Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130023254 . G A CCDS5820.1:NM_001868.2:c.506cGt>cAt_NP_001859.1:p.169R>H Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 ARG A:169 A:59 65.0 0.289 -60.3 154.8 65.0 0.289 0.0 HOH
 2.758
 O
 O
ARG B:169 B:59 67.0 0.298 -55.6 157.5 67.0 0.298 0.0 HOH
 2.837
 O
 O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 ARG A:169 A:169 65.0 0.289 -57.7 155.6 65.0 0.289 0.0 HOH
 2.767
 O
 O
ARG B:169 B:169 67.0 0.298 -55.0 156.0 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 ARG A:154 A:59 52.0 0.231 -66.2 138.4 52.0 0.231 0.0 HOH
 2.623
 O
 O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 ARG A:59 A:59 58.0 0.258 -62.6 152.5 58.0 0.258 0.0 EPE
HOH
 4.076
2.702
 N
O
 O3S
O
ARG B:59 B:59 66.0 0.293 -59.8 155.7 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ARG A:59 A:59 62.0 0.276 -52.4 155.2 62.0 0.276 0.0 HOH
 2.721
 O
 O
ARG B:59 B:59 65.0 0.289 -57.0 158.6 65.0 0.289 0.0 HOH
 2.682
 O
 O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ARG A:59 A:169 61.0 0.271 -52.1 154.4 61.0 0.271 0.0 HOH
 2.747
 O
 O
ARG B:59 B:169 62.0 0.276 -59.7 155.0 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ARG A:59 A:169 63.0 0.28 -48.1 148.4 63.0 0.28 0.0 HOH
 2.753
 O
 O
ARG B:59 B:169 62.0 0.276 -60.5 155.4 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 ARG A:59 A:169 63.0 0.28 -54.0 155.3 63.0 0.28 0.0 HOH
 2.697
 O
 O
ARG B:59 B:169 64.0 0.284 -57.2 156.7 64.0 0.284 0.0 HOH
 2.817
 O
 O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 ARG A:58 A:59 61.0 0.271 -60.2 154.1 61.0 0.271 0.0 ACT
HOH
 6.666
2.706
 N
O
 CH3
O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 ARG B:59 B:59 63.0 0.28 -74.9 160.9 63.0 0.28 0.0 HOH
 3.491
 CA
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 ARG A:59 A:59 59.0 0.262 -59.5 162.2 59.0 0.262 0.0 GOL
HOH
 8.610
2.708
 O
O
 O3
O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 ARG A:59 A:59 66.0 0.293 -69.8 154.7 66.0 0.293 0.0 HOH
 2.779
 O
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ARG A:59 P:59 65.0 0.289 -65.5 159.7 65.0 0.289 0.0 HOH
 2.778
 O
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ARG A:59 P:59 67.0 0.298 -63.9 158.8 67.0 0.298 0.0 HOH
 2.749
 O
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ARG A:59 P:59 63.0 0.28 -70.0 157.8 63.0 0.28 0.0 HOH
 2.833
 O
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 ARG A:59 A:59 62.0 0.276 -67.6 156.0 62.0 0.276 0.0 HOH
 2.675
 O
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 ARG A:59 A:59 57.0 0.253 -65.9 138.8 57.0 0.253 0.0 HOH
 2.693
 O
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 ARG A:59 A:59 62.0 0.276 -58.7 147.9 62.0 0.276 0.0
ARG B:59 B:59 66.0 0.293 -59.1 161.5 66.0 0.293 0.0
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ARG A:59 A:59 66.0 0.293 -56.1 156.1 66.0 0.293 0.0 HOH
 2.687
 O
 O
ARG B:59 B:59 57.0 0.253 -61.2 156.2 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ARG A:59 A:59 61.0 0.271 -48.5 151.1 61.0 0.271 0.0 HOH
 2.802
 O
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 ARG A:59 A:59 64.0 0.284 -60.0 151.0 64.0 0.284 0.0 GOL
HOH
 8.392
2.694
 O
O
 O3
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 ARG A:59 A:59 65.0 0.289 -71.0 159.1 65.0 0.289 0.0 HOH
 2.847
 NH1
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ARG A:59 A:59 60.0 0.267 -69.9 157.6 60.0 0.267 0.0 HOH
 2.697
 O
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ARG A:59 A:59 61.0 0.271 -68.3 156.8 61.0 0.271 0.0 HOH
 2.701
 O
 O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 ARG A:59 A:59 59.0 0.262 -70.4 157.4 59.0 0.262 0.0 HOH
 2.642
 O
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 ARG A:59 A:59 63.0 0.28 -67.2 159.3 63.0 0.28 0.0 HOH
 2.777
 NH1
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 ARG A:59 A:59 69.0 0.307 -63.2 159.3 69.0 0.307 0.0 HOH
 2.732
 O
 O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 ARG A:59 A:59 65.0 0.289 -53.0 154.1 65.0 0.289 0.0 HOH
 2.808
 O
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 ARG A:59 A:59 54.0 0.24 -59.7 146.7 54.0 0.24 0.0 HOH
 2.669
 O
 O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 ARG A:59 A:59 65.0 0.289 -69.1 157.4 65.0 0.289 0.0 HOH
 2.807
 NE
 O
ARG B:59 C:59 63.0 0.28 -60.8 167.7 63.0 0.28 0.0 HOH
 2.948
 O
 O
ARG C:59 E:59 65.0 0.289 -64.2 151.8 65.0 0.289 0.0 HOH
 2.838
 O
 O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 ARG A:59 A:59 65.0 0.289 -69.7 158.0 65.0 0.289 0.0 HOH
 2.803
 NE
 O
ARG B:59 C:59 61.0 0.271 -61.1 159.7 61.0 0.271 0.0 HOH
 2.911
 O
 O
ARG C:59 E:59 65.0 0.289 -64.4 152.2 65.0 0.289 0.0 HOH
 2.816
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 ARG A:169 A:169 65.0 0.289 -56.0 158.1