Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557752 . A C CCDS5749.1:NM_000108.3:c.1081Atg>Ctg_NP_000099.2:p.361M>L Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 MET A:347 A:326 74.0 0.4 -79.6 69.8 74.0 0.4 0.0 BME
FAD
HOH
 8.375
3.014
3.526
 CE
O
CG
 C1
O3'
O
MET B:347 B:326 57.0 0.308 -82.2 75.8 57.0 0.308 0.0 BME
FAD
HOH
 8.177
3.101
3.948
 CE
O
CA
 C1
O3'
O
MET C:347 C:326 61.0 0.33 -81.6 76.1 NA NA NA
MET D:347 D:326 76.0 0.411 -82.1 68.6 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 MET A:326 A:326 70.0 0.378 -85.3 66.8 70.0 0.378 0.0 FAD
HOH
 2.711
3.009
 O
CE
 O3'
O
MET B:326 B:326 88.0 0.476 -86.2 82.8 88.0 0.476 0.0 FAD
HOH
 3.114
3.393
 O
CA
 O3'
O
MET C:326 C:326 87.0 0.47 -87.7 79.7 NA NA NA
MET D:326 D:326 91.0 0.492 -94.4 71.7 NA NA NA
MET E:326 E:326 74.0 0.4 -97.3 82.0 NA NA NA
MET F:326 F:326 75.0 0.405 -88.2 75.9 NA NA NA
MET G:326 G:326 68.0 0.368 -80.6 77.8 NA NA NA
MET H:326 H:326 85.0 0.459 -67.5 89.3 NA NA NA
MET I:326 I:326 68.0 0.368 -101.8 57.6 NA NA NA
MET J:326 J:326 83.0 0.449 -82.1 74.7 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 MET A:348 A:326 76.0 0.411 -82.0 81.7 76.0 0.411 0.0 FAD
HOH
 2.753
2.496
 O
H
 HO3'
O
MET B:348 B:326 72.0 0.389 -82.7 80.4 72.0 0.389 0.0 FAD
BTB
SO4
HOH
 2.552
8.734
5.992
2.186
 O
HE1
HG3
H
 HO3'
H31
O2
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:348 A:326 83.0 0.449 -85.9 81.2 83.0 0.449 0.0 FAD
HOH
 2.645
2.756
 O
O
 HO3'
O
MET B:348 B:326 71.0 0.384 -84.7 84.3 71.0 0.384 0.0 FAD
SO4
HOH
 2.711
6.096
2.619
 O
HG3
HE2
 HO3'
O2
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 MET A:326 A:326 54.0 0.292 -82.2 80.9 54.0 0.292 0.0 SO4
FAD
NAD
HOH
 6.910
3.327
3.737
3.150
 N
O
SD
CG
 O2
O3'
O3D
O
MET B:326 B:326 61.0 0.33 -88.5 72.6 61.0 0.33 0.0 SO4
FAD
NAD
HOH
 6.929
3.244
6.567
3.032
 CG
O
SD
N
 O4
O3'
O2N
O
MET C:326 C:326 63.0 0.341 -84.0 73.5 NA NA NA
MET D:326 D:326 57.0 0.308 -81.6 72.5 NA NA NA
MET E:326 E:326 74.0 0.4 -85.9 71.9 NA NA NA
MET F:326 F:326 72.0 0.389 -82.5 74.9 NA NA NA
MET G:326 G:326 74.0 0.4 -81.9 81.3 NA NA NA
MET H:326 H:326 73.0 0.395 -86.8 67.6 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 MET A:326 A:326 73.0 0.395 -84.7 76.8 73.0 0.395 0.0 SO4
FAD
NAI
HOH
 6.821
3.266
2.919
3.193
 CG
O
O
N
 O2
O3'
O3D
O
MET B:326 B:326 69.0 0.373 -85.7 78.0 69.0 0.373 0.0 SO4
FAD
NAI
HOH
 6.403
3.360
2.751
2.914
 CG
O
O
N
 O4
O3'
O3D
O
MET C:326 C:326 71.0 0.384 -84.8 76.9 NA NA NA
MET D:326 D:326 74.0 0.4 -83.1 79.8 NA NA NA
MET E:326 E:326 71.0 0.384 -81.0 76.4 NA NA NA
MET F:326 F:326 71.0 0.384 -81.2 79.2 NA NA NA
MET G:326 G:326 72.0 0.389 -84.9 77.1 NA NA NA
MET H:326 H:326 72.0 0.389 -85.5 76.8 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 MET A:326 A:326 75.0 0.405 -85.2 70.4 75.0 0.405 0.0 SO4
FAD
HOH
 6.531
3.191
3.042
 CG
O
N
 O2
O3'
O
MET B:326 B:326 74.0 0.4 -83.4 66.6 74.0 0.4 0.0 SO4
FAD
HOH
 6.791
2.919
3.593
 N
O
CG
 O4
O3'
O
MET C:326 C:326 69.0 0.373 -80.3 72.9 NA NA NA
MET D:326 D:326 69.0 0.373 -80.0 75.7 NA NA NA
