Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr7 | 130023239 | . | C | A | CCDS5820.1:NM_001868.2:c.491aCg>aAg_NP_001859.1:p.164T>K | Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5om9 | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2017-08-09 | THR | A:164 | A:54 | 47.0 | 0.336 | S | -106.1 | 9.8 | 47.0 | 0.336 | 0.0 |
HOH |
2.898 |
N |
O |
||
THR | B:164 | B:54 | 43.0 | 0.307 | S | -107.7 | 11.2 | 43.0 | 0.307 | 0.0 |
HOH |
2.918 |
N |
O |
|||||||||
4uf4 | 1 | P15085 | 99.76 | 0.0 |
X-RAY |
2016-01-20 | THR | A:164 | A:164 | 47.0 | 0.336 | S | -105.9 | 8.1 | 47.0 | 0.336 | 0.0 |
HOH |
2.901 |
N |
O |
||
THR | B:164 | B:164 | 43.0 | 0.307 | S | -107.9 | 10.2 | NA | NA | NA | |||||||||||||
1pca | 1 | P09954 | 81.55 | 0.0 |
X-RAY |
1993-10-31 | THR | A:149 | A:54 | 46.0 | 0.329 | S | -113.9 | 16.2 | 46.0 | 0.329 | 0.0 |
HOH |
3.000 |
N |
O |
||
2v77 | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2008-07-01 | THR | A:54 | A:54 | 42.0 | 0.3 | -111.6 | 17.3 | 42.0 | 0.3 | 0.0 |
EPE HOH |
8.112 2.971 |
N N |
O1S O |
|||
THR | B:54 | B:54 | 43.0 | 0.307 | S | -105.8 | 2.7 | NA | NA | NA | |||||||||||||
4uee | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2016-01-20 | THR | A:54 | A:54 | 41.0 | 0.293 | S | -111.3 | 13.2 | 41.0 | 0.293 | 0.0 |
HOH |
3.231 |
N |
O |
||
THR | B:54 | B:54 | 45.0 | 0.321 | S | -100.4 | -2.0 | 45.0 | 0.321 | 0.0 |
HOH |
2.975 |
N |
O |
|||||||||
4uef | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2016-01-20 | THR | A:54 | A:164 | 44.0 | 0.314 | S | -105.7 | 5.0 | 44.0 | 0.314 | 0.0 |
HOH |
2.913 |
N |
O |
||
THR | B:54 | B:164 | 48.0 | 0.343 | S | -112.6 | 9.5 | NA | NA | NA | |||||||||||||
4uez | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2016-01-20 | THR | A:54 | A:164 | 44.0 | 0.314 | S | -103.8 | 5.2 | 44.0 | 0.314 | 0.0 |
HOH |
2.839 |
N |
O |
||
THR | B:54 | B:164 | 45.0 | 0.321 | S | -114.4 | 8.6 | NA | NA | NA | |||||||||||||
6i6z | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2018-12-12 | THR | A:54 | A:164 | 45.0 | 0.321 | S | -106.1 | 5.4 | 45.0 | 0.321 | 0.0 |
HOH |
2.936 |
N |
O |
||
THR | B:54 | B:164 | 45.0 | 0.321 | S | -109.4 | 6.1 | 45.0 | 0.321 | 0.0 |
HOH |
2.963 |
N |
O |
|||||||||
3fju | 1 | P15085 | 100.0 | 0.0 |
X-RAY |
2008-12-30 | THR | A:53 | A:54 | 44.0 | 0.314 | S | -99.2 | 3.7 | 44.0 | 0.314 | 0.0 |
HOH |
2.914 |
N |
O |
||
1pyt | 2 | P00730 | 81.23 | 0.0 |
X-RAY |
1997-01-27 | THR | B:54 | B:54 | 52.0 | 0.371 | -120.1 | -17.5 | 52.0 | 0.371 | 0.0 |
HOH |
2.900 |
O |
O |
|||
3kgq | 1 | P00730 | 81.23 | 0.0 |
X-RAY |
2010-10-27 | THR | A:54 | A:54 | 47.0 | 0.336 | -99.3 | 1.8 | 47.0 | 0.336 | 0.0 |
HOH |
2.871 |
O |
O |
|||
1arm | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
1996-08-17 | THR | A:54 | A:54 | 44.0 | 0.314 | S | -101.5 | 4.6 | 44.0 | 0.314 | 0.0 |
HG HOH |
9.400 2.915 |
CG2 N |
HG O |
||
1ee3 | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2002-06-26 | THR | A:54 | P:54 | 50.0 | 0.357 | S | -105.3 | 3.3 | 50.0 | 0.357 | 0.0 |
HOH |
2.988 |
N |
O |
||
1ell | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2002-06-26 | THR | A:54 | P:54 | 51.0 | 0.364 | S | -102.2 | 2.6 | 51.0 | 0.364 | 0.0 |
HOH |
3.042 |
N |
O |
||
1elm | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2002-06-26 | THR | A:54 | P:54 | 46.0 | 0.329 | S | -106.1 | 6.2 | 46.0 | 0.329 | 0.0 |
