Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557829 . C A CCDS5749.1:NM_000108.3:c.1158taC>taA_NP_000099.2:p.386Y>* Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 TYR A:372 A:351 77.0 0.335 G -69.9 -20.0 77.0 0.335 0.0 HOH
 4.249
 OH
 O
TYR B:372 B:351 76.0 0.33 G -67.4 -20.1 76.0 0.33 0.0 HOH
 8.024
 CE1
 O
TYR C:372 C:351 73.0 0.317 G -58.9 -27.0 NA NA NA
TYR D:372 D:351 76.0 0.33 G -66.0 -17.9 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 TYR A:351 A:351 82.0 0.357 G -75.9 -11.6 82.0 0.357 0.0 HOH
 5.530
 O
 O
TYR B:351 B:351 85.0 0.37 G -65.3 -2.5 85.0 0.37 0.0 HOH
 8.177
 CE1
 O
TYR C:351 C:351 87.0 0.378 G -63.6 -11.4 NA NA NA
TYR D:351 D:351 95.0 0.413 T -66.1 -4.4 NA NA NA
TYR E:351 E:351 82.0 0.357 G -76.0 -14.1 NA NA NA
TYR F:351 F:351 91.0 0.396 G -62.2 -18.2 NA NA NA
TYR G:351 G:351 85.0 0.37 T -84.1 -6.3 NA NA NA
TYR H:351 H:351 80.0 0.348 G -62.9 -10.1 NA NA NA
TYR I:351 I:351 83.0 0.361 S -90.5 -40.0 NA NA NA
TYR J:351 J:351 83.0 0.361 T -62.1 7.4 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 88.0 0.383 G -69.8 -17.4 88.0 0.383 0.0 SO4
HOH
 6.552
2.706
 HD2
OH
 O3
O
TYR B:373 B:351 86.0 0.374 G -68.4 -16.1 86.0 0.374 0.0 SO4
HOH
 6.204
3.313
 HD2
OH
 O1
O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 89.0 0.387 G -68.6 -17.4 89.0 0.387 0.0 SO4
1PE
HOH
 7.234
9.366
2.320
 HB3
HH
H
 O3
H161
O
TYR B:373 B:351 90.0 0.391 G -69.1 -15.7 90.0 0.391 0.0 SO4
HOH
 7.550
2.705
 HB3
HE2
 O1
O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 TYR A:351 A:351 88.0 0.383 G -59.0 -9.1 88.0 0.383 0.0 SO4
HOH
 7.286
2.793
 CD2
OH
 O1
O
TYR B:351 B:351 82.0 0.357 T -62.3 -2.3 82.0 0.357 0.0 SO4
HOH
 6.831
2.981
 CD2
O
 O1
O
TYR C:351 C:351 88.0 0.383 T -61.7 -0.0 NA NA NA
TYR D:351 D:351 88.0 0.383 G -60.4 -20.4 NA NA NA
TYR E:351 E:351 85.0 0.37 G -58.0 -8.6 NA NA NA
TYR F:351 F:351 84.0 0.365 G -60.0 -19.9 NA NA NA
TYR G:351 G:351 84.0 0.365 G -61.5 -14.1 NA NA NA
TYR H:351 H:351 82.0 0.357 G -59.5 -18.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 TYR A:351 A:351 83.0 0.361 G -61.6 -13.5 83.0 0.361 0.0 SO4
HOH
 6.515
2.961
 CD2
OH
 O3
O
TYR B:351 B:351 84.0 0.365 G -62.1 -14.7 84.0 0.365 0.0 SO4
HOH
 6.619
3.489
 CD2
O
 O1
O
TYR C:351 C:351 86.0 0.374 G -61.6 -17.5 NA NA NA
TYR D:351 D:351 83.0 0.361 G -62.3 -15.7 NA NA NA
TYR E:351 E:351 80.0 0.348 G -60.2 -15.2 NA NA NA
TYR F:351 F:351 83.0 0.361 G -65.2 -19.2 NA NA NA
TYR G:351 G:351 82.0 0.357 G -64.9 -17.5 NA NA NA
TYR H:351 H:351 82.0 0.357 G -59.9 -16.9 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 TYR A:351 A:351 86.0 0.374 G -64.3 -12.3 86.0 0.374 0.0 SO4
HOH
 8.022
3.226
 CD2
OH
 O3
O
TYR B:351 B:351 86.0 0.374 T -55.1 2.6 86.0 0.374 0.0 SO4
 7.823
 CD2
 O1
TYR C:351 C:351 82.0 0.357 G -64.7 -11.1 NA NA NA
TYR D:351 D:351 81.0 0.352 G -65.2 -18.3 NA NA NA
