Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557729 . T A CCDS5749.1:NM_000108.3:c.1058aTt>aAt_NP_000099.2:p.353I>N Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 ILE A:339 A:318 1.0 0.006 -145.5 165.9 1.0 0.006 0.0 FAD
HOH
 4.426
3.058
 O
O
 O2P
O
ILE B:339 B:318 0.0 0.0 -153.4 163.7 0.0 0.0 0.0 FAD
HOH
 4.431
5.948
 O
C
 O2P
O
ILE C:339 C:318 0.0 0.0 -133.9 173.9 NA NA NA
ILE D:339 D:318 1.0 0.006 -144.2 165.3 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 ILE A:318 A:318 0.0 0.0 -156.0 160.1 0.0 0.0 0.0 FAD
HOH
 4.864
2.851
 O
O
 O2P
O
ILE B:318 B:318 0.0 0.0 -138.0 172.3 0.0 0.0 0.0 FAD
HOH
 5.242
3.019
 O
O
 O2P
O
ILE C:318 C:318 0.0 0.0 -140.1 -173.9 NA NA NA
ILE D:318 D:318 0.0 0.0 -141.1 165.3 NA NA NA
ILE E:318 E:318 1.0 0.006 -147.1 168.9 NA NA NA
ILE F:318 F:318 0.0 0.0 -155.2 169.0 NA NA NA
ILE G:318 G:318 0.0 0.0 -144.3 168.1 NA NA NA
ILE H:318 H:318 1.0 0.006 -157.2 174.6 NA NA NA
ILE I:318 I:318 0.0 0.0 -141.9 153.0 NA NA NA
ILE J:318 J:318 0.0 0.0 -134.4 174.4 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 1.0 0.006 -143.5 164.8 1.0 0.006 0.0 FAD
HOH
 4.432
2.788
 O
O
 O1P
O
ILE B:340 B:318 1.0 0.006 -146.5 167.7 1.0 0.006 0.0 FAD
HOH
 4.433
2.735
 O
O
 O1P
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 0.0 0.0 -145.3 164.3 0.0 0.0 0.0 FAD
1PE
HOH
 4.350
9.651
2.742
 HD12
HG21
O
 O1P
H161
O
ILE B:340 B:318 1.0 0.006 -146.7 165.8 1.0 0.006 0.0 FAD
HOH
 4.335
2.716
 HD12
O
 O2P
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:318 A:318 1.0 0.006 -143.3 176.3 1.0 0.006 0.0 FAD
HOH
 4.544
2.742
 O
O
 O2P
O
ILE B:318 B:318 1.0 0.006 -141.2 170.1 1.0 0.006 0.0 FAD
HOH
 4.396
2.430
 O
O
 O2P
O
ILE C:318 C:318 0.0 0.0 -135.0 166.8 NA NA NA
ILE D:318 D:318 1.0 0.006 -145.4 172.0 NA NA NA
ILE E:318 E:318 0.0 0.0 -145.1 158.8 NA NA NA
ILE F:318 F:318 0.0 0.0 -142.2 169.4 NA NA NA
ILE G:318 G:318 0.0 0.0 -140.5 172.3 NA NA NA
ILE H:318 H:318 0.0 0.0 -147.7 163.5 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 ILE A:318 A:318 1.0 0.006 -150.2 171.8 1.0 0.006 0.0 FAD
HOH
 4.457
2.778
 O
O
 O2P
O
ILE B:318 B:318 0.0 0.0 -140.3 168.7 0.0 0.0 0.0 FAD
HOH
 4.394
2.530
 O
O
 O2P
O
ILE C:318 C:318 1.0 0.006 -144.1 166.9 NA NA NA
ILE D:318 D:318 1.0 0.006 -151.2 168.2 NA NA NA
ILE E:318 E:318 0.0 0.0 -136.4 164.4 NA NA NA
ILE F:318 F:318 1.0 0.006 -149.7 167.0 NA NA NA
ILE G:318 G:318 0.0 0.0 -148.6 167.5 NA NA NA
ILE H:318 H:318 0.0 0.0 -140.9 168.8 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 ILE A:318 A:318 1.0 0.006 -146.2 167.4 1.0 0.006 0.0 FAD
HOH
 4.376
2.616
 O
O
 O2P
O
ILE B:318 B:318 0.0 0.0 -140.9 168.9 0.0 0.0 0.0 FAD
HOH
 4.319
2.687
 O
O
 O2P
O
ILE C:318 C:318 0.0 0.0 -148.3 170.4 NA NA NA