MET E:326 E:326 73.0 0.395 -86.2 76.2 NA NA NA
MET F:326 F:326 72.0 0.389 -78.9 83.4 NA NA NA
MET G:326 G:326 75.0 0.405 -85.2 76.9 NA NA NA
MET H:326 H:326 70.0 0.378 -77.6 76.7 NA NA NA
MET I:326 I:326 75.0 0.405 -83.2 78.9 NA NA NA
MET J:326 J:326 72.0 0.389 -77.5 74.8 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 MET A:347 A:326 70.0 0.378 -86.1 76.3 70.0 0.378 0.0 FAD
TRS
HOH
 3.007
9.901
2.397
 O
HE1
HG3
 H1'2
C1
O
MET B:347 B:326 70.0 0.378 -85.4 75.9 70.0 0.378 0.0 FAD
HOH
 3.073
2.749
 O
HG2
 H1'2
O
MET C:347 C:326 59.0 0.319 -84.9 74.8 NA NA NA
MET D:347 D:326 77.0 0.416 -84.9 74.1 NA NA NA
MET E:347 E:326 70.0 0.378 -85.0 76.2 NA NA NA
MET F:347 F:326 71.0 0.384 -84.2 75.1 NA NA NA
MET G:347 G:326 61.0 0.33 -82.9 76.6 NA NA NA
MET H:347 H:326 67.0 0.362 -83.7 76.3 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:348 A:326 73.0 0.395 -85.4 82.3 73.0 0.395 0.0 FAD
SO4
HOH
 2.800
6.012
2.139
 O
HG3
H
 HO3'
O4
O
MET B:348 B:326 71.0 0.384 -84.9 82.3 71.0 0.384 0.0 FAD
SO4
HOH
 2.885
5.992
2.217
 O
HG3
H
 H1'2
O1
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 MET A:348 A:326 76.0 0.411 -85.1 80.7 76.0 0.411 0.0 FAD
PO4
HOH
 3.247
6.592
2.882
 O
CG
N
 O3'
O4
O
MET B:348 B:326 69.0 0.373 -86.7 87.3 69.0 0.373 0.0 PO4
HOH
 6.809
3.436
 CG
CE
 O1
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 MET A:348 A:326 73.0 0.395 -81.6 82.5 73.0 0.395 0.0 FAD
SO4
HOH
 3.258
6.829
2.520
 C
CG
O
 O3'
O4
O
MET B:348 B:326 72.0 0.389 -79.8 84.2 72.0 0.389 0.0 FAD
SO4
SO4
HOH
 3.258
7.422
6.966
2.755
 C
SD
CG
O
 O3'
O2
O1
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:348 A:326 73.0 0.395 -86.6 80.7 73.0 0.395 0.0 FAD
SO4
BTB
HOH
 3.112
5.947
8.581
2.284
 O
HG3
HE1
H
 H1'2
O4
HO1
O
MET B:348 B:326 72.0 0.389 -86.1 80.9 72.0 0.389 0.0 FAD
SO4
BTB
HOH
 3.017
6.025
8.682
2.138
 O
HG3
HE1
H
 H1'1
O2
HO4
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:348 A:326 73.0 0.395 -83.5 80.7 73.0 0.395 0.0 FAD
SO4
BTB
HOH
 2.685
6.012
8.747
2.403
 O
HG3
HE1
H
 HO3'
O4
HO3
O
MET B:348 B:326 74.0 0.4 -85.0 79.8 74.0 0.4 0.0 FAD
SO4
BTB
HOH
 2.652
5.908
8.927
2.101
 O
HG3
HE1
H
 HO3'
O2
HO4
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:348 A:326 74.0 0.4 -86.0 83.0 74.0 0.4 0.0 FAD
SO4
HOH
 2.966
6.046
2.074
 O
HG3
H
 H1'1
O4
O
MET B:348 B:326 72.0 0.389 -84.8 85.0 72.0 0.389 0.0 FAD
SO4
SO4
HOH
 3.074
6.197
8.981
2.127
 O
HG3
HE1
H
 H1'2
O2
O4
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 MET A:348 A:326 81.0 0.438 -86.5 76.8 81.0 0.438 0.0 FAD
SO4
HOH
 3.005
6.000
2.990
 O
HG3
HA
 H1'2
O1
O
MET B:348 B:326 57.0 0.308 -87.1 79.9 57.0 0.308 0.0 FAD
SO4
HOH
 2.887
5.612
9.473
 O
HG3
N
 H1'2
O3
O
MET C:348 C:326 74.0 0.4 -85.3 78.6 NA NA NA
MET D:348 D:326 70.0 0.378 -85.9 81.2 NA NA NA
MET E:348 E:326 70.0 0.378 -87.2 78.3 NA NA NA
MET F:348 F:326 70.0 0.378 -87.6 81.5 NA NA NA
MET G:348 G:326 73.0 0.395 -87.8 79.4 NA NA NA
MET H:348 H:326 71.0 0.384 -88.8 82.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 MET A:361 A:361 68.0 0.368 -84.1 70.3