TYR E:351 E:351 85.0 0.37 G -66.0 -6.2 NA NA NA
TYR F:351 F:351 84.0 0.365 G -66.1 -17.4 NA NA NA
TYR G:351 G:351 87.0 0.378 G -64.8 -12.5 NA NA NA
TYR H:351 H:351 87.0 0.378 G -62.1 -17.7 NA NA NA
TYR I:351 I:351 84.0 0.365 G -68.4 -13.8 NA NA NA
TYR J:351 J:351 84.0 0.365 G -60.1 -20.8 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 TYR A:372 A:351 81.0 0.352 G -63.7 -13.5 81.0 0.352 0.0 HOH
 3.477
 O
 O
TYR B:372 B:351 81.0 0.352 G -65.6 -17.1 81.0 0.352 0.0 HOH
 6.643
 HE1
 O
TYR C:372 C:351 79.0 0.343 G -64.0 -13.6 NA NA NA
TYR D:372 D:351 83.0 0.361 G -64.9 -14.6 NA NA NA
TYR E:372 E:351 77.0 0.335 G -62.5 -12.0 NA NA NA
TYR F:372 F:351 83.0 0.361 G -65.2 -16.3 NA NA NA
TYR G:372 G:351 79.0 0.343 G -65.0 -14.4 NA NA NA
TYR H:372 H:351 79.0 0.343 G -64.9 -12.6 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 88.0 0.383 G -68.0 -17.0 88.0 0.383 0.0 SO4
1PE
HOH
 6.883
9.606
2.134
 HB3
HE1
H
 O3
H122
O
TYR B:373 B:351 92.0 0.4 G -69.9 -13.6 92.0 0.4 0.0 SO4
SO4
HOH
 7.067
9.358
3.214
 HB3
N
O
 O2
O2
O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 TYR A:373 A:351 82.0 0.357 G -69.4 -22.8 82.0 0.357 0.0 PO4
GOL
HOH
 6.361
4.846
2.715
 CD2
N
N
 O3
O3
O
TYR B:373 B:351 77.0 0.335 G -63.5 -15.6 77.0 0.335 0.0 PO4
HOH
 6.026
2.811
 CD2
OH
 O2
O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 TYR A:373 A:351 90.0 0.391 G -65.6 -22.0 90.0 0.391 0.0 SO4
HOH
 6.644
3.003
 CD2
N
 O3
O
TYR B:373 B:351 93.0 0.404 G -62.7 -22.8 93.0 0.404 0.0 SO4
HOH
 7.723
2.980
 CG
O
 O2
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 86.0 0.374 G -65.3 -21.0 86.0 0.374 0.0 SO4
HOH
 6.413
2.153
 HD2
H
 O3
O
TYR B:373 B:351 91.0 0.396 G -66.1 -20.3 91.0 0.396 0.0 SO4
SO4
HOH
 7.162
9.025
2.871
 HB3
H
HE2
 O1
O3
O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 89.0 0.387 G -66.3 -19.7 89.0 0.387 0.0 SO4
HOH
 6.518
2.090
 HD2
H
 O3
O
TYR B:373 B:351 89.0 0.387 G -65.9 -15.5 89.0 0.387 0.0 SO4
HOH
 6.579
3.015
 HD2
OH
 O1
O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 91.0 0.396 G -69.7 -17.2 91.0 0.396 0.0 SO4
HOH
 6.889
2.139
 HB3
H
 O3
O
TYR B:373 B:351 92.0 0.4 G -70.2 -16.3 92.0 0.4 0.0 SO4
HOH
 7.126
2.526
 HB3
HE2
 O1
O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TYR A:373 A:351 84.0 0.365 G -67.8 -15.8 84.0 0.365 0.0 SO4
HOH
 6.553
3.223
 HB3
OH
 O4
O
TYR B:373 B:351 87.0 0.378 G -70.4 -14.3 87.0 0.378 0.0 SO4
HOH
 6.982
5.262
 HB3
HD2
 O2
O
TYR C:373 C:351 87.0 0.378 G -69.3 -16.6 NA NA NA
TYR D:373 D:351 85.0 0.37 G -70.2 -14.3 NA NA NA
TYR E:373 E:351 88.0 0.383 G -67.4 -16.5 NA NA NA
TYR F:373 F:351 88.0 0.383 G -68.8 -14.9 NA NA NA
TYR G:373 G:351 83.0 0.361 G -67.9 -17.0 NA NA NA
TYR H:373 H:351 89.0 0.387 G -68.9 -15.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 TYR A:386 A:386 92.0 0.4 G -62.9 -17.5