Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 107557874 . G A CCDS5749.1:NM_000108.3:c.1203tgG>tgA_NP_000099.2:p.401W>* Homo sapiens dihydrolipoamide dehydrogenase (DLD), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3rnm 1 P09622 99.37 0.0 X-RAY
 2011-05-04 TRP A:387 A:366 15.0 0.059 E -161.7 158.9 15.0 0.059 0.0 HOH
 2.741
 NE1
 O
TRP B:387 B:366 15.0 0.059 E -161.2 156.3 15.0 0.059 0.0 HOH
 3.473
 CG
 O
TRP C:387 C:366 14.0 0.055 E -159.9 151.7 NA NA NA
TRP D:387 D:366 16.0 0.063 E -157.8 159.5 NA NA NA
1zy8 1 P09622 100.0 0.0 X-RAY
 2005-11-15 TRP A:366 A:366 15.0 0.059 E -150.5 160.6 15.0 0.059 0.0 HOH
 3.213
 O
 O
TRP B:366 B:366 16.0 0.063 E -149.0 167.8 16.0 0.063 0.0 HOH
 3.635
 CD2
 O
TRP C:366 C:366 16.0 0.063 E -150.4 157.7 NA NA NA
TRP D:366 D:366 18.0 0.071 E -163.8 154.9 NA NA NA
TRP E:366 E:366 15.0 0.059 E -155.7 165.2 NA NA NA
TRP F:366 F:366 20.0 0.078 E -159.7 161.4 NA NA NA
TRP G:366 G:366 17.0 0.067 E -175.3 162.3 NA NA NA
TRP H:366 H:366 19.0 0.075 E -156.5 165.1 NA NA NA
TRP I:366 I:366 18.0 0.071 E -160.9 140.0 NA NA NA
TRP J:366 J:366 13.0 0.051 E -152.7 150.4 NA NA NA
6i4q 1 P09622 100.0 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 19.0 0.075 E -152.6 162.2 19.0 0.075 0.0 HOH
 2.221
 HE1
 O
TRP B:388 B:366 19.0 0.075 E -151.2 160.0 19.0 0.075 0.0 HOH
 1.999
 HE1
 O
6i4t 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 18.0 0.071 E -155.8 160.1 18.0 0.071 0.0 HOH
 2.118
 HE1
 O
TRP B:388 B:366 17.0 0.067 E -154.5 157.9 17.0 0.067 0.0 HOH
 1.998
 HE1
 O
1zmc 1 P09622 99.79 0.0 X-RAY
 2005-06-28 TRP A:366 A:366 18.0 0.071 E -153.0 160.5 18.0 0.071 0.0 NAD
HOH
 8.187
3.348
 CZ2
CD2
 O2N
O
TRP B:366 B:366 16.0 0.063 E -153.9 158.4 16.0 0.063 0.0 NAD
HOH
 7.039
3.581
 CZ2
CD2
 O5D
O
TRP C:366 C:366 15.0 0.059 E -156.3 159.8 NA NA NA
TRP D:366 D:366 17.0 0.067 E -158.6 160.3 NA NA NA
TRP E:366 E:366 14.0 0.055 E -157.1 164.1 NA NA NA
TRP F:366 F:366 19.0 0.075 E -163.0 157.3 NA NA NA
TRP G:366 G:366 20.0 0.078 E -156.5 159.8 NA NA NA
TRP H:366 H:366 15.0 0.059 E -158.2 163.0 NA NA NA
1zmd 1 P09622 99.79 0.0 X-RAY
 2005-06-28 TRP A:366 A:366 16.0 0.063 E -152.0 159.0 16.0 0.063 0.0 NAI
HOH
 7.620
3.487
 CH2
CD2
 O2D
O
TRP B:366 B:366 17.0 0.067 E -158.2 160.1 17.0 0.067 0.0 NAI
HOH
 7.664
3.485
 CH2
CG
 O2D
O
TRP C:366 C:366 17.0 0.067 E -160.0 160.0 NA NA NA
TRP D:366 D:366 17.0 0.067 E -150.8 160.9 NA NA NA
TRP E:366 E:366 18.0 0.071 E -153.9 162.4 NA NA NA
TRP F:366 F:366 19.0 0.075 E -153.8 162.3 NA NA NA
TRP G:366 G:366 20.0 0.078 E -157.2 160.6 NA NA NA
TRP H:366 H:366 16.0 0.063 E -154.2 160.0 NA NA NA
2f5z 1 P09622 99.79 0.0 X-RAY
 2006-01-17 TRP A:366 A:366 15.0 0.059 E -158.2 159.0 15.0 0.059 0.0 HOH
 3.307
 CD2
 O