ILE D:318 D:318 0.0 0.0 -145.1 172.1 NA NA NA
ILE E:318 E:318 0.0 0.0 -145.5 171.3 NA NA NA
ILE F:318 F:318 0.0 0.0 -141.4 179.1 NA NA NA
ILE G:318 G:318 0.0 0.0 -150.3 172.4 NA NA NA
ILE H:318 H:318 0.0 0.0 -145.4 169.9 NA NA NA
ILE I:318 I:318 0.0 0.0 -146.6 172.6 NA NA NA
ILE J:318 J:318 0.0 0.0 -140.5 176.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 ILE A:339 A:318 0.0 0.0 -146.3 166.1 0.0 0.0 0.0 FAD
HOH
 4.322
2.572
 O
O
 O2P
O
ILE B:339 B:318 1.0 0.006 -144.3 166.2 1.0 0.006 0.0 FAD
HOH
 4.424
2.693
 O
O
 O2P
O
ILE C:339 C:318 0.0 0.0 -145.9 166.5 NA NA NA
ILE D:339 D:318 0.0 0.0 -147.8 165.3 NA NA NA
ILE E:339 E:318 1.0 0.006 -148.4 168.3 NA NA NA
ILE F:339 F:318 0.0 0.0 -146.0 166.9 NA NA NA
ILE G:339 G:318 0.0 0.0 -147.5 167.4 NA NA NA
ILE H:339 H:318 0.0 0.0 -144.6 167.3 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 1.0 0.006 -144.3 163.4 1.0 0.006 0.0 FAD
1PE
HOH
 4.393
9.829
2.754
 O
HG21
O
 O1P
H122
O
ILE B:340 B:318 0.0 0.0 -146.3 164.1 0.0 0.0 0.0 FAD
HOH
 4.439
2.733
 O
O
 O2P
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 ILE A:340 A:318 0.0 0.0 -139.2 169.1 0.0 0.0 0.0 FAD
HOH
 4.468
2.682
 O
O
 O2P
O
ILE B:340 B:318 0.0 0.0 -152.5 170.7 0.0 0.0 0.0 FAD
HOH
 4.337
2.594
 O
O
 O2P
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 ILE A:340 A:318 1.0 0.006 -144.5 161.5 1.0 0.006 0.0 FAD
HOH
 4.419
2.692
 O
O
 O2P
O
ILE B:340 B:318 1.0 0.006 -142.6 163.9 1.0 0.006 0.0 FAD
HOH
 4.434
2.629
 O
O
 O2P
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 1.0 0.006 -144.8 165.7 1.0 0.006 0.0 FAD
HOH
 4.460
2.756
 O
O
 O2P
O
ILE B:340 B:318 0.0 0.0 -144.7 165.6 0.0 0.0 0.0 FAD
HOH
 4.422
2.733
 O
O
 O1P
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 1.0 0.006 -148.3 164.3 1.0 0.006 0.0 FAD
HOH
 4.400
2.711
 O
O
 O2P
O
ILE B:340 B:318 1.0 0.006 -149.6 167.1 1.0 0.006 0.0 FAD
HOH
 4.425
2.756
 O
O
 O1P
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 1.0 0.006 -147.2 163.7 1.0 0.006 0.0 FAD
HOH
 4.410
2.772
 O
O
 O2P
O
ILE B:340 B:318 0.0 0.0 -146.8 164.8 0.0 0.0 0.0 FAD
HOH
 4.431
2.718
 O
O
 O1P
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 ILE A:340 A:318 0.0 0.0 -144.3 168.6 0.0 0.0 0.0 FAD
HOH
 4.419
2.670
 O
O
 O1P
O
ILE B:340 B:318 0.0 0.0 -145.9 168.8 0.0 0.0 0.0 FAD
HOH
 4.492
7.105
 O
HG21
 O1P
O
ILE C:340 C:318 0.0 0.0 -145.6 169.9 NA NA NA
ILE D:340 D:318 0.0 0.0 -145.2 169.1 NA NA NA
ILE E:340 E:318 0.0 0.0 -144.1 170.5 NA NA NA
ILE F:340 F:318 0.0 0.0 -144.1 170.0 NA NA NA
ILE G:340 G:318 0.0 0.0 -144.2 169.6 NA NA NA
ILE H:340 H:318 1.0 0.006 -144.0 166.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 ILE A:353 A:353 1.0 0.006 -142.5 166.3