Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557794 . G A CCDS5749.1:NM_000108.3:c.1123Gaa>Aaa_NP_000099.2:p.375E>K Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 GLU A:361 A:340 72.0 0.379 H -60.6 -40.0 29.0 0.153 0.226 B:P09622:0.226
 HOH
 5.009
 C
 O
GLU B:361 B:340 71.0 0.374 H -58.2 -32.5 29.0 0.153 0.221 A:P09622:0.221
 HOH
 9.335
 OE1
 O
GLU C:361 C:340 76.0 0.4 H -60.0 -31.5 NA NA NA
GLU D:361 D:340 71.0 0.374 H -66.3 -30.4 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 GLU A:340 A:340 77.0 0.405 H -55.7 -31.2 41.0 0.216 0.189 B:P09622:0.189
 HOH
 5.432
 C
 O
GLU B:340 B:340 76.0 0.4 H -52.2 -37.7 36.0 0.189 0.211 K:O00330:0.079
A:P09622:0.211
 HOH
 5.334
 C
 O
GLU C:340 C:340 68.0 0.358 H -48.3 -40.4 NA NA NA
GLU D:340 D:340 77.0 0.405 H -90.1 -36.2 NA NA NA
GLU E:340 E:340 70.0 0.368 H -58.2 -32.7 NA NA NA
GLU F:340 F:340 70.0 0.368 H -67.0 -20.8 NA NA NA
GLU G:340 G:340 70.0 0.368 H -53.1 -19.0 NA NA NA
GLU H:340 H:340 64.0 0.337 H -61.6 -29.1 NA NA NA
GLU I:340 I:340 66.0 0.347 H -76.7 -45.7 NA NA NA
GLU J:340 J:340 69.0 0.363 T -60.1 -32.8 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 68.0 0.358 H -63.4 -38.8 28.0 0.147 0.211 B:P09622:0.211
 HOH
 2.795
 OE2
 O
GLU B:362 B:340 71.0 0.374 H -62.9 -39.2 27.0 0.142 0.232 A:P09622:0.232
 HOH
 5.536
 C
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 75.0 0.395 H -57.9 -42.7 31.0 0.163 0.232 B:P09622:0.232
 1PE
HOH
 2.482
2.672
 HG2
OE1
 H132
O
GLU B:362 B:340 70.0 0.368 H -56.8 -39.8 27.0 0.142 0.226 A:P09622:0.226
 HOH
 4.882
 OE1
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:340 A:340 67.0 0.353 H -69.0 -33.2 24.0 0.126 0.227 B:P09622:0.226
 HOH
 2.760
 OE2
 O
GLU B:340 B:340 71.0 0.374 H -62.6 -35.3 30.0 0.158 0.216 A:P09622:0.216
 HOH
 3.169
 OE2
 O
GLU C:340 C:340 68.0 0.358 H -63.6 -26.0 NA NA NA
GLU D:340 D:340 71.0 0.374 H -71.1 -37.5 NA NA NA
GLU E:340 E:340 66.0 0.347 H -79.0 -18.6 NA NA NA
GLU F:340 F:340 68.0 0.358 H -70.5 -36.1 NA NA NA
GLU G:340 G:340 64.0 0.337 H -62.8 -36.8 NA NA NA
GLU H:340 H:340 69.0 0.363 H -66.4 -35.1 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 GLU A:340 A:340 70.0 0.368 H -61.9 -36.1 24.0 0.126 0.242 B:P09622:0.242
 HOH
 2.620
 OE2
 O
GLU B:340 B:340 68.0 0.358 H -71.4 -37.3 28.0 0.147 0.211 A:P09622:0.211
 HOH
 3.217
 OE2
 O
GLU C:340 C:340 65.0 0.342 H -70.1 -31.2 NA NA NA
GLU D:340 D:340 69.0 0.363 H -63.8 -37.1 NA NA NA
GLU E:340 E:340 66.0 0.347 H -67.1 -33.3 NA NA NA
GLU F:340 F:340 70.0 0.368 H -67.1 -35.8 NA NA NA
GLU G:340 G:340 65.0 0.342 H -64.0 -36.7 NA NA NA
GLU H:340 H:340 66.0 0.347 H -63.2 -36.7 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 GLU A:340 A:340 70.0 0.368 H -65.2 -34.2 24.0 0.126 0.242 K:O00330:0.084
B:P09622:0.226
GLU B:340 B:340 71.0 0.374 H -62.2 -44.1 33.0 0.174 0.2 A:P09622:0.2
 HOH
 6.969
 OE2
 O
GLU C:340 C:340 67.0 0.353 H -66.2 -28.2 NA NA NA