HOH |
3.003 |
N |
O |
||
1yme | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
1997-02-12 | THR | A:54 | A:54 | 43.0 | 0.307 | S | -103.8 | 8.9 | 43.0 | 0.307 | 0.0 |
HOH |
2.917 |
N |
O |
||
1zlh | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2005-07-05 | THR | A:54 | A:54 | 45.0 | 0.321 | -102.7 | 11.8 | 45.0 | 0.321 | 0.0 |
HOH |
2.782 |
O |
O |
|||
2abz | 1 | P00730 | 80.91 | 0.0 |
X-RAY |
2006-01-31 | THR | A:54 | A:54 | 46.0 | 0.329 | S | -113.0 | 17.5 | 46.0 | 0.329 | 0.0 | ||||||
THR | B:54 | B:54 | 44.0 | 0.314 | S | -118.7 | 24.3 | 44.0 | 0.314 | 0.0 | |||||||||||||
3hlp | 1 | A6H6Y4 | 80.91 | 0.0 |
X-RAY |
2010-06-02 | THR | A:54 | A:54 | 45.0 | 0.321 | S | -108.1 | 6.7 | 45.0 | 0.321 | 0.0 |
HOH |
2.914 |
N |
O |
||
THR | B:54 | B:54 | 47.0 | 0.336 | -103.4 | 10.3 | NA | NA | NA | ||||||||||||||
3huv | 1 | A6H6Y4 | 80.91 | 0.0 |
X-RAY |
2010-06-02 | THR | A:54 | A:54 | 44.0 | 0.314 | -110.6 | 9.6 | 44.0 | 0.314 | 0.0 |
HOH |
2.930 |
N |
O |
|||
3i1u | 1 | A6H6Y4 | 80.91 | 0.0 |
X-RAY |
2009-11-17 | THR | A:54 | A:54 | 46.0 | 0.329 | S | -101.0 | 0.5 | 46.0 | 0.329 | 0.0 |
HOH |
2.735 |
O |
O |
||
1hdq | 1 | P00730 | 81.43 | 0.0 |
X-RAY |
2001-11-15 | THR | A:54 | A:54 | 46.0 | 0.329 | S | -108.8 | 13.0 | 46.0 | 0.329 | 0.0 |
HOH |
3.174 |
N |
O |
||
2ctb | 1 | P00730 | 81.43 | 0.0 |
X-RAY |
1994-01-31 | THR | A:54 | A:54 | 45.0 | 0.321 | S | -105.9 | 6.0 | 45.0 | 0.321 | 0.0 |
HOH |
2.994 |
N |
O |
||
2ctc | 1 | P00730 | 81.43 | 0.0 |
X-RAY |
1994-01-31 | THR | A:54 | A:54 | 46.0 | 0.329 | -105.7 | 10.4 | 46.0 | 0.329 | 0.0 |
HOH |
2.980 |
N |
O |
|||
1arl | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
1996-08-01 | THR | A:54 | A:54 | 48.0 | 0.343 | S | -108.3 | 12.6 | 48.0 | 0.343 | 0.0 |
HOH |
2.761 |
N |
O |
||
1cpx | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
1998-08-05 | THR | A:54 | A:54 | 46.0 | 0.329 | S | -110.8 | 15.2 | 46.0 | 0.329 | 0.0 |
HOH |
2.767 |
O |
O |
||
1f57 | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2000-09-06 | THR | A:54 | A:54 | 46.0 | 0.329 | S | -101.4 | 2.8 | 46.0 | 0.329 | 0.0 |
HOH |
3.021 |
N |
O |
||
1m4l | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2003-01-10 | THR | A:54 | A:54 | 45.0 | 0.321 | S | -106.1 | 6.9 | 45.0 | 0.321 | 0.0 |
HOH |
2.995 |
N |
O |
||
2rfh | 1 | A6H6Y4 | 81.11 | 0.0 |
X-RAY |
2008-04-22 | THR | A:54 | A:54 | 44.0 | 0.314 | S | -108.8 | 6.5 | 44.0 | 0.314 | 0.0 |
HOH |
2.913 |
N |
O |
||
3fvl | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2010-01-12 | THR | A:54 | A:54 | 41.0 | 0.293 | S | -105.9 | 8.5 | 41.0 | 0.293 | 0.0 |
HOH |
2.912 |
N |
O |
||
THR | B:54 | C:54 | 44.0 | 0.314 | -118.6 | 17.7 | 44.0 | 0.314 | 0.0 |
HOH |
3.096 |
N |
O |
||||||||||
THR | C:54 | E:54 | 44.0 | 0.314 | S | -106.0 | 8.7 | 44.0 | 0.314 | 0.0 |
HOH |
2.793 |
N |
O |
|||||||||
3fx6 | 1 | P00730 | 81.11 | 0.0 |
X-RAY |
2009-08-25 | THR | A:54 | A:54 | 41.0 | 0.293 | S | -107.1 | 9.4 | 41.0 | 0.293 | 0.0 |
HOH |
2.942 |
N |
O |
||
THR | B:54 | C:54 | 43.0 | 0.307 | -119.0 | 16.9 | 43.0 | 0.307 | 0.0 |
HOH |
3.051 |
N |
O |
||||||||||
THR | C:54 | E:54 | 43.0 | 0.307 | S | -107.8 | 10.5 | 43.0 | 0.307 | 0.0 |
HOH |
2.811 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p15085-f1 | 1 | P15085 | 100.0 | 0.0 | THR | A:164 | A:164 | 44.0 | 0.314 | S | -99.4 | 8.1 |