TRP B:366 B:366 18.0 0.071 E -160.5 161.2 18.0 0.071 0.0 HOH
 7.419
 CH2
 O
TRP C:366 C:366 17.0 0.067 E -153.7 159.1 NA NA NA
TRP D:366 D:366 16.0 0.063 E -156.5 161.1 NA NA NA
TRP E:366 E:366 18.0 0.071 E -156.7 159.3 NA NA NA
TRP F:366 F:366 15.0 0.059 E -156.5 165.1 NA NA NA
TRP G:366 G:366 14.0 0.055 E -160.4 162.3 NA NA NA
TRP H:366 H:366 16.0 0.063 E -156.7 159.4 NA NA NA
TRP I:366 I:366 16.0 0.063 E -158.6 161.4 NA NA NA
TRP J:366 J:366 16.0 0.063 E -147.0 165.6 NA NA NA
5nhg 1 P09622 100.0 0.0 X-RAY
 2018-05-16 TRP A:387 A:366 15.0 0.059 E -154.8 158.3 15.0 0.059 0.0 HOH
 2.837
 HZ2
 O
TRP B:387 B:366 18.0 0.071 E -153.7 158.4 18.0 0.071 0.0 HOH
 3.079
 HB3
 O
TRP C:387 C:366 14.0 0.055 E -154.7 156.8 NA NA NA
TRP D:387 D:366 15.0 0.059 E -155.4 157.5 NA NA NA
TRP E:387 E:366 14.0 0.055 E -155.2 158.0 NA NA NA
TRP F:387 F:366 16.0 0.063 E -154.0 158.2 NA NA NA
TRP G:387 G:366 14.0 0.055 E -154.2 155.0 NA NA NA
TRP H:387 H:366 16.0 0.063 E -153.7 158.4 NA NA NA
6i4u 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 15.0 0.059 E -154.1 159.4 15.0 0.059 0.0 HOH
 2.186
 HE1
 O
TRP B:388 B:366 16.0 0.063 E -154.6 159.6 16.0 0.063 0.0 HOH
 2.054
 HE1
 O
5j5z 1 P09622 99.79 0.0 X-RAY
 2017-11-15 TRP A:388 A:366 17.0 0.067 E -158.4 162.3 17.0 0.067 0.0 HOH
 2.880
 NE1
 O
TRP B:388 B:366 15.0 0.059 E -155.1 161.2 15.0 0.059 0.0 HOH
 2.779
 NE1
 O
6hg8 1 P09622 99.79 0.0 X-RAY
 2019-09-04 TRP A:388 A:366 16.0 0.063 E -160.3 160.6 16.0 0.063 0.0 HOH
 3.000
 NE1
 O
TRP B:388 B:366 19.0 0.075 E -157.1 163.3 19.0 0.075 0.0 SO4
HOH
 8.700
2.939
 CZ2
NE1
 O2
O
6i4r 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 19.0 0.075 E -155.4 159.5 19.0 0.075 0.0 HOH
 2.153
 HE1
 O
TRP B:388 B:366 18.0 0.071 E -155.4 158.4 18.0 0.071 0.0 HOH
 2.092
 HE1
 O
6i4p 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 20.0 0.078 E -154.1 161.6 20.0 0.078 0.0 HOH
 2.714
 HZ2
 O
TRP B:388 B:366 17.0 0.067 E -153.4 159.9 17.0 0.067 0.0 HOH
 1.965
 HE1
 O
6i4s 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 17.0 0.067 E -155.8 160.1 17.0 0.067 0.0 HOH
 2.138
 HE1
 O
TRP B:388 B:366 16.0 0.063 E -153.4 159.0 16.0 0.063 0.0 HOH
 2.081
 HE1
 O
6i4z 1 P09622 99.79 0.0 X-RAY
 2019-11-20 TRP A:388 A:366 18.0 0.071 E -158.1 157.3 18.0 0.071 0.0 HOH
 2.850
 HB3
 O
TRP B:388 B:366 13.0 0.051 E -158.1 158.1 13.0 0.051 0.0 HOH
 3.019
 HB3
 O
TRP C:388 C:366 17.0 0.067 E -157.7 158.5 NA NA NA
TRP D:388 D:366 21.0 0.082 E -157.7 159.9 NA NA NA
TRP E:388 E:366 18.0 0.071 E -155.4 157.2 NA NA NA
TRP F:388 F:366 18.0 0.071 E -155.6 158.3 NA NA NA
TRP G:388 G:366 19.0 0.075 E -155.0 158.1 NA NA NA
TRP H:388 H:366 19.0 0.075 E -156.2 157.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p09622-f1 1 P09622 100.0 0.0 TRP A:401 A:401 19.0 0.075 E -152.2 158.1