GLU D:340 D:340 69.0 0.363 H -60.4 -39.2 NA NA NA
GLU E:340 E:340 66.0 0.347 H -67.4 -33.6 NA NA NA
GLU F:340 F:340 68.0 0.358 H -63.2 -34.2 NA NA NA
GLU G:340 G:340 68.0 0.358 H -64.4 -32.1 NA NA NA
GLU H:340 H:340 68.0 0.358 H -65.4 -35.7 NA NA NA
GLU I:340 I:340 67.0 0.353 H -62.4 -30.9 NA NA NA
GLU J:340 J:340 67.0 0.353 H -61.1 -37.5 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 GLU A:361 A:340 71.0 0.374 H -62.6 -35.1 38.0 0.2 0.174 B:P09622:0.174
 HOH
 5.127
 C
 O
GLU B:361 B:340 64.0 0.337 H -62.7 -36.3 27.0 0.142 0.195 A:P09622:0.195
 HOH
 4.827
 O
 O
GLU C:361 C:340 64.0 0.337 H -61.8 -37.1 NA NA NA
GLU D:361 D:340 68.0 0.358 H -61.6 -36.5 NA NA NA
GLU E:361 E:340 68.0 0.358 H -63.0 -36.2 NA NA NA
GLU F:361 F:340 67.0 0.353 H -61.5 -35.6 NA NA NA
GLU G:361 G:340 64.0 0.337 H -61.8 -34.6 NA NA NA
GLU H:361 H:340 73.0 0.384 H -61.7 -35.7 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 76.0 0.4 H -59.6 -41.2 31.0 0.163 0.237 B:P09622:0.237
 1PE
HOH
 2.527
2.653
 OE2
OE2
 H141
O
GLU B:362 B:340 70.0 0.368 H -57.8 -39.6 26.0 0.137 0.231 A:P09622:0.232
 HOH
 3.217
 OE2
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 GLU A:362 A:340 70.0 0.368 H -51.9 -38.9 28.0 0.147 0.221 B:P09622:0.221
 GOL
HOH
 7.564
2.819
 OE1
O
 O1
O
GLU B:362 B:340 65.0 0.342 H -56.3 -43.8 63.0 0.332 0.01 A:P09622:0.011
 HOH
 2.739
 OE2
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 GLU A:362 A:340 64.0 0.337 H -52.4 -40.8 24.0 0.126 0.211 B:P09622:0.211
 HOH
 2.615
 OE1
 O
GLU B:362 B:340 63.0 0.332 H -57.7 -41.8 23.0 0.121 0.211 A:P09622:0.211
 HOH
 2.648
 OE1
 O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 64.0 0.337 H -62.4 -38.0 25.0 0.132 0.205 B:P09622:0.205
 HOH
 2.667
 OE1
 O
GLU B:362 B:340 66.0 0.347 H -62.2 -37.6 25.0 0.132 0.215 A:P09622:0.216
 HOH
 2.587
 OE1
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 67.0 0.353 H -59.1 -40.1 25.0 0.132 0.221 B:P09622:0.221
 HOH
 2.771
 OE2
 O
GLU B:362 B:340 70.0 0.368 H -59.5 -38.2 27.0 0.142 0.226 A:P09622:0.226
 HOH
 2.948
 OE1
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 66.0 0.347 H -60.0 -39.2 64.0 0.337 0.01 B:P09622:0.011
 HOH
 2.631
 OE2
 O
GLU B:362 B:340 66.0 0.347 H -58.5 -40.1 64.0 0.337 0.01 A:P09622:0.011
 HOH
 2.724
 OE2
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 GLU A:362 A:340 67.0 0.353 H -65.6 -36.4 23.0 0.121 0.232 B:P09622:0.232
 HOH
 3.143
 OE1
 O
GLU B:362 B:340 66.0 0.347 H -65.7 -36.8 24.0 0.126 0.221 A:P09622:0.221
 HOH
 4.807
 C
 O
GLU C:362 C:340 69.0 0.363 H -63.9 -36.3 NA NA NA
GLU D:362 D:340 66.0 0.347 H -63.0 -35.2 NA NA NA
GLU E:362 E:340 66.0 0.347 H -64.7 -36.6 NA NA NA
GLU F:362 F:340 62.0 0.326 H -65.3 -34.4 NA NA NA
GLU G:362 G:340 60.0 0.316 H -65.0 -35.8 NA NA NA
GLU H:362 H:340 62.0 0.326 H -64.8 -35.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 GLU A:375 A:375 58.0 0.305 H -62.8 -40.9