
O
LYS B:307 B:285 125.0 0.625 T -63.2 135.5 125.0 0.625 0.0 FAD
SO4
BTB
HOH
 4.093
4.019
5.922
2.750
 O
HA
H
HE2
 H61A
O4
H82
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 137.0 0.685 T -62.5 130.9 137.0 0.685 0.0 FAD
SO4
SO4
HOH
 3.984
3.953
6.416
3.052
 O
HA
HZ2
O
 H61A
O2
O4
O
LYS B:307 B:285 106.0 0.53 T -61.1 131.9 106.0 0.53 0.0 FAD
SO4
SO4
HOH
 3.874
4.298
5.975
1.778
 O
HA
HZ2
HZ1
 H61A
O4
O3
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 LYS A:307 A:285 134.0 0.67 T -63.1 132.5 134.0 0.67 0.0 FAD
SO4
HOH
 4.015
3.985
2.816
 O
HA
O
 H61A
O2
O
LYS B:307 B:285 141.0 0.705 T -67.4 138.5 141.0 0.705 0.0 FAD
 3.870
 O
 H61A
LYS C:307 C:285 108.0 0.54 T -64.6 134.9 NA NA NA
LYS D:307 D:285 112.0 0.56 T -63.5 133.3 NA NA NA
LYS E:307 E:285 132.0 0.66 T -61.5 130.0 NA NA NA
LYS F:307 F:285 127.0 0.635 T -62.2 132.7 NA NA NA
LYS G:307 G:285 142.0 0.71 T -65.1 135.6 NA NA NA
LYS H:307 H:285 116.0 0.58 T -62.7 135.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 LYS A:320 A:320 139.0 0.695 T -53.6 138.2